Results 161 to 170 of about 65,696 (224)

Access to and unexplored reactivity of nickel-bound 5-membered O- and N-heterocyclic arynes <i>via</i> computational insight. [PDF]

Chem Sci
Pullarat SS, Younis AA, Morais GN, Fitzsimmons MC, Belli RG, Humke JN, Chen S, Roberts CC.   +7 more
europepmc   +1 more source

Catalytic [6 + 3] cycloaddition for the synthesis of medium-sized ring systems: a critical review. [PDF]

RSC Adv
Archna, Kumar G, Chawla PA, Kumar R, Bhargava G.   +4 more
europepmc   +1 more source

Valorization of Tobacco Waste via Catalytic Fast Pyrolysis over Metal-Modified Biochar for Enhanced Aromatic Hydrocarbon Production. [PDF]

ACS Omega
Zhao R, Liu S, Liu Y, Yao Z, Guo Y, Zhu X.   +5 more
europepmc   +1 more source

A Rhodium-Catalyzed Cyclization of Sulfonimidamides and Sulfondiimidamides: Synthesis and Exploration of Chiral Aromatic Heterocycles. [PDF]

J Am Chem Soc
Toth-Williams G, Patten-Trujillo HE, Ahmed YG, DeSnoo W, Kraemer Y, Höppner A, Ning S, Leslie AR, Gao AC, Fettinger JC, Tantillo DJ, Shaw JT.   +11 more
europepmc   +1 more source

SESMic: A Reagent for the Synthesis of 5-Membered Heteroaryl Masked Sulfinates. [PDF]

Org Lett
Chi Y, Chan GH, Moschitto MJ.
europepmc   +1 more source

Gold Single‐Atom Catalysts Enable Selective Shuttle Hydrochlorination of Alkynes

Angewandte Chemie International Edition, EarlyView.
Gold single‐atom catalysts on activated carbon enable heterogeneous shuttle hydrochlorination of terminal alkynes to vinyl chlorides with high chemo‐ and stereo‐selectivity thanks to cooperation between Au(I) sites and the support. The catalytic system combines broad substrate compatibility, simplified separation, and recoverability, paving the way for
Marc‐Eduard Usteri, Eva J. Meeus, Christian Zachau, Seung‐Eun Choi, Aram Bugaev, Milivoj Plodinec, Sharon Mitchell, Bill Morandi, Javier Pérez‐Ramírez   +8 more
wiley   +1 more source

Antitumor and proliferative modulation by N- and O-heterocycles: a comprehensive review of cell growth regulation. [PDF]

Front Chem
Chinibayeva N, Unerbaeva Z, Shepilov D, Berganayeva G, Liu J, Pu X, Nurmahanova A, Zhaksylykova G, Sydykbayeva S, Dyusebaeva M.   +9 more
europepmc   +1 more source

Nucleophilic Ring Opening of Small Size N-Heterocycles in Liquid Sulfur Dioxide

Aziridine and azetidine moieties are important small ring N-heterocycles in organic synthesis due to their biological and pharmacological properties and synthetic potential as a building blocks.
Lugiņina, Jevgeņija, Turks, Māris
core  

Thinking Outside the Binding Site: A Self‐Encapsulating Kinase Inhibitor Remodels Its Pocket to Achieve Selectivity

Angewandte Chemie International Edition, EarlyView.
To make exceptionally effective drugs, thinking “outside the binding site” is required. This work reveals that counterintuitive targeting of a kinase‐conserved region can lead to highly selective binding. Inhibitor discovery coupled to x‐ray crystallography shows that a network of noncanonical interactions and long‐range effects of distant unique amino
Nico J. Seidler, Monica R. MacDonald, Athina A. Moschopoulou, Sahba Cunningham, Tess M. Weber, Nader N. Nasief, Lorenz Mayer, Frederik W. Hacker, Ekaterina Hermann, Mareike B. Möllers, Yuliia Skliarenko, Tahereh Damghani, Abid N. Manzar, Kaly S. Lin, Ramona Rudalska, Marcia I. Goettert, Lars Zender, Daniel Dauch, Michael Forster, Stefan A. Laufer, David E. Heppner   +20 more
wiley   +1 more source

Iodoamidation approach for the construction of isoquinolones and naphthyridinones from <i>o</i>-alkynylaldehydes and (<i>R</i>)-/(<i>S</i>)-phenylglycinol. [PDF]

RSC Adv
Nidhi, Muskan, Shikha, Verma AK.
europepmc   +1 more source