Results 41 to 50 of about 38,755 (208)

Differential Conformational Dynamics Encoded by the Linker between Quasi RNA Recognition Motifs of Heterogeneous Nuclear Ribonucleoprotein H

Journal of the American Chemical Society, 2018
Members of the heterogeneous nuclear ribonucleoprotein (hnRNP) F/H family are multipurpose RNA binding proteins that participate in most stages of RNA metabolism. Despite having similar RNA sequence preferences, hnRNP F/H proteins function in overlapping
Srinivasa R. Penumutchu, Liang-Yuan Chiu, J. Meagher, Alexandar L. Hansen, J. Stuckey, B. Tolbert   +5 more
semanticscholar   +1 more source

Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing

Advanced Science, EarlyView.
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale, Marie Celine Lefevre, Alessio Carmignani, Maria Cristina Ceccarelli, Matteo Battaglini, Attilio Marino, Gianni Ciofani   +6 more
wiley   +1 more source

APRIL is a novel clinical chemo-resistance biomarker in colorectal adenocarcinoma identified by gene expression profiling [PDF]

, 2009
Highly accessed articlePeer ...
Samuel Leslie M, McKinlay, Aileen, Aly, Emad, Binnie, Norman, Semple, Scott, Semple, Scot, Elaina SR Collie-Duguid, Semple Scot, Fiona Gilbert, Wang Weiguang, O'Kelly Terrence, Murray, Graeme I., Scot Semple, Binnie Norman, Samuel, Leslie M., Aly Emad, Graham MacDonald, Emad Aly, Collie-Duguid Elaina SR, Petty, Russell D, Terrence O'Kelly, Loudon, Malcolm, Norman Binnie, Wang, Weiguang, Samuel, Leslie M, Collie-Duguid, Elaina S. R., Gilbert Fiona, Russell D Petty, MacDonald, Graham, Collie-Duguid, Elaina S R, McKinlay Aileen, Murray Graeme I, Gilbert, Fiona, Loudon Malcolm, Malcolm Loudon, MacDonald Graham, O'Kelly, Terrence, Leslie M Samuel, Petty, Russell David, Petty, Russell D., Graeme I Murray, Aileen McKinlay, Petty Russell D, Weiguang Wang, Murray, Graeme I   +44 more
core   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source

Homology of a Maturase to the Heart of the Nuclear Spliceosome [PDF]

, 2021
Structural and biochemical evidence links group II introns as evolutionary precursors of nuclear introns. The spliceosome binds and excises nuclear introns. Maturases are prokaryotic enzymes that aid group II intron excision.
Becker, Isabella
core  

Identification of reference genes for gene expression assessment in Avena sativa under biotic stress triggered by Blumeria graminis

Scientific Reports
A repeatable and reliable reverse transcription quantitative PCR (RT-qPCR) experiment depends upon proper reference genes (RGs) selection. This study aims to examine the expression stability of nine candidate RGs for the Avena sativa – Blumeria graminis ...
Sylwia Sowa, Joanna Toporowska, Edyta Paczos-Grzęda   +2 more
doaj   +1 more source

Scalable Engineering of Bio‐Manufactured Extracellular Vesicles for Selective Delivery in Ovarian Cancer Patient‐Derived Models

Advanced Science, EarlyView.
Engineered extracellular vesicles displaying Ephrin‐B2 selectively target Ephrin‐B4–expressing ovarian cancer cells, enabling precise delivery in patient‐derived models. This scalable bio‐manufacturing platform reveals a versatile strategy to exploit Ephrin signaling for highly specific therapeutic payload delivery and motivates exploration of tailored
Nihar Godbole, Andrew Lai, Alexander Quinn, Marianne Gillard, Dominic Guanzon, Katherin Scholz‐Romero, Alexis Salas‐Burgos, Bastián Lillo Dapremont, Rohan Lourie, Naven Chetty, Richard Lobb, Kate Beecher, Amy E. McCart Reed, Kaltin Ferguson, Biao Sun, Yaowu He, John D. Hooper, Carlos Salomon   +17 more
wiley   +1 more source

Mechanisms of multidrug resistance in bladder cancer: the role of the nuclear membrane [PDF]

, 2007
Multidrug resistance (MDR) describes the phenomenon whereby cancer cellsexposed to a single cytotoxic drug develop cross resistance to numerous otherstructurally unrelated chemotherapeutics.
Featherstone, Jonathan Mark
core  

S-Nitrosylation of Heterogeneous Nuclear Ribonucleoprotein A/B Regulates Osteopontin Transcription in Endotoxin-stimulated Murine Macrophages*

Journal of Biological Chemistry, 2004
Osteopontin (OPN) is a highly hydrophilic and negatively charged sialoprotein of ∼298 amino acids that contains a Gly-Arg-Gly-Asp-Ser sequence. It is a secreted protein with diverse regulatory functions, including cell adhesion and migration, tumor ...
Chengjiang Gao, Hongtao Guo, Junping Wei, Z. Mi, P. Wai, P. Kuo   +5 more
semanticscholar   +1 more source

The RNA‐Binding Protein PARN Remodeled 3′ UTR Structure Defines Poly(A)‐Loading Sites to Mediate Immunoglobulin Homeostasis

Advanced Science, EarlyView.
ABSTRACT Class Switch Recombination (CSR) is essential for generating high‐affinity antibody isotypes from IgM during adaptive humoral responses. Despite well‐established roles for various transcription factors, whether CSR is subject to dedicated post‐transcriptional control represents a significant gap in knowledge.
Siyuan Sun, Chen Yang, Xiaoyu Wang, Naijing Hu, Shengyao Zhang, Xinchun Li, Yu Chen, Jianan Zhai, Xiangfeng Tang, Wei Lu, Chenxu Lu, Changchang Cao, Weiru Yu, Wenhao Wu, Xiaonan Nie, Fengchao Wang, Bing Fang, Fazheng Ren, Yixuan Li, Juan Chen   +19 more
wiley   +1 more source