Results 201 to 210 of about 195,223 (291)

<i>De Novo</i> Drug Design, Synthesis, Biological Evaluation, and Structural Examination of Novel Coumarin-Based Pyrimidine Co-Drugs Accompanied by Molecular Docking and DFT Studies. [PDF]

ACS Omega
Naz N, Nazli ZI, Parveen S, Shafiq N.
europepmc   +1 more source

The One‐Step Synthesis of Biologically Active Isochromans from Lignin‐Derived Aromatic Monomers in Tunable Deep Eutectic Solvents

Chemistry – A European Journal, EarlyView.
A straightforward one‐step protocol enables the synthesis of bio‐based and biologically active isochromans through the Oxa‐Pictet cyclization involving diverse aldehydes, including vanillin in combination with lignin‐derivable homovanillyl alcohol, a prominent aromatic platform chemical obtainable via diol‐assisted fractionation of lignocellulose ...
Anjali Kottayi, Anastasiia M. Afanasenko, Antonio A. Castillo‐Garcia, Walid A. M. Elgaher, Jörg Haupenthal, Anna K. H. Hirsch, Katalin Barta   +6 more
wiley   +1 more source

Asymmetric Ring Opening of Oxabicyclic Alkenes: Enhanced Rhodium Catalysis Using Camphor-Derived NHC Ligands Featuring Pyridine Coordination. [PDF]

J Org Chem
Kamzol D, Chen W, Wilhelm R.
europepmc   +1 more source

Photochemistry of Aromatic N‐Oxides in Water Probed by Time‐Resolved X‐ray Absorption Spectroscopy

Chemistry – A European Journal, EarlyView.
Time‐resolved XAS at the nitrogen and oxygen K‐edges is applied to the photorearrangement of two N‐oxides in water. Pyridine N‐oxide rapidly forms the oxaziridine isomer. Pyridazine N‐oxide undergoes ring opening to the diazo compound, without any evidence of intermediates.
Maximilian Paradiz Domínguez, Robby Büchner, Mattis Fondell, Albert M. Brouwer   +3 more
wiley   +1 more source

New isoxazole-based heterocyclic hybrids with dual antimicrobial and antioxidant bioactivity: integrated synthesis, <i>in vitro</i> assessment, and computational exploration. [PDF]

RSC Adv
Arzine A, Ait Assou S, El Bouamri L, Chalkha M, Nakkabi A, Chtita S, M Aljowaie R, A M Aboul-Soud M, El Hassouni M, El Hassouni M, P Giesy J, El Yazidi M.   +11 more
europepmc   +1 more source

Substituent effect on oxidative cyclization of aldehyde thiosemicarbazones with ferric chloride

, 1991
R. Noto, F. Buccheri, G. Cusmano, M. Gruttadauria, G. Werber   +4 more
semanticscholar   +1 more source

Stafib‐2‐CR: an Improved Nanomolar and Selective Inhibitor of the Transcription Factor STAT5b Developed by Conformational Restriction of Stafib‐2

Chemistry – A European Journal, EarlyView.
Conformational restriction strategies to increase the activity and selectivity of the STAT5b inhibitor Stafib‐2 are presented. The best conformationally restricted inhibitor Stafib‐2‐CR has threefold higher activity against STAT5b than Stafib‐2. A cell‐permeable prodrug of Stafib‐2‐CR inhibits phosphorylation of STAT5b in cultured human leukemia cells ...
Theresa Münzel, Angela Berg, Christoph Protzel, Sylvie Schäfer, Alexander Jensen‐Feinhals, Thorsten Berg   +5 more
wiley   +1 more source

A Brønsted-based deep eutectic solvent as a green catalyst for the sustainable one-pot synthesis of 1,2,4,5-tetrasubstituted imidazole derivatives: <i>in vitro</i> cytotoxicity and <i>in silico</i> binding studies on HepG2 cells. [PDF]

RSC Adv
Ngoc Tran TA, Nguyen LD, Nguyen KN, Dang PH, Nguyen HT.   +4 more
europepmc   +1 more source

Synthesis of 1‐Alkynylboronates, 1,1‐Diborylalkenes, and 1,1,1‐Triborylalkanes: Challenges and Opportunities

Chemistry – A European Journal, EarlyView.
ABSTRACT In the field of organoboron chemistry, multi(boronate) esters have emerged as crucial intermediates, with various applications in synthetic chemistry, material technology, and life sciences. This mini‐review discusses recent advancement in the synthesis of these versatile compounds, particularly alkynylboronates, 1,1‐diborylalkenes, and 1,1,1 ...
Son Hoai Doan, Vu Nguyen Tran, Thanh Vinh Nguyen   +2 more
wiley   +1 more source

Sulfone-quinone derivatives: a review on their synthetic methods, properties and applications. [PDF]

RSC Adv
Ghali F, Keshe M.
europepmc   +1 more source