Results 81 to 90 of about 321,248 (311)

Dynamics of traveling pulses in heterogeneous media [PDF]

open access: yesChaos: An Interdisciplinary Journal of Nonlinear Science, 2007
One of the fundamental issues of pulse dynamics in dissipative systems is clarifying how the heterogeneity in the media influences the propagating manner. Heterogeneity is the most important and ubiquitous type of external perturbation. We focus on a class of one-dimensional traveling pulses, the associated parameters of which are close to drift and/or
Nishiura, Yasumasa   +3 more
openaire   +4 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Machine Learning-Empowered Real-Time Acoustic Trapping: An Enabling Technique for Increasing MRI-Guided Microbubble Accumulation

open access: yesSensors
Acoustic trap, using ultrasound interference to ensnare bioparticles, has emerged as a versatile tool for life sciences due to its non-invasive nature. Bolstered by magnetic resonance imaging’s advances in sensing acoustic interference and tracking drug ...
Mengjie Wu, Wentao Liao
doaj   +1 more source

Characterization of Bimolecular Reactive Transport in Heterogeneous Porous Media

open access: yes, 2016
We characterize the role of preferential pathways in controlling the dynamics of bimolecular reactive transport in a representative model of a heterogeneous porous medium.
GUADAGNINI, ALBERTO   +4 more
core   +1 more source

Upscaling multi-component two-phase flow in porous media with partitioning coefficient [PDF]

open access: yes, 2011
This paper deals with the upscaling of multicomponents two-phase flow in porous media. In this paper, chemical potential equilibrium at the interface between both phases is assumed to be described by a linear partitioning relationship such as Raoult or ...
Quintard, Michel   +5 more
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Scaling of Imbibition Front Dynamics in Heterogeneous Porous Media

open access: yesGeophysical Research Letters, 2020
We report a quantitative study on the dynamics of countercurrent imbibition in fractured rock samples with the application of CO2 geosequestration, as the rock matrix is saturated with CO2 and brine exists in the adjacent microfracture. Direct pore‐scale
Sahar Bakhshian   +3 more
doaj   +1 more source

Thermodynamically consistent modeling of two-phase incompressible flows in heterogeneous and fractured media

open access: yesOil & Gas Science and Technology, 2020
Numerical modeling of two-phase flows in heterogeneous and fractured media is of great interest in petroleum reservoir engineering. The classical model for two-phase flows in porous media is not completely thermodynamically consistent since the energy ...
Gao Huicai   +3 more
doaj   +1 more source

Tailorable Aqueous-Media Synthesis of Heterogeneous Copper Nanoparticles Hybrids and Application in Selective Oxidation of Benzene

open access: yes, 2019
Novel heterogeneous nanocatalysts has been synthesized in aqueous media at multimilligram scale for highly selective direct oxidation of benzene to phenol in aqueous media. The synthesis of a novel biohybrids containing copper nanoparticles (CuNPs) by
Jose M, Palomo   +2 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

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