Results 241 to 250 of about 468,328 (285)

Mammalian cell mutagenicity and metabolism of heterocyclic aromatic amines

Mutation Research/Genetic Toxicology, 1991
Heterocyclic aromatic amines are bacterial mutagens which also induce DNA damage in mammalian cells. Damage has been demonstrated using a number of endpoints, including gene mutation, chromosome aberrations, sister-chromatid exchange, DNA-strand breaks, DNA repair and oncogene activation. Although the responses in mammalian cells are weak when compared
H U, Aeschbacher, R J, Turesky
openaire   +2 more sources

Lactoperoxidase-Catalyzed Activation of Carcinogenic Aromatic and Heterocyclic Amines

Chemical Research in Toxicology, 2004
Lactoperoxidase, an enzyme secreted from the human mammary gland, plays a host defensive role through antimicrobial activity. It has been implicated in mutagenic and carcinogenic activation in the human mammary gland. The potential role of heterocyclic and aromatic amines in the etiology of breast cancer led us to examination of the lactoperoxidase ...
Katarzyna M, Gorlewska-Roberts, Candee H, Teitel, Jackson O, Lay, Dean W, Roberts, Fred F, Kadlubar   +4 more
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Detection of heterocyclic aromatic amines in food flavours

Journal of Chromatography A, 1992
Abstract The successful determination of heterocyclic aromatic amines in trace amounts (ng/g) in processed flavours depends largely on the detection sensitivity and selectivity. As part of a systematic study of possibilities for the determination of these mutagenic amines, different detection modes in high-performance liquid chromatography were ...
Rolf Schwarzenbach, Danièle Gubler
openaire   +1 more source

Heterocyclic aromatic amines in fried poultry meat

Zeitschrift f�r Lebensmitteluntersuchung und -Forschung A, 1997
Heterocyclic aromatic amines are mutagenic compounds that are formed during heating of meat and fish. These substances are products of the reaction of creatine with amino acids and carbohydrates. It is recommended that exposure to these probable human carcinogens should be minimised.
M. Murkovic, Manfred Friedrich, Werner Pfannhauser   +2 more
openaire   +1 more source

Chemical analysis and significance of heterocyclic aromatic amines

Zeitschrift f�r Lebensmitteluntersuchung und -Forschung A, 1998
Levels of known heterocyclic amines vary from undetectable in many meats sold in fast food restaurants, to over 10 ng/g for meats prepared in restaurants that cook food to order, to hundreds of nanograms per gram for some meats cooked under certain home or laboratory conditions.
J. S. Felton, Pilar Pais, Cynthia P. Salmon, Mark G. Knize   +3 more
openaire   +1 more source

Difficulties in quantification of heterocyclic aromatic amines in food

2007
[Abstract]
Melo AI, Viegas O, Petisca C, Eça R, Pinho O, Ferreira I   +5 more
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Quantitation of Carcinogenic Heterocyclic Aromatic Amines and Detection of Novel Heterocyclic Aromatic Amines in Cooked Meats and Grill Scrapings by HPLC/ESI-MS

Journal of Agricultural and Food Chemistry, 2005
A tandem solid-phase extraction method was used to isolate carcinogenic heterocyclic aromatic amines (HAAs) from cooked meats. The following 10 HAAs were identified by HPLC/ESI-MS/MS: 2-amino-9H-pyrido[2,3-b]indole (2-AalphaC), 2-amino-3-methyl-9H-pyrido[2,3-b]indole (MeAalphaC), 2-amino-3-methylimidazo[4,5-f]quinoline (IQ), 2-amino-3-methylimidazo[4,5-
Robert J, Turesky, Jason, Taylor, Laura, Schnackenberg, James P, Freeman, Ricky D, Holland   +4 more
openaire   +2 more sources

Aromatic and heterocyclic amines in polymer stabilization

2005
Amines constitute a family of stabilizers protecting plastics and coatings against free radical oxidative degradation and diene based elastomers against both ozonation and oxidation. The respective antioxidant, antifatigue, photo-antioxidant and antiozonant protection of polymers is dependent on the structure of the particular amine.
openaire   +1 more source

HETEROCYCLIC AROMATIC AMINES IN MEAT

Journal of Food Processing and Preservation, 2011
FATIH OZ, MUKERREM KAYA
openaire   +3 more sources

Aromatic and heterocyclic amine metabolism and phenotyping in humans.

Progress in clinical and biological research, 1992
Our method to evaluate acetylator phenotype and N-oxidation phenotype with a single caffeine dose and a single urine specimen collection has enabled us to examine acetylation and N-oxidation by two enzyme systems that have a known genetic polymorphism and are important in aromatic amine metabolism. Based on available data, we have hypothesized patients
N P, Lang, F F, Kadlubar
openaire   +1 more source