Results 1 to 10 of about 3,172,708 (264)

N-heterocyclic germylenes: structural characterisation of some heavy analogues of the ubiquitous N-heterocyclic carbenes [PDF]

, 2019
The X-ray crystal structures of three N-heterocyclic germylenes (NHGes) have been elucidated including the previously unknown 1,3-bis(2,6-dimethylphenyl)diazagermol-2-ylidene (1).
Dodds, Christopher A., Kennedy, Alan R., Spicer, Mark D.   +2 more
core   +2 more sources

Designed Azolopyridinium Salts Block Protective Antigen Pores In Vitro and Protect Cells from Anthrax Toxin [PDF]

, 2013
Background:Several intracellular acting bacterial protein toxins of the AB-type, which are known to enter cells by endocytosis, are shown to produce channels.
A Kronhardt, A Messmer, A Ménard, A Ménard, AA Verveen, AF Kintzer, AM Friedlander, Anika Bronnhuber, AW Artenstein, BA Krantz, C Andersen, C Bachmeyer, C Bachmeyer, C Petosa, Christoph Beitzinger, CT Bahner, D Blöcker, D Blöcker, DB Lacy, EM Nestorovich, EM Nestorovich, F Conti, F Orlik, F Orlik, F Tonello, F Tonello, F Wohnsland, G Hajós, G Timári, G Vitale, György Hajós, H Barth, H Barth, Holger Barth, I Zornetta, J Sun, J Wesche, JA Young, JC Milne, JL Elliott, K Cunningham, KA Bradley, Kerstin Duscha, L Abrami, L Abrami, L Abrami, L Abrami, L Song, Ludger Johannes, M Eigen, M Mock, Markus Huber-Lang, MJ Brown, NS Duesbery, PC Hanna, R Benz, R Benz, R Palkó, R Pellizzari, RJ Collier, RO Blaustein, RO Blaustein, Roland Benz, S Nekolla, SH Leppla, SM Bezrukov, SM Bezrukov, T Neumeyer, T Neumeyer, T Neumeyer, TC Dixon, V Escuyer, VA Karginov, VA Karginov, VA Karginov, Y Singh, Zsuzsanna Riedl   +76 more
core   +2 more sources

Novel applications of the "t-amino effect" in heterocyclic chemistry. Synthesis of a pyrrolo[1,2-a]quinazoline and 5H-pyrrolo[1,2-a][3,1]benzothiazines [PDF]

, 1984
1-(1-Pyrrolidinyl)benzenes substituted with an imino- or an in situ generated thiocarbonyl group in the 2-position rearrange upon heating to quinazoline and benzothiazine derivatives ...
Hamzink, M.R.J., Reinhoudt, D.N., Verboom, W., Visser, R.   +3 more
core   +8 more sources

Microwave-Assisted Synthesis and Evaluation of Antimicrobial Activity of 3-{3-(s-Aryl and s-Heteroaromatic)acryloyl}-2Hchromen-2-one Derivatives [PDF]

, 2010
The exploration of potential utilization of microwaves as an energy source for heterocyclic synthesis was herein investigated using condensation of 3-acetylcoumarin (1) with aromatic and heteroaromatic aldehydes to afford the corresponding aromatic ...
Ajani, Al-Soud, Anderson, Anzari, Curir, DekicÌ, Devi, Gaber, Govori, Gürsoy, Hayes, Hwu, Jayashree, Kontogiorgis, Kostova, Kotali, Lacy, Larsen, Lee, Lewis, Lisgarten, Luszcski, Lévai, Majumdar, Mashelkar, Meteeva, Montagner Souza, Mouri, Neyts, Pivonka, Ragitha, Raviraj, Roma, Russell, Satyanarayana, Saxena, Schobert, Siddiqui, Son, Srinivas, Tamilvanan, Tassies, Tosun, Tran, Venugopala, Yamamoto, Yenjai, Yun   +47 more
core   +1 more source

