Results 71 to 80 of about 3,391,346 (320)
Lysosomal storage disorders (LSDs) constitute a heterogeneous group of approximately 50 genetic disorders. LSDs diagnosis is challenging due to variability in phenotype penetrance, similar clinical manifestations, and a high allelic heterogeneity.
Diana Rojas Málaga +8 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Recursos naturales, diversificación y crecimiento regional en el Perú
Basado en la red de espacio de productos de exportación, este trabajo muestra las principales características de la composición de productos de exportación del Perú y sus regiones.
Mario D. Tello
doaj
Modelling Canopy Temperature of Crops With Heterogeneous Canopies Grown Under Solar Panels
With global warming and the increase of heatwaves frequencies, it has become urgent to protect crops. Agrivoltaic systems tackle this issue by shading plants with photovoltaic panels to lower the temperature of canopies.
Jérôme Chopard +3 more
doaj +1 more source
Intelligent Real-Time Photovoltaic Panel Monitoring System Using Artificial Neural Networks
Photovoltaic panels system is becoming a popular choice as an alternative source of energy. This system comes with many challenges. To harness reliable energy efficiently, the photovoltaic panels system must remain in its best condition.
Sufyan Samara, Emad Natsheh
doaj +1 more source
Aggregated Markov Models of a Heterogeneous Population of Photovoltaic Panels [PDF]
We present a new framework for aggregated quantitative modelling of a heterogeneous population of photovoltaic panels. We are interested in the behaviour of photovoltaic panels as electric power sources, and in an aggregated model that can capture how such a population behaves when connected to the power grid.
Peruffo, A +3 more
openaire +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
HS Solar Energy Company Inc. in Sejong city, Korea, has a big problem on how to monitor heterogeneous inverters with different protocols. Still a current photovoltaic power plant with different inverters, it has attracted significant attention to its ...
Woo Sung Jang +4 more
doaj +1 more source
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source

