Results 311 to 320 of about 3,269,112 (357)

Heterocyclic compounds as antiviral drugs: Synthesis, structure–activity relationship and traditional applications

Journal of Heterocyclic Chemistry, 2021
A virus outbreak challenges the economic, medical, and public health infrastructure worldwide. More than one virus capable of triggering diseases have been identified per year since 1972, which requires the development of new ways of treatment and ...
G. Santos, L. Martins, B. Bregadiolli, Vitor Fernandes Moreno, L. C. Silva‐Filho, Bruno Henrique Sacoman Torquato Silva   +5 more
semanticscholar   +1 more source

Drugs and Their Mode of Action: A Review on Sulfur-Containing Heterocyclic Compounds

Polycyclic aromatic compounds (Print)
Sulfur-containing heterocyclic compounds have emerged as an important class of bioactive molecules in drug discovery owing to their diverse pharmacological activities and unique modes of action.
Kanchan Kapoor, Navneet Kaur, H. S. Sohal, Manvinder Kaur, Kishanpal Singh, Asim Kumar   +5 more
semanticscholar   +1 more source

Topological Index of Conjugated Heterocyclic Compounds as Their Donor/Acceptor Parameter

Polycyclic aromatic compounds (Print), 2020
The quantum-chemical analysis of donor–acceptor properties of the conjugated heterocyclic compounds is performed. For quantitative estimation of donor/acceptor ability, the topological index φ0 is proposed; it connects with the positions of frontier ...
N. Obernikhina, Marina Kachaeva, Volodymir Shchodryi, Yaroslav Prostota, O. Kachkovsky, V. Brovarets, Z. Tkachuk   +6 more
semanticscholar   +1 more source

Synthesis of heterocyclic compounds through nucleophilic phosphine catalysis.

Chemical Communications, 2020
Nucleophilic phosphine catalysis is a practical and powerful tool for the synthesis of various heterocyclic compounds with the advantages of environmentally friendly, metal-free, and mild reaction conditions.
Yifang Huang, Jianning Liao, Wei Wang, Honglei Liu, Hongchao Guo   +4 more
semanticscholar   +1 more source

Heterocyclic compounds

Proceedings of the Indian Academy of Sciences - Section A, 1938
Coumarius have been prepared from alkyleyclo-hexanone-2-carboxylates andtrans-β-decalone-3-carboxylate by condensing various dihydric and trihydric phenols either in the presence of concentrated sulphuric acid or phosphorus oxychlorid. The Fries'Transformation of the 7-acetoxy-derivatives of the various coumarins has been studied with the purpose of ...
Nazir Ahmad Chowdhry, R. D. Desai
openaire   +2 more sources

Heterocyclic compounds

Proceedings of the Indian Academy of Sciences - Section A, 1958
I. N. Nazarov, A. Sh. Sharifkanov, K. F. Danilova   +2 more
  +7 more sources

A Review on the Antitumor Activity of Various Nitrogenous-based Heterocyclic Compounds as NSCLC Inhibitors.

Mini-Reviews in Medical Chemistry, 2019
At present, cancers have been causing deadly fears to humans and previously incogitable losses to health. Especially, lung cancer is one of the most common causes of cancer-related mortality accounting for approximately 15% of all cancer cases worldwide.
Jiachun Liu, Suresh Narva, Kang Zhou, Wen Zhang   +3 more
semanticscholar   +1 more source

Heterocyclic Compounds Bearing Triazine Scaffold and Their Biological Significance: A Review.

Anti-Cancer Agents in Medicinal Chemistry, 2019
Benzene is a six-membered hydrocarbon ring system if three carbon-hydrogen units of benzene ring are replaced by nitrogen atoms then it forms triazine.
Tarawanti Verma, Manish Sinha, N. Bansal
semanticscholar   +1 more source

Direct Activation of Unmodified Morita-Baylis-Hillman Alcohols through Phosphine Catalysis for Rapid Construction of Three-Dimensional Heterocyclic Compounds.

Organic Letters, 2019
The phosphine-catalyzed tandem annulation reaction of Morita-Baylis-Hillman (MBH) alcohols with azomethine imines has been achieved for the synthesis of biologically important (epoxymethano)-pyrazolo[5,1- b]quinazoline derivatives.
Leijie Zhou, Chunhao Yuan, Yuan Zeng, Qijun Wang, Chang Wang, Min Liu, Wei Wang, Yongjun Wu, B. Zheng, Hongchao Guo   +9 more
semanticscholar   +1 more source

Organocatalytic Asymmetric Synthesis of Spiro-Bridged and Spiro-Fused Heterocyclic Compounds Containing Chromane, Indole, and Oxindole Moieties.

Organic Letters, 2018
Following the reactivity inversion strategy, two different two-step sequences were designed and successfully applied to the asymmetric synthesis of spiro-bridged and spiro-fused heterocyclic compounds, which combined chromane, indole, and oxindole, three
Zhi-Hao You, Yinghan Chen, Yu Tang, Yan-Kai Liu   +3 more
semanticscholar   +1 more source