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Neutralization Activity against SARS-CoV-2 Variants after Booster Vaccination in Populations without COVID-19: A Meta-Analysis

Vaccines, 2022
A number of SARS-CoV-2 variants that have evolved to have significant immune escape have emerged worldwide since the COVID-19 outbreak. The efficacy of prime vaccination is waning with the evolution of SARS-CoV-2, and the necessity of booster doses is ...
Haoyue Cheng, Zhicheng Peng, Shuting Si, Xialidan Alifu, Haibo Zhou, Peihan Chi, Yan Zhuang, Minjia Mo, Yunxian Yu   +8 more
doaj   +1 more source

The Effects of Heterologous Immunization with Prime-Boost COVID-19 Vaccination against SARS-CoV-2

Vaccines, 2021
Coronavirus Disease 2019 (COVID-19) pandemic, which is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has become the global challenge. Reaching global herd immunity will help end the COVID-19 pandemic.
Tzu-Chuan Ho, Yi-Ming Arthur Chen, Hung-Pin Chan, Chin-Chuan Chang, Kuo-Pin Chuang, Che-Hsin Lee, Cheng-Hui Yuan, Yu-Chang Tyan, Ming-Hui Yang   +8 more
doaj   +1 more source

Antibodies Induced by Homologous or Heterologous Inactivated (CoronaVac/BBIBP-CorV) and Recombinant Protein Subunit Vaccines (ZF2001) Dramatically Enhanced Inhibitory Abilities against B.1.351, B.1.617.2, and B.1.1.529 Variants

Vaccines, 2022
Safe and effective vaccines for Corona Virus Disease 2019 (COVID-19) can prevent the virus from infecting human populations and treat patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
Xuesong Xu, Yi Hong, Erjing Chen, Yaping Wang, Biao Ma, Jiali Li, Wei Su, Yuxin Zhou, Mingzhou Zhang   +8 more
doaj   +1 more source

Immune Response of a Heterologous mRNA-1273 Second-Dose Immunization after a First Dose of ChadOx1 against SARS-CoV-2: A Cross-Sectional Study

Vaccines, 2022
Heterologous vaccination regimens could contribute to broadening vaccination coverage. To date, there is little evidence on the effectiveness of a combination of adenoviral COVID-19 vaccines with a second dose of mRNA vaccines.
Beatrice Albanesi, Alessandro Godono, Rosanna Irene Comoretto, Elena Casabona, Giuliano Curoso, Massimiliano Victor Leone, Nicolò Milanesio, Ilenia Mirra, Giulia Montrucchio, Fabrizia Pittaluga, Rossana Cavallo, Marco Clari, Catalina Ciocan   +12 more
doaj   +1 more source

Alloimmunity to Class 2 Human Leucocyte Antigens May Reduce HIV-1 Acquisition – A Nested Case-Control Study in HIV-1 Serodiscordant Couples

Frontiers in Immunology, 2022
Enveloped viruses, including the Human Immunodeficiency Virus-1 (HIV), incorporate host proteins such as human leucocyte antigens (HLA) into their envelope.
Melinda S. Suchard, Melinda S. Suchard, Neil Martinson, Neil Martinson, Susan Malfeld, Debbie de Assis Rosa, Romel D. Mackelprang, Romel D. Mackelprang, Jairam Lingappa, Jairam Lingappa, Xuanlin Hou, Helen Rees, Sinead Delany-Moretlwe, Hadassa Goldfein, Heena Ranchod, Heena Ranchod, David Coetzee, Kennedy Otwombe, Kennedy Otwombe, Lynn Morris, Lynn Morris, Caroline T. Tiemessen, Caroline T. Tiemessen, Dana M. Savulescu   +23 more
doaj   +1 more source

Self-reported adverse events after 2 doses of COVID-19 vaccine in Korea [PDF]

Epidemiology and Health, 2022
OBJECTIVES In Korea, a national coronavirus disease 2019 (COVID-19) vaccination program was implemented, including 4 vaccines against COVID-19. A text messaging-based survey, in addition to a passive adverse event reporting system, was launched to ...
Yunhyung Kwon, Insob Hwang, Mijeong Ko, Hyungjun Kim, Seontae Kim, Soon-Young Seo, Enhi Cho, Yeon-Kyeng Lee   +7 more
doaj   +1 more source

Evaluation of the Safety and Immunogenicity of Fractional Intradermal COVID-19 Vaccines as a Booster: A Pilot Study

Vaccines, 2022
Intradermal vaccination using fractional dosages of the standard vaccine dose is one strategy to improve access to COVID-19 immunization. We conducted a pilot study in healthy adults in Thailand to evaluate the safety and immunogenicity of intradermal ...
Suvimol Niyomnaitham, Somruedee Chatsiricharoenkul, Zheng Quan Toh, Sansnee Senawong, Chatkamol Pheerapanyawaranun, Supaporn Phumiamorn, Paul V. Licciardi, Kulkanya Chokephaibulkit   +7 more
doaj   +1 more source

Immunogenicity and Safety of Homologous and Heterologous Prime–Boost Immunization with COVID-19 Vaccine: Systematic Review and Meta-Analysis

Vaccines, 2022
A prime–boost strategy of COVID-19 vaccines brings hope to limit the spread of SARS-CoV-2, while the immunogenicity of the vaccines is waning over time. Whether a booster dose of vaccine is needed has become a widely controversial issue.
Haoyue Cheng, Zhicheng Peng, Shuting Si, Xialidan Alifu, Haibo Zhou, Peihan Chi, Yan Zhuang, Minjia Mo, Yunxian Yu   +8 more
doaj   +1 more source

Heterologous production of chondroitin

Biotechnology Reports, 2022
Chondroitin sulfate (CS) is a glycosaminoglycan with a broad range of applications being a popular dietary supplement for osteoarthritis. Usually, CS is extracted from animal sources. However, the known risks of animal products use have been driving the search for alternative methods and sources to obtain this compound.
Márcia R. Couto, Joana L. Rodrigues, Lígia R. Rodrigues   +2 more
openaire   +4 more sources

Aerosol Inhalation of Chimpanzee Adenovirus Vectors (ChAd68) Expressing Ancestral or Omicron BA.1 Stabilized Pre–Fusion Spike Glycoproteins Protects Non–Human Primates against SARS-CoV-2 Infection

Vaccines, 2023
Current COVID-19 vaccines are effective countermeasures to control the SARS-CoV-2 virus pandemic by inducing systemic immune responses through intramuscular injection.
Shen Wang, Mian Qin, Long Xu, Ting Mu, Ping Zhao, Bing Sun, Yue Wu, Lingli Song, Han Wu, Weicheng Wang, Xingwen Liu, Yanyan Li, Fengmei Yang, Ke Xu, Zhanlong He, Michel Klein, Ke Wu   +16 more
doaj   +1 more source