Results 71 to 80 of about 6,792 (174)

Computational and Experimental Approaches Exploring the Role of Hesperetin in Improving Autophagy in Rat Diabetic Retinopathy

Biomedicines
Diabetic retinopathy (DR) is a debilitating diabetic disorder of the retinal microvasculature and the main cause of avoidable blindness in old people. Hesperetin is a plant flavanone largely abundant in citrus species with neuroprotective properties in ...
Reem Alshaman, Eman Kolieb, Rehab M. El-Sayed, Sahar Galal Gouda, Abdullah Alattar, Sawsan A. Zaitone, Asmaa K. K. Abdelmaogood, Lamiaa M. Elabbasy, Amira H. Eltrawy, Fai Yahya Sayd, Hatem I. Mokhtar, Esam Ghanem Abu El Wafa, Esam Sayed Ahmed, Dong Liang, Dina A. Ali   +14 more
doaj   +1 more source

Antihyperglycemic and Antihyperlipidemic Effect of Chronic Administration of Hesperetin in Diabetic Rats

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2010
BACKGROUND AND OBJECTIVE: Diabetes mellitus is one of the most important risk factors for incidence of nephropathy, retinopathy, neuropathy, and cardiovascular disorders.
M Roghani, P Baluchnejadmojarad, F Roghani-Dehkordi   +2 more
doaj  

Neuroprotective effect of hesperetin and nano-hesperetin on recognition memory impairment and the elevated oxygen stress in rat model of Alzheimer’s disease

Biomedicine & Pharmacotherapy, 2018
Alzheimer disease (AD) is a progressive dementia affecting a large proportion of the aging population. There is evidence that brain tissue in patients with AD is exposed to oxidative stress during the course of the disease. Hesperetin (Hst) is a natural flavonoid, which has been reported to exert various biological activities such as antioxidant and ...
Elham, Kheradmand, Akbar, Hajizadeh Moghaddam, Mahboobeh, Zare   +2 more
openaire   +2 more sources

Hesperetin alleviates aflatoxin B1 induced liver toxicity in mice: Modulating lipid peroxidation and ferritin autophagy

Ecotoxicology and Environmental Safety
One of the ways Aflatoxin B1 damages the liver is through ferroptosis. Ferroptosis is characterized by the build-up of lipid peroxides and reactive oxygen species (ROS) due to an excess of iron.
Chao Song, Zixu Wang, Jing Cao, Yulan Dong, Yaoxing Chen   +4 more
doaj   +1 more source

The Flavonoid Hesperetin Alleviates Behavioral Abnormality in 6-Hydroxydopamine Rat Model of Hemi-Parkinsonism

Basic and Clinical Neuroscience, 2010
Parkinson’s disease (PD) is a neuropathological and debilitating disorder involving the degeneration of mesencephalic dopaminergic neurons. Neuroprotective effect of hesperetin has already been reported, therefore, this study examined whether the ...
Tourandokht Baluchnejadmojarad, Mehrdad Roghani   +1 more
doaj   +2 more sources

Recent understanding of the mechanisms of the biological activities of hesperidin and hesperetin and their therapeutic effects on diseases

Heliyon
Flavonoids are natural phytochemicals that have therapeutic effects and act in the prevention of several pathologies. These phytochemicals can be found in lemon, sweet orange, bitter orange, clementine.
Zhongkai Ji, Wei Deng, Dong Chen, Zhidong Liu, Yucheng Shen, Jiuming Dai, Hai Zhou, Miao Zhang, Hucheng Xu, Bin Dai   +9 more
doaj   +1 more source

The Flavonoid Hesperetin Alleviates Behavioral Abnormality in 6-Hydroxydopamine Rat Model of Hemi-Parkinsonism

Basic and Clinical Neuroscience, 2011
Parkinson's disease (PD) is a neuropathological and debilitating disorder involving the degeneration of mesencephalic dopaminergic neurons. Neuroprotective effect of hesperetin has already been reported, therefore, this study examined whether the ...
Tourandokht Baluchnejadmojarad, Mehrdad Roghani   +1 more
doaj  

Exploring the Antimicrobial Potential of Hesperetin: A Study on Clinically Relevant Bacterial and Fungal Pathogens

Journal of Pure and Applied Microbiology
Hesperetin, a natural flavonoid, has been investigated for its potential therapeutic properties. In this study, we delve into its antimicrobial and antiviral activities against clinically relevant bacterial and fungal strains.
Assim Verma, Jyoti Bakshi, Garvit Kumar, Himanshu Kamboj, Rekha Verma, Pooja Vijayaraghavan, Aman Singh, Naveen Kumar, Sanjay Barua, Santosh Kumari   +9 more
doaj   +1 more source

Chiral Separation of Hesperetin and Hesperetin-O-glycoside in Capillary Electrophoresis Using Microbial β-1,2-Glucans

Bulletin of the Korean Chemical Society, 2009
there have been no further reports. Herein, in the present study, enantiosepara-tions of some flavonoids with these linear and anionic cyclic glucans were investigated. Flavonoids which are a class of plant secondary metabolites are distributed in fruits, vegetables, tea or even red wine.
openaire   +2 more sources

Cellular electrophysiological effects of the citrus flavonoid hesperetin in dog and rabbit cardiac ventricular preparations

Scientific Reports
Recent experimental data shows that hesperetin, a citrus flavonoid, affects potassium channels and can prolong the QTc interval in humans. Therefore, in the present study we investigated the effects of hesperetin on various transmembrane ionic currents ...
Aiman Saleh A. Mohammed, Gábor Mohácsi, Muhammad Naveed, János Prorok, Norbert Jost, László Virág, István Baczkó, Leila Topal, András Varró   +8 more
doaj   +1 more source