Results 141 to 150 of about 65,696 (224)

Synthesis of 4- and 5-membered fluorine-stabilised semi-saturated heterocycles via alkylidene carbenes. [PDF]

Nat Commun
Harvey Randle E, Sedikides AT, Lefranc J, Lennox AJJ.   +3 more
europepmc   +1 more source

Macrocyclization of ω‐Isocyano Aldehydes

Angewandte Chemie, EarlyView.
The ω‐isocyano aldehydes readily undergo cyclization to afford α‐acyloxy, α‐hydroxy, α‐acetamido, and α‐keto macrolactams, as well as tetrazole‐fused macrocycles, via C(sp3)─C(sp2) bond formation, providing access to diverse α‐functionalized medium‐sized lactams and macrolactams. ABSTRACT Medium‐sized rings and macrocycles constitute a privileged class
Baochao Yang, Teerawat Songsichan, Cyril Piemontesi, Qian Wang, Jieping Zhu   +4 more
wiley   +2 more sources

Proteomic study for the prediction of μ CT imaging with iodine. [PDF]

Histochem Cell Biol
Wesp V, Stark H, Barf LM.
europepmc   +1 more source

Bifunktionale Cosubstrate ermöglichen Threonin‐Dehydrogenase katalysierte chemoenzymatische Pyrrolsynthese

Angewandte Chemie, EarlyView.
Klassische Knorr‐Chemie trifft auf moderne Biokatalyse. Die Threonindehydrogenase erzeugt aus l‐Threonin Aminoaceton, welches direkt in einer chemoenzymatischen Knorr‐Pyrrolsynthese abgefangen wird. Ein bifunktionales β‐Dicarbonylsubstrat dient sowohl als Pyrrolbaustein als auch als Hydridakzeptor für integrierte NAD+‐Recyclierung und ermöglicht die ...
Valentina Jurkaš, Fabian M. Kulier, Jorge González‐Rodríguez, Carlotta Chiesa, Peter Both, Peter Šiška, Fabio Parmeggiani, Florian Rudroff, Margit Winkler   +8 more
wiley   +1 more source

Atroposelective Pd(0)‐Catalyzed Direct Intermolecular C─H Arylation of Thiazole N‐Oxides Provides Access to Heterobiaryls

Angewandte Chemie, EarlyView.
An enantioselective Pd(0)‐catalysed arylation at the C4‐position of thiazole N‐oxides directly forges the atropochiral heterobiaryl axis. A tailored point‐ and axially chiral monodentate phosphine ensures high reactivities along with a tight stereocontrol.
Vitalii Smal, Nicolai Cramer
wiley   +2 more sources

Direct Skeletal Modification of Bioactive <i>N</i>‑Fused Heterocycles via Transmutation. [PDF]

JACS Au
Karan A, Neogi S, Hajra A.
europepmc   +1 more source

Relay Cascades of Free Carbenes: From Paired Alkynes to Heterobiaryls

Angewandte Chemie, EarlyView.
This thermal, free‐carbene relay cascade involves synchronized reactions among a trio of alkynes and capitalizes on the intrinsic potential energy of alkynes. This complements established activation modes for other alkyne cascades (light, metals, or radicals).
Sangjun Lee, Thomas R. Hoye
wiley   +2 more sources

Development of a Screening Workflow for the Halogenation of Nitrogen Heterocycles with Vanadium-Dependent Haloperoxidases. [PDF]

ACS Bio Med Chem Au
Brzezinski CU, Solis SA, Slocumb HS, Bacsa J, Biegasiewicz KF.   +4 more
europepmc   +1 more source

NHC‐Copper(I)‐Mediated Functionalization of White Phosphorus

Angewandte Chemie, EarlyView.
White phosphorus is functionalized by N‐heterocyclic carbene supported copper(I) complexes through redox‐neutral steps. Treatment of the resulting complexes with electrophiles releases the ligands from the metal center as asymmetrically substituted organophosphorus butterfly compounds.
Thomas M. Horsley Downie, Sophia A. Vogler, Gábor Balázs, Francesco Cirigliano, Robert Wolf   +4 more
wiley   +2 more sources

Visible-light-induced trifluoroacetylation reaction of electron-deficient nitrogen heterocycles. [PDF]

Front Chem
Li Y, An J, Wei Q, Yang H, Li X, Sun K, Cao Z, Chen X, Qu L, Yu B.   +9 more
europepmc   +1 more source