Results 161 to 170 of about 1,436,185 (319)

Beyond $R_0$: Heterogeneity in secondary infections and probabilistic\n epidemic forecasting [PDF]

, 2020
Laurent Hébert‐Dufresne, Benjamin M. Althouse, Samuel V. Scarpino, Antoine Allard   +3 more
openalex   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Can We Interpret Analyses of Etiologic Heterogeneity When Molecular Markers Are Used to Classify Tumors? [PDF]

Cancer Epidemiol Biomarkers Prev
Mooney SJ, Rundle AG.
europepmc   +1 more source

CT-based conventional radiomics and quantification of intratumoral heterogeneity for predicting benign and malignant renal lesions [PDF]

Shuanbao Yu, Yang Yang, Zeyuan Wang, Haoke Zheng, Jinshan Cui, Yonghao Zhan, Junxiao Liu, Peng Li, Yafeng Fan, Wendong Jia, Meng Wang, Bo Chen, Tao Jin, Yuhong Li, Xuepei Zhang   +14 more
openalex   +1 more source

EVALUATING EFFECTS OF MOLECULAR HETEROGENEITY ON THE NON-LINEAR MECHANICAL BEHAVIOR OF EPOXY NETWORKS

, 2021
Zhan H. Yang
openalex   +1 more source

PLATELET HETEROGENEITY [PDF]

British Journal of Haematology, 1984
openaire   +2 more sources

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

An elevational cline in leaf variegation: Testing anti‐herbivory and abiotic heterogeneity hypotheses in maintaining a polymorphism [PDF]

Cierra N. Sullivan, Matthew H. Koski
openalex   +1 more source