Revisiting the structure and chemistry of 3(5)-Substituted Pyrazoles [PDF]

, 2019
Pyrazoles are known as versatile scaffolds in organic synthesis and medicinal chemistry, often used as starting materials for the preparation of more complex heterocyclic systems with relevance in the pharmaceutical field.
Alam, Alina Secrieru, Alkorta, Andes, Anwar, Behr, Brown, Castillo, Catalan, Chauhan, Clark, Elguero, Elnagdi, Favre, Fichez, Hall, Horta, Katritzky, Katritzky, Kost, Kumar, Larina, Maria Lurdes Santos Cristiano, Mert, Minkin, Minkin, Mohamed, Nagy, Nimbalkar, Paul Michael O’Neill, Schofield, Simons, Szajda, Taylor, Zerbi   +34 more
core   +2 more sources

Cycloadditions of cyclohexynes and cyclopentyne. [PDF]

, 2014
We report the strategic use of cyclohexyne and the more elusive intermediate, cyclopentyne, as a tool for the synthesis of new heterocyclic compounds. Experimental and computational studies of a 3-substituted cyclohexyne are also described.
Garg, Neil K, Houk, KN, Jiménez-Osés, Gonzalo, McMahon, Travis C, Medina, Jose M   +4 more
core   +2 more sources

Mechanisms linking colorectal cancer to the consumption of (processed) red meat : a review [PDF]

, 2015
Colorectal cancer (CRC) is the third most commonly diagnosed cancer in the world. The vast majority of CRC cases have been linked to environmental causes rather than to heritable genetic changes.
De Smet, Stefaan, Demeyer, Daniël, Mertens, Birgit, Ulens, Michèle   +3 more
core   +2 more sources

Processed Meat and Colorectal Cancer: A Review of Epidemiologic and Experimental Evidence [PDF]

, 2008
Processed meat intake may be involved in the etiology of colorectal cancer, a major cause of death in affluent countries. The epidemiologic studies published to date conclude that the excess risk in the highest category of processed meat-eaters is ...
Corpet, Denis E., Pierre, Fabrice, Santarelli, Raphaëlle L.   +2 more
core   +3 more sources

Alkali-metal-mediated zincation (AMMZn) meets N-heterocyclic carbene (NHC) chemistry : Zn–H exchange reactions and structural authentication of a dinuclear Au(I) complex with a NHC anion [PDF]

, 2013
Merging two evolving areas in synthesis, namely cooperative bimetallics and N-heterocyclic carbenes (NHCs), this study reports the isolation of the first intermediates of alkali-metal-mediated zincation (AMMZn) of a free NHC and a Zn–NHC complex using ...
Aldeco-Perez, Andrikopoulos, Arduengo, III, Arduengo, III, Armstrong, Armstrong, Armstrong, Armstrong, Arnold, Arnold, Arnold, Back, Baillie, Bantu, Bourissou, Clegg, Clegg, Clegg, Conway, Crabtree, de Frémont, Diez-Gonzalez, Flower, Furuyama, Ghadwal, Gomez-Suarez, Guisado-Barrios, Haag, Hashmi, Hashmi, Hashmi, Hashmi, Hashmi, Hashmi, Jimenez-Nunez, Kobayashi, Kronig, Linton, Masuda, Mendoza-Espinosa, Mulvey, Mulvey, Mulvey, Mulvey, Musgrave, Nobuto, Raubnheimer, Rudolph, Rudolph, Schuster, Uchiyama, Wang, Wang, Wang, Wang, Westerhausen   +55 more
core   +1 more source

Red meat and colon cancer : should we become vegetarians, or can we make meat safer ? [PDF]

, 2011
The effect of meat consumption on cancer risk is a controversial issue. However, recent meta-analyses show that high consumers of cured meats and red meat are at increased risk of colorectal cancer.
Corpet, Denis E.
core   +3 more sources