Results 81 to 90 of about 432,033 (303)
Improving Tatonnement Methods for Solving Heterogeneous Agent Models [PDF]
This paper modifies standard block Gauss-Seidel iterations used by tatonnement methods for solving large scale deterministic heterogeneous agent models.
Ludwig, Alexander
core
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
MethodsX, 2018 Modelers often apply analytical (differential equation-based) epidemic models that mostly characterize the behavior of the network compartments with passage of time.
ChukwuNonso Nwokoye, Ikechukwu Umeh
doaj +1 more source
Beyond DSGE Models: Toward an Empirically Based Macroeconomics [PDF]
This paper argues that macro models should be as simple as possible, but not more so. Existing models are “more so” by far. It is time for the science of macro to step beyond representative agent, DSGE models and focus more on alternative heterogeneous ...
Alan Kirman +4 more
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Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Behavioral and Topological Heterogeneities in Network Versions of Schelling’s Segregation Model
ComplexityAgent-based models of residential segregation have been of persistent interest to various research communities since their origin with James Sakoda and popularization by Thomas Schelling.
Will Deter, Hiroki Sayama
doaj +1 more source
Frontiers in Endocrinology, 2019 The introduction of ultra-precision targeted therapy has become a significant advancement in cancer therapeutics by creating treatments with less off target effects.
Elizabeth R. McGonagle +2 more
doaj +1 more source
Labor-Market Heterogeneity, Aggregation, and the Policy-(In)variance of DSGE Model Parameters [PDF]
Data from a heterogeneous-agents economy with incomplete asset markets and indivisible labor supply are simulated under various fiscal policy regimes and an approximating representative-agent model is estimated.
Frank Schorfheide +2 more
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Heterogeneous Agent Models in Economics and Finance [PDF]
SSRN Electronic Journal, 2005 This chapter surveys work on dynamic heterogeneous agent models (HAMs) in economics and finance. Emphasis is given to simple models that, at least to some extent, are tractable by analytic methods in combination with computational tools. Most of these models are behavioral models with boundedly rational agents using different heuristics or rule of ...
openaire +2 more sources
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source