Results 71 to 80 of about 34,500 (215)

Advances in the mechanism of inflammasomes activation in herpes virus infection

Frontiers in Immunology
Herpesviruses, prevalent DNA viruses with a double-stranded structure, establish enduring infections and play a part in various diseases. Despite their deployment of multiple tactics to evade the immune system, both localized and systemic inflammatory ...
Hourui Chen, Zhijie Jian, Tong Xu, Lei Xu, Lishuang Deng, Lina Shao, Leyi Zhang, Li He, Youyou Li, Ling Zhu   +9 more
doaj   +1 more source

The Fusion Loops of the Initial Prefusion Conformation of Herpes Simplex Virus 1 Fusion Protein Point Toward the Membrane

mBio, 2017
All enveloped viruses, including herpesviruses, must fuse their envelope with the host membrane to deliver their genomes into target cells, making this essential step subject to interference by antibodies and drugs.
Juan Fontana, Doina Atanasiu, Wan Ting Saw, John R. Gallagher, Reagan G. Cox, J. Charles Whitbeck, Lauren M. Brown, Roselyn J. Eisenberg, Gary H. Cohen   +8 more
doaj   +1 more source

Natural Infection by Toscana Virus and Other Phleboviruses in Wild Sand Flies From Spain: Prevalence, Genetic Characterization and Tripartite Interactions With Leishmania infantum and Wolbachia

Zoonoses and Public Health, EarlyView.
ABSTRACT Introduction Toscana virus (TOSV) and Leishmania species are sand fly‐borne pathogens that pose a significant public health threat and an increasing risk of exposure in Europe. The objective of this study was to identify the phleboviruses circulating in an area endemic for sand fly‐borne pathogens and to estimate infection prevalence in wild ...
Andrés Torres‐Llamas, Antonio Sampedro, Victoriano Díaz‐Sáez, Manuel Morales‐Yuste, Javier Rodríguez‐Granger, Irene Pedrosa‐Corral, José María Navarro‐Marí, Francisco Morillas‐Márquez, Joaquina Martín‐Sánchez   +8 more
wiley   +1 more source

Post‐Transplant Bendamustine as a Platform for Immune Modulation After Allogeneic Hematopoietic Cell Transplantation

European Journal of Haematology, Volume 117, Issue 4, Page 739-749, October 2026.
ABSTRACT Post‐transplant cyclophosphamide (PT‐CY) remains the standard of care for graft‐versus‐host disease (GvHD) prophylaxis in haploidentical hematopoietic cell transplantation (HCT), yet relapse, delayed immune reconstitution, infections, and organ toxicity represent persistent and clinically meaningful limitations.
Megan J. Cracchiolo, Richard J. Simpson, Emmanuel Katsanis   +2 more
wiley   +1 more source

Equine Multinodular Pulmonary Fibrosis Associated with Equine Herpesvirus 5 in a Horse in Brazil

Brazilian Journal of Veterinary Pathology, 2014
This report describes the first diagnosed case of equine multinodular pulmonary fibrosis associated with equine herpesvirus 5 (EHV-5) in a horse in Brazil.
Welden Panziera, Paula R. Giaretta, Glauco J. N. Galiza, Ailam Lim, Steven R. Bolin, Carlos H. Borges, Rafael A. Fighera, Claudio S. L. Barros   +7 more
doaj   +1 more source

The IL‐10/IL‐6 Ratio and the Risk Score: Two Cytokines‐Based Predictors for Malignancy‐Associated Hemophagocytic Lymphohistiocytosis in Adults (M‐HLHa)

