Results 51 to 60 of about 143,250 (293)

Chiral surfaces self-assembling in one-component systems with isotropic interactions [PDF]

, 2012
We show that chiral symmetry can be broken spontaneously in one-component systems with isotropic interactions, i.e. many-particle systems having maximal a priori symmetry.
E. Edlund, E. Eliel, E. N. Jacobsen, G. Blaschke, G. B. Folland, M. Nilsson Jacobi, O. Lindgren   +6 more
core   +2 more sources

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Ni–Ru-containing mixed oxide-based composites as precursors for ethanol steam reforming catalysts: Effect of the synthesis methods on the structural and catalytic properties

Open Chemistry, 2021
Ethanol steam reforming catalyst’s precursors, i.e., nanocomposites of complex oxides with the general formula [Pr0.15Sm0.15Ce0.35Zr0.35O2 + LaMn0.45Ni0.45Ru0.1O3] (1:1 by mass), were synthesized by three different methods.
Naurzkulova Symbat Muratbekovna, Arapova Marina Vasilievna, Ishchenko Arcady Vladimirovich, Krieger Tamara Andreevna, Saraev Andrei Aleksandrovich, Kaichev Vasilii Vasilievich, Rogov Vladimir Alekseevich, Krasnov Aleksei Vyacheslavovich, Massalimova Bakytgul Kabykenovna, Sadykov Vladislav Aleksandrovich   +9 more
doaj   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

The Effect of the NbVO_x Synthesis Protocol on the Extractive Catalytic Oxidative Desulfurization of Dibenzothiophene

Molecules
NbVOx mixed oxides were synthesized, characterized, and evaluated as catalysts for the extractive catalytic oxidative desulfurization (ECODS) of dibenzothiophene (DBT) using acetonitrile as a solvent.
Katarzyna Stawicka, Julia Gajewska, Maria Ziolek, Maciej Trejda   +3 more
doaj   +1 more source

Mixed-metal MIL-100(Sc,M) (M=Al, Cr, Fe) for Lewis acid catalysis and tandem C−C bond formation and alcohol oxidation [PDF]

, 2014
The authors thank Johnson Matthey and the EPSRC for an Industrial CASE award to L.M. We gratefully acknowledge the IAESTE UK for a scholarship to B.E.
Acerbi, Nadia, Anderson, Amanda Elizabeth, Ashbrook, Sharon Elizabeth, Clarke, Matthew L., Daniels, Luke, Ehrlichova, Barbora, Mitchell, Laura, Seymour, Valerie Ruth, Walton, Richard, Williamson, Patrick, Wright, Paul Anthony   +10 more
core   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Review of catalytic systems and thermodynamics for the Guerbet condensation reaction and challenges for biomass valorization [PDF]

, 2015
The Guerbet condensation reaction is an alcohol coupling reaction that has been known for more than a century. Because of the increasing availability of bio-based alcohol feedstock, this reaction is of growing importance and interest in terms of value ...
Gabriels, D, Hernández Enciso, Willinton Yesid, Sels, B, Van Der Voort, Pascal, Verberckmoes, An   +4 more
core   +2 more sources

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Polyoxometalate (POM)-layered double hydroxides (LDH) composite materials: design and catalytic applications [PDF]

, 2017
Layered double hydroxides (LDHs) are an important large class of two-dimensional (2D) anionic lamellar materials that possess flexible modular structure, facile exchangeability of inter-lamellar guest anions and uniform distribution of metal cations in ...
Li, Tengfei, MIras, Haralampos N., Song, Yu-Fei   +2 more
core   +1 more source