Results 131 to 140 of about 603,291 (199)

The role of inner nuclear membrane protein emerin in myogenesis

The FASEB Journal, Volume 39, Issue 7, 15 April 2025.
Emerin function is critical for proper genome reorganization and temporal gene expression necessary for terminal myogenic differentiation. Emerin interacts with both HDAC3 and histone methyltransferases (HMTs) to organize chromatin at the inner nuclear membrane.
Nicholas Marano, James M. Holaska
wiley   +1 more source

Functional Characterization of LIKE HETEROCHROMATIN PROTEIN 1 in the moss Physcomitrella patens : its conserved protein interactions in land plants [PDF]

, 2018
Vimala Parihar, Deepshikha Arya, Akanksha Walia, Vidhi Tyagi, Meenakshi Dangwal, Vibha Verma, Ridhi Khurana, Neelima Boora, Sanjay Kapoor, Meenu Kapoor   +9 more
openalex   +1 more source

Expression of heterochromatin protein 1 affects citric acid production in Aspergillus luchuensis mut. kawachii

, 2023
Atsushi Nishitani, Kentaro Hiramatsu, Chihiro Kadooka, Kazuki Mori, Kayu Okutsu, Yumiko Yoshizaki, Kazunori Takamine, Kosuke Tashiro, Masatoshi Goto, Hisanori Tamaki, Taiki Futagami   +10 more
openalex   +1 more source

Transcriptional Profiling of Tofacitinib Treatment in Juvenile Idiopathic Arthritis: Implications for Treatment Response Prediction

Arthritis Care &Research, Volume 77, Issue 4, Page 513-521, April 2025.
Objective To assess changes in gene expression following tofacitinib treatment and investigate transcription patterns as potential predictors of treatment response in patients with active juvenile idiopathic arthritis (JIA). Methods Whole‐blood samples were collected from patients with JIA at baseline and after 18 weeks of open‐label tofacitinib ...
Esraa Eloseily, Alex Pickering, Sanjeev Dhakal, Nicolino Ruperto, Hermine I. Brunner, Alexei A. Grom, Sherry Thornton, for the Pediatric Rheumatology Collaborative Study Group and the Paediatric Rheumatology International Trials Organisation   +7 more
wiley   +1 more source

Comparison of three heterochromatin protein 1 homologs in Drosophila [PDF]

, 2019
Dong Hoon Lee, Hyun Wook Ryu, Go Woon Kim, So Hee Kwon   +3 more
openalex   +1 more source

3D Mechanical Confinement Directs Muscle Stem Cell Fate and Function

Advanced Biology, Volume 9, Issue 4, April 2025.
This study reveals that the physical environment surrounding muscle stem cells (MuSCs) plays a crucial role in their function. Using a 3D hydrogel system, it shows that increased confinement preserves MuSC stemness by limiting activation, proliferation, and differentiation.
GaYoung Park, Josh A. Grey, Foteini Mourkioti, Woojin M. Han   +3 more
wiley   +1 more source

Recruitment of Tat to Heterochromatin Protein HP1 via Interaction with CTIP2 Inhibits Human Immunodeficiency Virus Type 1 Replication in Microglial Cells

, 2003
Olivier Rohr, Dominique Lecestre, Sylvette Chasserot‐Golaz, Céline Marban, Dorina Avram, Dominique Aunis, Mark Leid, Evelyne Schaeffer   +7 more
openalex   +1 more source

Hybrid EMT Phenotype and Cell Membrane Tension Promote Colorectal Cancer Resistance to Ferroptosis

Advanced Science, Volume 12, Issue 15, April 17, 2025.
Colorectal cancer cells (CRCs) cultured in 3D soft fibrin exhibit hybrid epithelial–mesenchymal transition (EMT) mediated ferroptosis resistance via WNT/β‐catenin signaling. Unlike 2D cells, 3D CRCs exhibit reduced E‐cadherin, knockout of which further enhances the defense against ferroptosis via adhesion‐mediated tension.
Xiaowei Wei, Yutong Ge, Yaolin Zheng, Sunyan Zhao, Yuhan Zhou, Yuhan Chang, Nuofan Wang, Xiumei Wang, Juan Zhang, Xuanchang Zhang, Liqiao Hu, Youhua Tan, Qiong Jia   +12 more
wiley   +1 more source

Transcriptomic and Metabolomic Analyses in Monozygotic and Dizygotic Twins

American Journal of Medical Genetics Part A, Volume 197, Issue 4, April 2025.
ABSTRACT Monozygotic (MZ) and dizygotic (DZ) twins are studied to understand genetic and environmental influences on complex traits, however the mechanisms behind twinning are not completely understood. (Epi)genomic studies identified SNPs associated with DZ twinning and DNA methylation sites with MZ twinning.
Nikki Hubers, Gabin Drouard, Rick Jansen, René Pool, Jouke Jan Hottenga, Miina Ollikainen, Xiaoling Wang, Gonneke Willemsen, Jaakko Kaprio, Dorret I. Boomsma, Jenny van Dongen   +10 more
wiley   +1 more source

Functions and Therapeutic Potentials of Long Noncoding RNA in Skeletal Muscle Atrophy and Dystrophy

Journal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 2, April 2025.
ABSTRACT Skeletal muscle is the most abundant tissue in the human body and is responsible for movement, metabolism, energy production and longevity. Muscle atrophy is a frequent complication of several diseases and occurs when protein degradation exceeds protein synthesis.
Yidi Zhang, Teng Wang, Ziang Wang, Xin'e Shi, Jianjun Jin   +4 more
wiley   +1 more source