American Journal of Hematology, Volume 101, Issue 9, Page 2214-2224, September 2026.
ABSTRACT The predictive value of cytokines (CK) for malignancy‐associated adult hemophagocytic lymphohistiocytosis (M‐HLHa) remains uncertain. We evaluated a cytokine‐based Risk Score (RS) and the IL‐10/IL‐6 Ratio to predict M‐HLHa. Adult patients (n = 112) from the French HLH cohort (NCT02113917) with complete data for nine key HLH related CK measured
Coralie Bloch, Stephanie Chhun, Nanthara Sritharan, Marine Gil, Raphael Lhote, Marouane Boubaya, Olivier Lambotte, David Launay, Claire Larroche, Estibaliz Lazaro, Francois Liffermann, Marc Michel, Jean‐Marie Michot, Pierre Morel, Louis Terriou, Geoffrey Urbansk, Jean‐Francois Viallard, Morgane Cheminant, Felipe Suarez, Yves Lepelletier, Geneviève de Saint Basile, Olivier Hermine, the French HLH Study Group, Coralie Bloch, Jean Philippe Jais, Francois Liffermann, Pierre Morel, Morgane Cheminant, Felipe Suarez, Olivier Hermine, Fabrice Bonnet, Pascal Godemer, Damaj Gandhi, Olivier Fain, Olivier Lambotte, David Launay, Louis Terriou, Claire Larroche, Estibaliz Lazaro, Jean‐Francois Viallard, Francois Liffermann, Olivier Lortholary, Marc Michel, Jean‐Marie Michot, Pierre Morel, Frederic Pene, Antoinette Perlat, Geoffrey Urbanski   +47 more
wiley   +1 more source

Longitudinal study on oral shedding of human betaherpesviruses 6 and 7 in renal transplant recipients reveals active replication

Journal of Oral Microbiology, 2020
Backgroung Roseolovirus latency and persistence in salivary glands that are frequently reactivated after renal transplantation to cause infection have been reported.
Jéssica Vasques Raposo, Dmitry José De Santana Sarmento, Rafaela Barbosa Da Silva Pinto, Amanda Oliveira Lopes, Marina Gallottini, Tânia Regina Tozetto-Mendoza, Paulo Henrique Braz-Silva, Vanessa Salete de Paula   +7 more
doaj   +1 more source

The Significance of cGAS‐STING Signaling in Response to Oncogenic Viruses

Cell Biochemistry and Function, Volume 44, Issue 9, September 2026.
ABSTRACT The cyclic GMP‐AMP synthase (cGAS)‐stimulator of interferon genes (STING) signaling pathway, as a key DNA sensor, plays a significant role in the regulation of innate immune responses. This pathway can be activated by sensing abnormal DNA, and is of great significance for resisting the invasion of pathogenic microorganisms and maintaining ...
Limei Guo, Li Li, Fang Wang, Wen Liu, Yan Zhang   +4 more
wiley   +1 more source

DETECTION OF HERPESVIRUS INFECTIONS IN CHILDREN OF THE FIRST SIX MONTHS OF LIFE

Журнал микробиологии, эпидемиологии и иммунобиологии, 2018
Aim. To evaluate a possible role of herpes viruses in the pathogenesis of various infectious diseases of children in the first six months of life, including acute gastroenteritis and identify the markers of herpesvirus infections which occur most ...
E. M. Burmistrov, T. N. Rybalkina, N. V. Karazhas, R. E. Boshyan, P. A. Veselovsky, M. Yu. Lysenkova, E. R. Meskina, T. V. Stashko   +7 more
doaj   +1 more source

HHV‐6–Positive Meningitis in an Immunocompetent Adult: Diagnostic Challenges in Distinguishing Active Infection From Chromosomal Integration: A Case Report

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Consider human herpesvirus 6 (HHV‐6) in immunocompetent adults with viral meningitis when standard tests are negative. Qualitative CSF PCR requires cautious interpretation because it cannot exclude chromosomally integrated HHV‐6. Serial CSF improvement and rapid clinical recovery may support probable self‐limited infection and help avoid ...
Hatem M. Taha, Anwar Zahran, Orabi Hajjeh, Bara AbuBaha, Mohammed AbuBaha, Omar Marouf   +5 more
wiley   +1 more source