Results 241 to 250 of about 133,661 (356)

Histopathological Alterations and Dysregulation of Type I Interferon Signaling in the Human Cerebral Cortex During Severe Dengue

open access: yesJournal of Medical Virology, Volume 97, Issue 10, October 2025.
ABSTRACT Dengue virus (DENV) is a major arthropod‐borne pathogen, endemic in over 100 countries and posing global health challenges. While innate immune responses and viral evasion mechanisms have been extensively studied in animal models and mononuclear cells, severe dengue can affect multiple tissues, including the central nervous system (CNS ...
Leandro Mantovani de Castro   +10 more
wiley   +1 more source

Fencing the genome: ubiquitin signaling restricts heterochromatin spread. [PDF]

open access: yesSignal Transduct Target Ther
Bakker C, Paulson J, Taneja N.
europepmc   +1 more source

Constitutive heterochromatin distribution in pig (Sus scrofa) chromosomes [PDF]

open access: bronze, 1998
G.P. Di Meo   +5 more
openalex   +1 more source

Role of H3K9me3 heterochromatin in cell identity establishment and maintenance.

open access: yesCurrent Opinion in Genetics and Development, 2019
Dario Nicetto, K. Zaret
semanticscholar   +1 more source

Revealing the biophysics of lamina-associated domain formation by integrating theoretical modeling and high-resolution imaging. [PDF]

open access: yesNat Commun
Dhankhar M   +9 more
europepmc   +1 more source

Gene Therapy Targeting Pkp2 Deficiency Attenuates Cardiac Fibrosis: Insights From Single‐Cell Transcriptomics in Pkp2‐Knockout Rats

open access: yesMedComm, Volume 6, Issue 10, October 2025.
PKP2 acts as a master switch for the progression of fibrosis in heart failure. ABSTRACT Heart failure (HF), characterized by maladaptive cardiac fibrosis and progressive functional deterioration, remains a therapeutic challenge. In this study, we established a cardiac organoid HF model derived from human‐induced pluripotent stem cells (hiPSCs) and ...
Xinyue Ding   +11 more
wiley   +1 more source

Requirements for establishment and epigenetic stability of mammalian heterochromatin. [PDF]

open access: yesMol Cell
Tatarakis A   +5 more
europepmc   +1 more source

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