Results 61 to 70 of about 323,439 (311)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Catastrophic Rupture Induced Damage Coalescence in Heterogeneous Brittle Media [PDF]

open access: yes, 2004
In heterogeneous brittle media, the evolution of damage is strongly influenced by the multiscale coupling effect. To better understand this effect, we perform a detailed investigation of the damage evolution, with particular attention focused on the ...
汪海英   +4 more
core  

Modeling cell movement in anisotropic and heterogeneous network tissues [PDF]

open access: yes, 2007
Cell motion and interaction with the extracellular matrix is studied deriving a kinetic model and considering its diffusive limit. The model takes into account of chemotactic and haptotactic effects, and obtains friction as a result of the interactions ...
A. Chauviere   +6 more
core   +1 more source

Heterogeneous Reactions of Epoxides in Acidic Media [PDF]

open access: yesThe Journal of Physical Chemistry A, 2012
Epoxides have recently been identified as important intermediates in the gas phase oxidation of hydrocarbons, and their hydrolysis products have been observed in ambient aerosols. To evaluate the role of epoxides in the formation of secondary organic aerosols (SOA), the kinetics and mechanism of heterogeneous reactions of two model epoxides, isoprene ...
Vinita, Lal   +5 more
openaire   +2 more sources

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

On the measurement of solute concentrations in 2-D flow tank experiments [PDF]

open access: yes, 2007
In this study we describe and compare photometric and resistivity measurement methodologies to determine solute concentrations in porous media flow tank experiments.
E. Meier   +11 more
core   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Effective Surface and Boundary Condition for Heterogeneous Salt Media with Insoluble Material [PDF]

open access: yes, 2013
Effective Surface and Boundary Condition for Heterogeneous Salt Media with Insoluble ...
Veran-Tissoires, Stéphanie   +2 more
core  

A class of evolutionary operators and its applications to electroseismic waves in anisotropic, inhomogeneous media [PDF]

open access: yes, 2011
In the framework of a comprehensive theory for a new class of evolutionary problems wellposedness of associated initial boundary value problems is considered.
Rainer Picard   +3 more
core   +1 more source

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