Results 201 to 210 of about 468,328 (285)

Synthesis of Nitrogen‐Containing Heterocyclic Scaffolds and Applications in Scaffold Hopping: Development of an Aripiprazole Analog

ChemMedChem, Volume 21, Issue 20, 28 October 2026.
A series of 12 novel fused [6,6] saturated and unsaturated nitrogen bicycles is synthesized in three to five steps and expands the CRAFT library's fragment space. A 2,6‐naphthyridin‐3‐ol core replaces the dihydroquinolinone scaffold of aripiprazole, a scaffold‐hopping strategy.
Temitayo Omowumi Alegbejo Price, Pieterjan Winant, Paulo Eliandro da Silva Júnior, Shaiani Maria Gil de Melo, Pedro Henrique Gobira, Julia Possamai Gimenes, Pedro Tenório Teixeira Fernandes Leite, Vinícius Gonçalves Maltarollo, Gustavo Henrique Goulart Trossini, A. Ganesan, Sâmia Regiane Lourenço Joca, Wim Dehaen, Flavio da Silva Emery   +12 more
wiley   +1 more source

Direct α‐C(sp3)─H Alkylation and Arylation of Ethers Enabled by Carbon Nitride/Nickel Metallaphotoredox Catalysis

ChemSusChem, Volume 19, Issue 20, 28 October 2026.
A recyclable carbon nitride/nickel metallaphotoredox platform enables direct α‐C(sp3)─H arylation and alkylation of ethers, amides, and benzylic substrates under visible light. Broad substrate scope, late‐stage functionalization, five‐cycle photocatalyst reuse, and continuous‐flow translation are demonstrated, while mechanistic studies support ...
Miguel M. de Vries Ibáñez, Nathan G. G. Husy, Elisabetta Inico, Kaan Karaca, Milla Vigliengo, Andrea Olivati, Annamaria Petrozza, Carlo Cavallotti, Gianvito Vilé   +8 more
wiley   +1 more source

Single-Atom Ru on N-Heterocyclic Carbene-Functionalized Hypercrosslinked Polymers for N-Formylation of Amines with CO₂ and H₂. [PDF]

Molecules
Dang L, Gao Y, Wan Y, Li Q, Lei Y.
europepmc   +1 more source

Aqueous‐Phase Processing of Organic Aerosols at the Southern Great Plains: Insights From Integrated Chemical and Microphysical Analyses

Journal of Geophysical Research: Atmospheres, Volume 131, Issue 20, 28 October 2026.
Abstract Aqueous‐phase reactions are hypothesized to be a major pathway for secondary organic aerosol (SOA) formation in humid, cloud‐influenced environments, yet direct observational constraints remain limited. Here we investigated aqueous SOA (aqSOA) formation and evolution during the spring 2016 Holistic Interactions of Shallow Clouds, Aerosols, and
J. Trousdell, W. Jiang, J. Shilling, M. Shrivastava, J. D. Fast, Qi Zhang   +5 more
wiley   +1 more source

Treatment of Azo Dye Wastewater by Anaerobic Membrane Bioreactors: A Review on Process Performance and Mitigation Strategies. [PDF]

Membranes (Basel)
Chen JN, Liu P, Wu H, Li X, Kong Z, Zhang X, Hu Y.   +6 more
europepmc   +1 more source

Stereochemical Control in the Matteson Reaction

Chemistry – A European Journal, Volume 32, Issue 40, 27 October 2026.
The Matteson homologation is a highly versatile method for the stereoselective insertion of carbenoids into boronic esters. Through iterative application of the process, complex chiral molecules can be synthesized. The stereoselectivity of the reaction is determined by a chiral diol incorporated in the boronic ester.
Hae Mo Lee, Christoph Hirschhäuser
wiley   +1 more source

Frontiers in manganese catalysis: a sustainable platform for bond construction and heterocycle synthesis. [PDF]

RSC Adv
Das AK, Sarkar K, Bhattacharjee S, Gajurel S, Dhibar S, Panja SK, Deshmukh SA, Sarkar S.   +7 more
europepmc   +1 more source

N‐Sulfonyl Azalevoglucosan: A Versatile Platform for the Synthesis of Polysubstituted Piperidines

Chemistry – A European Journal, Volume 32, Issue 40, 27 October 2026.
Gain by strain: The synthesis of a levoglucosan analog, in which the pyranose oxygen has been replaced by a nitrogen, allows navigation on the piperidine ring to iteratively install functional groups at C1, C2, C3, C4, and C6 positions using simple experimental protocols with minimal protecting group manipulation.
Dylan Yorga, Jérôme Marrot, Ana Poveda, Nicolas Auberger, Jesús Jiménez‐Barbero, Jérôme Désiré, Yves Blériot   +6 more
wiley   +1 more source

Isolable ArInH2: Double Hydroindation Agent

Chemistry – A European Journal, Volume 32, Issue 40, 27 October 2026.
Stable crystalline monomeric indium dihydride ArInH2 was isolated and completely characterized using effective support of the P,C,P‐pincer ligand (Ar = 2,6‐(tBu2PO)2C6H3). It serves as unparalleled hydroindation agent, thereby extending the family of known hydrometallation process relying on heavy p‐block metals.
Adam Hochmal, Zdeňka Růžičková, Aleš Růžička, Roman Jambor, Milan Erben, Libor Dostál   +5 more
wiley   +1 more source

Red meat consumption: A comprehensive overview of the mechanistic evidence for the effects of oncogenes. [PDF]

Caspian J Intern Med
Mosharkesh E, Roshanravan N.
europepmc   +1 more source