Results 121 to 130 of about 65,696 (224)

Access to Unsupported Iminobismuthane and Tetraazabismole Species Enabled by a Rigid and Bulky Organobismuthinidene

Angewandte Chemie, EarlyView.
By employing a sterically bulky monocoordinate bismuthinidene, the synthesis and characterization of the first examples of an unsupported iminobismuthane and tetraazabismole was achieved via reactions with organic azides. The corresponding amines could be accessed by reduction, leading to the regeneration of the Bi(I) compound. Hence, we also highlight
Marcel Potocnik, Kristian L. Mears, Davide Spinnato, Gabriele Deplano, Nils Nöthling, Markus Leutzsch, Maurice van Gastel, Khai‐Nghi Truong, Serena DeBeer, Josep Cornella   +9 more
wiley   +2 more sources

Recent Advances in Indazole-Derived Heterocycles: Synthetic Strategies, Functionalization, and Therapeutic Potential

Journal of Chemistry
Indazole-derived heterocycles have garnered significant attention in recent years due to their versatile chemical structures and wide-ranging biological activities. This review explores the recent progress in the synthesis of indazole-based heterocycles,
Uday V. Bhat, Glanish Jude Martis, Dinesh Chikkanna, Santosh L. Gaonkar   +3 more
doaj   +1 more source

Cobalt‐Catalyzed C─N Bond Formation via Metal‐Hydride Hydrogen Atom Transfer (MHAT)

Angewandte Chemie, EarlyView.
Cobalt‐catalyzed metal‐hydride hydrogen atom transfer (Co‐MHAT) converts simple alkenes into C─N bonds under mild, near‐neutral conditions. A shared Co─H‐initiated radical/organocobalt intermediate is channeled into radical trapping, radical‐polar crossover, or radical ligand transfer, unifying hydroamination, hydroazidation, hydroamidation, and remote
Arman Khosravi, Ming‐Yu Ngai
wiley   +2 more sources

Double Reduction of Ph3B to a Dianionic Borane With a Powerful SrI Intermediate

Angewandte Chemie, EarlyView.
Although dianionic boranes follow the octet rule and are isoelectronic to carbanions or amines, the high electron density combined with the electropositive nature of the B center make them highly unstable species. In this study, we present synthesis and full characterization of a complex in which Ph3B2− is sandwiched between two Sr2+ ions and describe ...
Michael Morasch, Marcel A. Schmidt, Tanuja Tewari, Jens Langer, Sjoerd Harder   +4 more
wiley   +2 more sources

Asymmetric Synthesis of three and four membered ring heterocycles

, 2009
Small heterocyclic rings constitute systems of central importance in theoretical, synthetic organic, bioorganic, andmedicinal chemistry, and in particular aziridines and azirines are very useful and interesting systems as they occur in a number of ...
TOLOMELLI, ALESSANDRA, GENTILUCCI, LUCA, CARDILLO, GIULIANA   +2 more
core  

Catalyst‐Controlled Divergent Strain‐Release Amination and Skeletal Remodeling of Bicyclo[1.1.0]Butanes

Angewandte Chemie, EarlyView.
Catalyst‐controlled nitrene transfer unlocks divergent reactivity of bicyclo[1.1.0]butanes. Rhodium catalysis promotes selective strain‐release amination to access cyclobutene and cyclobutane amino‐acid scaffolds, whereas visible‐light photocatalysis redirects nitrene reactivity toward double amination and skeletal remodeling, providing a complementary
Aksar Ali, Lennard Kloene, Justus Koedel, Yifan Guo, Minakshi Altia, Rene M. Koenigs   +5 more
wiley   +2 more sources

Redshifting TADF Emission With a Bora‐Triptycene Lewis Acid

Angewandte Chemie, EarlyView.
Bathochromic emission shifting of donor–acceptor and multi‐resonant TADF emitters is achieved by adduct formation with a thia‐bora‐triptycene Lewis acid. TADF properties are retained on adduct formation whilst delivering > 100 nm redshift of the emission.
Mathew J. Cross, Emily L. Hanover, Arnaud Osi, Eli Zysman‐Colman, Michael J. Ingleson   +4 more
wiley   +2 more sources

Aktivierung von Metallkomplexen durch Ultraschallwellen für eine gezielte Krebstherapie

Angewandte Chemie, EarlyView.
Ultrasound enables non‐invasive activation of metal‐based therapeutics deep within tumors. Acoustic cavitation can drive sonodynamic reactive oxygen species generation or mechanochemical metal–ligand bond dissociation, enabling controlled release of bioactive payloads.
Félix Grosjean, Nicolás Montesdeoca, Gilles Berger, Johannes Karges   +3 more
wiley   +1 more source

A Mild Disilane‐Enabled Halide‐to‐Deuterium Manifold With D2O for Aryl and Benzylic Halides

Angewandte Chemie, EarlyView.
A broadly applicable Pd‐catalyzed dehalogenative deuteration enables efficient conversion of aryl and benzylic halides with inexpensive deuterium oxide (D2O). The method proceeds under exceptionally mild conditions without strong bases, harsh reductants, or stoichiometric Lewis acid halide scavengers, and tolerates a wide range of functional groups ...
Wenliang Wang, Ryan Parlett, Liam Hornstein, Landon Conklin, Qi Tang, Xiaodong Shi   +5 more
wiley   +2 more sources

Multicomponent Syntheses of glycoside-decorated N-heterocyclic pharmacophores

, 2006
We report in this communication on the synthesis of carbohydrate decorated N-heterocycles, namely dihydropyrimidin-2-ones, dihydropyridines, and azetidin-2-ones, via multicomponent Biginelli, Hantzsch, and Staudinger reactions ...
MASSI, Alessandro, DONDONI, Alessandro
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