Results 121 to 130 of about 196,489 (314)

Minimizing the enzyme dosage for ethanol production from cellulose‐rich bagasse residues after furfural production

open access: yesBiofuels, Bioproducts and Biorefining, EarlyView.
Abstract Through consolidated bioprocessing, cellulosic ethanol production from sugarcane bagasse residues emanating from furfural production (furfural residues, FRs) may offer substantial cost reductions compared with conventional pretreatment–hydrolysis–fermentation of lignocelluloses. Furfural residues have a high enzymatic digestibility and require
Godrick E. Bunga   +4 more
wiley   +1 more source

Biomanufacturing Potential of Streamlined Cells

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT A series of Escherichia coli streamlined strains was developed by removing the expression of genes encoding extracellular structures and unessential enzymes. The streamlined strains exhibited improved metabolic performance, including lower overflow metabolism and ATP maintenance coefficient, as well as a higher growth rate, compared to their ...
Alvaro R. Lara   +10 more
wiley   +1 more source

Recombinant Expression and Bioprocess Optimization of Priestia megaterium α‐Amylase and Its Impact on Dough Fermentation Efficiency

open access: yesChemistry &Biodiversity, EarlyView.
This study presents a scalable strategy for producing Priestia megaterium α‐amylase (PmAmy) via fed‐batch fermentation, optimizing the biomass/IPTG ratio to enhance yield. With an activity of 67.7 U mL−1 at 22.3 g L−1 biomass, PmAmy demonstrated 99% efficiency in dough fermentation, highlighting its industrial potential as a sustainable baking enzyme .
Atacan Erdem   +3 more
wiley   +1 more source

In Vivo Biosynthesis and Direct Incorporation of Noncanonical Amino Acids into Proteins

open access: yesChemBioChem, EarlyView.
This review evaluates engineered (semi)autonomous cell systems for the biosynthesis and incorporation of noncanonical amino acids (ncAAs) into proteins. While semi‐autonomous cells convert supplied precursors into ncAAs autonomous cells integrate biosynthetic pathways that produce these building blocks intracellularly.
Jan Hendrik Illies   +2 more
wiley   +1 more source

Dominant‐Negative Effects of p53 R337 Variants in Li–Fraumeni Syndrome: Impact on Tetramer Formation and Transcriptional Activity

open access: yesChemBioChem, EarlyView.
Hetero‐tetramer dysfunction: Li–Fraumeni syndrome (LFS) is a hereditary cancer predisposition caused by mutations in the TP53 gene encoding the tumor suppressor p53. It is shown that p53 variants R337C and R337H, found in LFS, impair wild‐type (WT) p53 function by forming heterotetramers with reduced transcriptional activity.
Rui Kamada   +6 more
wiley   +1 more source

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