Results 51 to 60 of about 6,792 (174)

Unraveling the Bioactive Compounds and Multi‐Target Mechanisms of the Fructus Aurantii Immaturus‐Bambusae Caulis in Taeniam Herb Pair Against Chronic Gastritis: Integrating Identification of Absorbed Constituents, Targeted Network Pharmacology, and Computational Validation

Food Science &Nutrition, Volume 14, Issue 7, July 2026.
This work systematically explored the anti‐chronic gastritis mechanism of the FAI‐BCT herb pair. UPLC‐Q‐TOF‐MS/MS was applied to identify absorbed prototypes and metabolites of FAI‐BCT in rat plasma. Combining database mining, network pharmacology, molecular docking, and molecular dynamics simulation, we screened the key bioactive components and core ...
Yinghua Ma, Weiwei Xie, Jing Song, Yabin Qin, Yile Zhao   +4 more
wiley   +1 more source

Microbial production of the plant flavanone hesperetin from caffeic acid

BMC Research Notes, 2023
Objective Hesperetin is an important O-methylated flavonoid produced by citrus fruits and of potential pharmaceutical relevance. The microbial biosynthesis of hesperetin could be a viable alternative to plant extraction, as plant extracts often yield ...
Erik K. R. Hanko, João Correia, Caio S. Souza, Alison Green, Jakub Chromy, Ruth Stoney, Cunyu Yan, Eriko Takano, Diana Lousa, Cláudio M. Soares, Rainer Breitling   +10 more
doaj   +1 more source

From Green Extraction to Gut Bioaccessibility: Synergistic Potential of Ginkgo biloba, Astragalus membranaceus, and Salvia miltiorrhiza Phytochemicals for Functional Food Applications

Food Science &Nutrition, Volume 14, Issue 7, July 2026.
This study optimized green extraction of a synergistic tri‐herbal blend of Ginkgo biloba, Astragalus membranaceus, and Salvia miltiorrhiza. The 1:1:2 blend showed the highest TPC synergy, with probe ultrasound giving maximal phenolic recovery. The extract, rich in rosmarinic acid, chlorogenic acid, and catechin, exhibited antioxidant, antimicrobial ...
Mohamed Ibrahim Younis, Yahia Ibrahim Sallam, Khaled Fahmy Mahmoud, Rawaa H. Tlay, M. Ali Aboudzadeh, Tarek Gamal Abedelmaksoud   +5 more
wiley   +1 more source

Protective effects of hesperetin on the quality of sperm, apoptosis, lipid peroxidation, and oxidative stress during the process of cryopreservation: An experimental study

International Journal of Reproductive BioMedicine, 2021
Background: Hesperetin is a bioflavonoid compound, largely used in Chinese traditional medicine and found plenty in citrus fruits. Hesperetin has beneficial effects against different diseases. The sperm cryopreservation process is a common method that is
Jamal Valipour, Sina Mojaverrostami, Beheshteh Abouhamzeh, Masoumeh Abdollahi   +3 more
doaj   +1 more source

Optimizing Extraction and HPLC‐ESI‐QTOF‐MS/MS Analysis of Bound Phenolics From Okra (Abelmoschus esculentus) and Their Biological Activity

Food Science &Nutrition, Volume 14, Issue 7, July 2026.
Extraction and characterization of okra bound phenolics. The extraction of bound phenolics from okra pulp (OPBP) and seeds (OSBP) was optimized, achieving maximum yields of 7.77 and 83.03 mg GAE/g DW, respectively. Using HPLC‐ESI‐QTOF‐MS/MS, multiple phenolic compounds were identified, with nine being reported in okra for the first time.
Bingjie Zhang, Rongjuan Liu, Hong Zhang, Ting Xv, Yue Lv, Yuan Xv, Haiqiang Chen, Hu Zhu, Xiaolin Shi, Mingyan Yan, Yinping Li   +10 more
wiley   +1 more source

Ameliorative Effects of Newly Developed Citrus Hybrid “Mubong” Peel Extract on Experimental Colitis and Gut Microbiota Dysbiosis

Food Science &Nutrition, Volume 14, Issue 7, July 2026.
DSS exposure induces severe colitis, causing gut dysbiosis and mucosal inflammation driven by NF‐κB activation and spikes in pathogenic bacteria, TNF‐α, and IL‐6. However, “Mubong” Peel Extract effectively disrupts this inflammatory cascade. By suppressing NF‐κB‐dependent transcriptional activity, the extract mitigates clinical symptoms like colon ...
Awraris Derbie Assefa, Sang Suk Kim, Seung‐Gab Han, YoSup Park, Jee‐Soo Park   +4 more
wiley   +1 more source

Ceramide generation as a novel biological mechanism for chemo-preventive and cytotoxic effects of hesperidin on HT-144 melanoma cells

Beni-Suef University Journal of Basic and Applied Sciences, 2018
Introduction: Hesperidin and its aglycone, hesperetin are abundant natural flavonoid in Citrus and known for their anti-neoplastic and pro-apoptotic properties.
Mahdi Mashhadi Akbar Boojar, Masoud Mashhadi Akbar Boojar, Sepide Golmohammad, Mojtaba Nikkhah Yazdi   +3 more
doaj   +1 more source

Comparison of the Metabolites in Fingered Citron Fruit (Citrus medica L. var. sarcodactylis Swingle) and Chayote (Sechium edule) Based on UPLC‐Q‐Orbitrap MS/MS

Food Science &Nutrition, Volume 14, Issue 7, July 2026.
Untargeted UPLC‐Q‐Orbitrap MS/MS metabolomics was used to profile fingered citron (Citrus medica) from four Chinese production regions (CF1–CF4) and chayote (Sechium edule, CFM). Of 380 putatively annotated metabolites, 65 differential metabolites distinguished the five groups, clearly separating chayote from fingered citron and highlighting regional ...
Bin Li, Ruiyi Fan
wiley   +1 more source

Phytochemical Profiling and Evaluation of Antioxidant and Enzyme Inhibitory Activities of Selected Endemic Salvia Species (Lamiaceae) From Türkiye

Food Science &Nutrition, Volume 14, Issue 7, July 2026.
The aerial parts extract of Salvia vermifolia exhibited notable inhibitory activity against α‐glucosidase and α‐amylase enzymes and demonstrated strong radical scavenging activities in the DPPH and ABTS assays. ABSTRACT Salvia (Lamiaceae) species have been used in food, cosmetics, and medicine for centuries. Besides their use as food, these species are
Semih Bulut, Sümeyye Usta, Ahmet Kahraman, Mustafa Abdullah Yilmaz, Oguz Cakir, Muhammed Tilahun Muhammed   +5 more
wiley   +1 more source

The effects of hesperetin on apoptosis induction and inhibition of cell proliferation in the prostate cancer PC3 cells [PDF]

Journal of HerbMed Pharmacology, 2015
ntroduction: Prostate cancer is the second leading cause of cancer-related deaths and the mostcommon cancer diagnosed in men in the United States and Europe.
Shirzad Moein, Beshkar Pezhman, Heidarian Esfandiar   +2 more
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