Results 131 to 140 of about 6,792 (174)
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Glycosylation of hesperetin by plant cell cultures
Phytochemistry, 2008The biotransformation of hesperetin by cultured cells of Ipomoea batatas and Eucalyptus perriniana was investigated. Three glycosides, hesperetin 3'-O-beta-D-glucopyranoside (33 microg/g fr. wt of cells), hesperetin 3',7-O-beta-D-diglucopyranoside (217 microg/g fr.
Hiroki Hamada +2 more
exaly +3 more sources
UPLC–MS/MS quantification of total hesperetin and hesperetin enantiomers in biological matrices
Journal of Pharmaceutical and Biomedical Analysis, 2012Hesperidin (hesperetin-7-O-rutinoside), a flavonoid affecting vascular function, is abundant in citrus fruits and derived products such as juices. After oral administration, hesperidin is hydrolyzed by the colonic microbiota producing hesperetin-7-O-glucoside, the glucoside group is further cleaved and the resulting hesperetin is absorbed and ...
Lucas Actis-Goretta +2 more
exaly +3 more sources
Neuroprotective effects of chronic hesperetin administration in mice
Archives of Pharmacal Research, 2008Flavonoids are considered therapeutic agents in neurodegenerative disease because of their neuroprotective activity. This study investigated the neuroprotective effects of hesperetin in the brains of mice administered hesperetin at 10 or 50 mg/kg body weight (BW) for five weeks.
Eun Jeong Choi, Woong Shick Ahn
exaly +3 more sources
Scavenging of Toxic Acrolein by Resveratrol and Hesperetin and Identification of Adducts
Journal of Agricultural and Food Chemistry, 2015The objective of this study was to investigate the ability of resveratrol and hesperetin to scavenge acrolein at pH 7.4 and 37 °C. About 6.4 or 5.2% of acrolein remained after reaction with resveratrol or hesperetin for 12 h at equimolar concentrations. An acrolein-resveratrol adduct and two acrolein-hesperetin adducts were isolated.
Liwei Gu, Yajing Qi, Paul Sarnoski
exaly +3 more sources
Nanosuspensions of hesperetin: preparation and characterization
Die Pharmazie, 2014Nanosuspensions are a smart formulation principle for dermal applications, as they increase the penetration of poorly soluble substances into the skin. Because microbial stability is a pre-requisite for dermal formulations, water containing formulations need to be preserved.
L, Al Shaal +3 more
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Hypocholesterolemic Activity of Hesperetin Derivatives.
ChemInform, 2003AbstractFor Abstract see ChemInform Abstract in Full Text.
Tae-Sook, Jeong +8 more
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Preserving hesperetin nanosuspensions for dermal application.
Die Pharmazie, 2010Nanosuspensions as aqueous formulations need to be preserved. However, preservatives could vitiate the physical stability of suspensions and to a greater extent nanosuspensions. The impact of six varied preservatives on the physical stability of previously prepared nanosuspensions was studied.
Al Shaal, L. +2 more
openaire +3 more sources
Journal of Radioanalytical and Nuclear Chemistry, 2015
The purpose of this study is to synthesize 123I-labeled hesperetin and to investigate its in vivo behavior. The optimized labeling condition provided two isomers of 123I-labeled hesperetin with high radiochemical yields and radiochemical purities. Both 123I-labeled products were orally administered to normal ICR mice, and the initial result showed that
Jongho Jeon +7 more
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The purpose of this study is to synthesize 123I-labeled hesperetin and to investigate its in vivo behavior. The optimized labeling condition provided two isomers of 123I-labeled hesperetin with high radiochemical yields and radiochemical purities. Both 123I-labeled products were orally administered to normal ICR mice, and the initial result showed that
Jongho Jeon +7 more
openaire +1 more source
Antilipolytic Action of Hesperetin in Rat Adipocytes
Planta Medica, 1993Hesperetin was able to inhibit both epinephrine- and theophylline-induced lipolysis in rat adipocytes. At concentrations of 125 microM and 250 microM, it could augment the inhibitory effect of low insulin concentration (17 microU/2ml) on epinephrine-induced lipolysis.
Kuppusamy, U.R., Das, N.P.
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