Results 31 to 40 of about 3,269,112 (357)

Calcium Carbonate Suppresses Haem Toxicity Markers without Calcium Phosphate Side Effect on Colon Carcinogenesis [PDF]

open access: yes, 2010
Red meat intake is associated with increased risk of colorectal cancer. We have previously shown that haemin, haemoglobin and red meat promote carcinogen-induced preneoplastic lesions, aberrant crypt foci, in the colon of rats.
Belbraouet   +14 more
core   +5 more sources

Synthesis of 1,4-Disubstituted Mono and Bis-triazolocarbo-acyclonucleoside Analogues of 9-(4-Hydroxybutyl)guanine by Cu(I)-Catalyzed Click Azide-Alkyne Cycloaddition [PDF]

open access: yes, 2011
A series of novel mono-1,2,3-triazole and bis-1,2,3-triazole acyclonucleoside analogues of 9-(4-hydroxybutyl)guanine was prepared via copper(I)-catalyzed 1,3-dipolar cycloaddition of N-9 propargylpurine, N-1-propargylpyrimidines/as-triazine with the ...
Engels, Joachim W.   +2 more
core   +2 more sources

Alkali-metal-mediated zincation (AMMZn) meets N-heterocyclic carbene (NHC) chemistry : Zn–H exchange reactions and structural authentication of a dinuclear Au(I) complex with a NHC anion [PDF]

open access: yes, 2013
Merging two evolving areas in synthesis, namely cooperative bimetallics and N-heterocyclic carbenes (NHCs), this study reports the isolation of the first intermediates of alkali-metal-mediated zincation (AMMZn) of a free NHC and a Zn–NHC complex using ...
Aldeco-Perez   +55 more
core   +1 more source

Highly Efficient and Diastereoselective Synthesis of New Pyrazolylpyrrolizine and Pyrazolylpyrrolidine Derivates by a Three-Component Domino Process

open access: yesMolecules, 2014
Diastereoselective reactions between 4-formylpyrazoles, N-substituted maleimides and glycine derivates led to new series of pyrazolyldipyrrolo [3,4-a:3',4'-f]pyrrolizines and pyrazolylpyrrolo[3,4-c]pyrroles in good yields.
Jairo Quiroga   +6 more
doaj   +1 more source

Synthesis of New Oxindoles and Determination of Their Antibacterial Properties

open access: yesHeteroatom Chemistry, 2020
A versatile method for the synthesis of new oxindoles was developed by the reaction between substituted isatins and 5-aminopyrazoles. The reaction was carried out at room temperature in ethanol using p-toluenesulfonic acid as the catalyst.
Pablo E. Romo   +4 more
doaj   +1 more source

Traceless Redox-Annulations of Alicyclic Amines

open access: yesSynOpen, 2020
Amines such as 1,2,3,4-tetrahydroisoquinoline undergo redox­-neutral annulations with ortho-(nitromethyl)benzaldehyde. Benzoic­ acid acts as a promoter in these reactions, which involve concurrent amine α-C–H bond and N–H bond functionalization ...
Dillon R. L. Rickertsen   +4 more
doaj   +1 more source

Methods for the synthesis of polyhydroxylated piperidines by diastereoselective dihydroxylation: Exploitation in the two-directional synthesis of aza-C-linked disaccharide derivatives [PDF]

open access: yes, 2005
Background: Many polyhydroxylated piperidines are inhibitors of the oligosaccharide processing enzymes, glycosidases and glycosyltransferases. Aza-C-linked disaccharide mimetics are compounds in which saturated polyhydroxylated nitrogen and oxygen ...
Adam Nelson   +8 more
core   +3 more sources

Asymmetric addition of chiral boron-ate complexes to cyclic iminium ions [PDF]

open access: yes, 2014
Boron-ate complexes derived from enantioenriched secondary benzylic boronic esters and aryl lithiums have been reacted with quinolinium, pyridinium and dihydroisoquinolinium salts to give enantioenriched heterocyclic structures with very high ...
Aggarwal, Varinder K.   +4 more
core   +2 more sources

Heme iron from meat and risk of colorectal cancer: a meta-analysis and a review of the mechanisms involved [PDF]

open access: yes, 2011
Red meat and processed meat intake is associated with a risk of colorectal cancer, a major cause of death in affluent countries. Epidemiological and experimental evidence supports the hypothesis that heme iron present in meat promotes colorectal cancer ...
Bingham   +24 more
core   +4 more sources

Triazine: An Important Building Block of Organic Materials for Solar Cell Application

open access: yesMolecules, 2022
Since the beginning of the 21st century, triazine-based molecules have been employed to construct different organic materials due to their unique optoelectronic properties. Among their applications, photovoltaics stands out because of the current need to
Valeria Dávila Cerón   +2 more
doaj   +1 more source

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