Results 71 to 80 of about 1,107,746 (301)
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
FEBS Open Bio, EarlyView.Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
Laws Of Heterogeneous Catalysis
, 2022 Based on the generalization of experimental and theoretical studies in the field of catalysis, three basic laws of heterogeneous catalysis were discovered.
Kosinov, M. (Mykola) +1 more
core
Adenosine triphosphate as a modulator of protein interactions and stability
FEBS Open Bio, EarlyView.ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley +1 more source
Small ScienceThe sluggish hydrogen evolution reaction (HER) kinetics in alkaline media, primarily attributed to the additional water dissociation step, has led to a significant activity gap between acidic and alkaline conditions.
Ashwani Kumar +3 more
doaj +1 more source
Homogeneous Catalysis in Heterogeneous Nanoreactors
, 2012 Homogeneous Catalysis in Heterogeneous ...
李灿
core
Preparation of catalysts from microemulsions and their applications in heterogeneous catalysis
, 2004 Microemulsions have a wide range of applications from oil recovery to synthesis of nanoparticles. The first implementation of water-in-oil (w/o) microemulsions for synthesis of nanoparticles was introduced in 1982 and concerns nanoparticles of noble ...
Rojas, Sergio, +3 more
core +1 more source
Protocol for quantifying miRNA trafficking across the endosomal membrane
FEBS Open Bio, EarlyView.An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
Heterotropic regulation and negative homotropic cooperativity
FEBS Open Bio, EarlyView.We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
Plastron-mediated direct H2O2 synthesis
Nature CommunicationsGas-liquid-solid catalytic reactions are ubiquitous in the chemical industry and environmental chemistry. The efficacy of these reactions is constrained by the inherently low solubility of gases in liquids and poor mass transfer of reactants/products to ...
Kang Wang +8 more
doaj +1 more source
The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity
FEBS Open Bio, EarlyView.Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav +4 more
wiley +1 more source