Results 131 to 140 of about 55,053 (308)

Herpes simplex virus‐1 infection alters microtubule‐associated protein Tau splicing and promotes Tau pathology in neural models of Alzheimer's disease

Brain Pathology, Volume 35, Issue 5, September 2025.
HSV‐1 infection alters MAPT splicing and promotes Tau pathology in neural models of Alzheimer's disease. HSV‐1 infection in brain organoids and neuronal models increase 4R‐MAPT splicing and Tau hyperphosphorylation. HSV‐1 ICP27 is both necessary and sufficient for inducing these changes highlighting the potential role of HSV‐1 in Alzheimer's disease ...
Emmanuel C. Ijezie, Michael J. Miller, Celine Hardy, Ava R. Jarvis, Timothy F. Czajka, Lianna D'Brant, Natasha Rugenstein, Adam Waickman, Eain Murphy, David C. Butler   +9 more
wiley   +1 more source

Clinical and Laboratory Features of Infectious Mononucleosis in Children Depending on the Etiology of the Disease

Детские инфекции (Москва), 2016
Study of clinical and laboratory features of infectious mononucleosis (IM) in children depending on the etiological variant of the disease. The study involved 94 children aged 4 months to 15 years old with a diagnosis of «infectious mononucleosis».
D. V. Dutlova, O. I. Urazova, A. P. Pomogaeva   +2 more
doaj   +1 more source

Simultaneous Detection of Beta and Gamma Human Herpesviruses by Multiplex qPCR Reveals Simple Infection and Coinfection Episodes Increasing Risk for Graft Rejection in Solid Organ Transplantation

Viruses, 2018
Herpesviruses are common components of the human microbiome that become clinically relevant when a competent immunosurveillance is compromised, such as in transplantation.
Yessica Sánchez-Ponce, G. Varela-Fascinetto, J. C. Romo-Vázquez, B. López-Martínez, J. Sánchez-Huerta, I. Parra-Ortega, E. Fuentes-Pananá, A. Morales-Sánchez   +7 more
semanticscholar   +1 more source

Diagnostic electron microscopy in human infectious diseases – Methods and applications

Journal of Microscopy, Volume 299, Issue 3, Page 186-205, September 2025.
Abstract Diagnostic electron microscopy (EM) is indispensable in all cases of infectious diseases which deserve or profit from the detection of the entire pathogen (i.e. the infectious unit). The focus of its application has shifted during the last decades from routine diagnostics to diagnostics of special cases, emergencies and the investigation of ...
Michael Laue
wiley   +1 more source

Herpesviruses in Head and Neck Cancers

Viruses, 2019
Head and neck cancers arise in the mucosa lining the oral cavity, oropharynx, hypopharynx, larynx, sinonasal tract, and nasopharynx. The etiology of head and neck cancers is complex and involves many factors, including the presence of oncogenic viruses ...
Mikołaj Wołącewicz, R. Becht, E. Grywalska, P. Niedźwiedzka-Rystwej   +3 more
semanticscholar   +1 more source

The Antiviral Activity of Polyphenols

Molecular Nutrition &Food Research, Volume 69, Issue 15, August 2025.
Polyphenols demonstrate remarkable antiviral properties by effectively disrupting multiple biochemical processes essential for viral replication. ABSTRACT Polyphenols are secondary metabolites produced by a large variety of plants. These compounds that comprise the class of phenolic acids, stilbenes, lignans, coumarins, flavonoids, and tannins have a ...
Markus Burkard, Alban Piotrowsky, Christian Leischner, Katja Detert, Sascha Venturelli, Luigi Marongiu   +5 more
wiley   +1 more source

A murine herpesvirus closely related to ubiquitous human herpesviruses causes T-cell depletion [PDF]

, 2017
The human roseoloviruses human herpesvirus 6A (HHV-6A), HHV-6B, and HHV-7 comprise the Roseolovirus genus of the human Betaherpesvirinae subfamily. Infections with these viruses have been implicated in many
Beatrice Plougastel-Douglas, Daved H. Fremont, David Wang, Elvin J. Lauron, Eugene Park, Guoyan Zhao, Ian B. Harvey, Jennifer Poursine-Laurent, Swapneel J. Patel, Vinay R. Penna, Wandy L. Beatty, Wayne M. Yokoyama   +11 more
core   +2 more sources

Post‐COVID‐19 condition: clinical phenotypes, pathophysiological mechanisms, pathology, and management strategies

The Journal of Pathology, Volume 266, Issue 4-5, Page 369-389, August 2025.
Abstract Post‐COVID‐19 condition (PCC), also known as long COVID, is a complex multiple organ system condition that can develop and persist for months after acute COVID‐19. PCC encompasses a wide range of symptoms, resulting in heterogeneous clinical manifestations. These manifestations likely arise from diverse underlying pathophysiological mechanisms,
Larissa E Vlaming‐van Eijk, Guolu Tang, Arno R Bourgonje, Wilfred F A den Dunnen, Jan‐Luuk Hillebrands, Harry van Goor   +5 more
wiley   +1 more source

Conserved Herpesvirus Protein Kinases Target SAMHD1 to Facilitate Virus Replication

Cell Reports, 2019
Summary: To ensure a successful infection, herpesviruses have developed elegant strategies to counterbalance the host anti-viral responses. Sterile alpha motif and HD domain 1 (SAMHD1) was recently identified as an intrinsic restriction factor for a ...
Kun Zhang, Dong-Wen Lv, Renfeng Li
doaj  

Polymicrobial periodontal disease triggers a wide radius of effect and unique virome. [PDF]

, 2020
Periodontal disease is a microbially-mediated inflammatory disease of tooth-supporting tissues that leads to bone and tissue loss around teeth. Although bacterially-mediated mechanisms of alveolar bone destruction have been widely studied, the effects of
Gao, Li, Ho, Sunita P, Kamarajan, Pachiyappan, Kang, Misun, Kapila, Yvonne L, Kuraji, Ryutaro, Le, Charles, Martinez, April, Rangé, Hélène, Reza Sailani, M, Ye, Changchang, Zhan, Ling, Zhang, Martin Jinye   +12 more
core