Results 141 to 150 of about 1,890,045 (316)
Testing heterogeneity within the euro area. [PDF]
This note estimates several constrained versions of an optimization-based multi-country model to test the sources of heterogeneity within the euro area.
Sahuc, J-G., Jondeau, E.
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Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Random Covariance Heterogeneity in Discrete Choice Models [PDF]
The area of discrete choice modelling has developed rapidly in recent years. In particular, continuing refinements of the Generalised Extreme Value (GEV) model family have permitted the representation of increasingly complex patterns of substitution and ...
Stephane Hess, John Polak, Denis Bolduc
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Testing for Proportional Hazards with Unrestricted Univariate Unobserved Heterogeneity [PDF]
, 2009 We develop tests of the proportional hazards assumption, with respect to a continuous covariate, in the presence of unobserved heterogeneity with unknown distribution at the individual observation level.
Bhattacharjee, Arnab +1 more
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Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Accounting for the Heterogeneity in Retirement Wealth [PDF]
This paper studies a quantitative dynamic general equilibrium life-cycle model where parents and their children are linked by bequests, both voluntary and accidental, and by the transmission of earnings ability.
Fang (Annie) Yang
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Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Unemployment Duration among Immigrants and Natives: Unobserved Heterogeneity in a Multi-Spell Duration Model [PDF]
This paper studies whether the unemployment dynamics of immigrants differ from those of natives, paying special attention to the impact of accounting for unobserved heterogeneity among individuals.
Raquel Carrasco +1 more
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Hereditary Predisposition to Acute Myeloid Leukemia in Older Adults
HemaSphere, 2021 Laurène Fenwarth +11 more
doaj +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source