Results 161 to 170 of about 196,489 (314)

Development of a Promising Bivalent Vaccine Against Klebsiella pneumoniae Based on Glycoengineered GMMA (geGMMA)

open access: yesExploration, EarlyView.
Multidrug‐resistant Klebsiella pneumoniae poses a significant threat as a nosocomial pathogen, with no current licensed vaccines available. This study used a mutant E. coli strain expressing exogenous polysaccharides (from K. pneumoniae) to establish glycoengineered generalized modules for membrane antigens (geGMMA) vaccine platform, which demonstrated
Jingqin Ye   +13 more
wiley   +1 more source

Personalized Cancer Immunotherapy Boosted by cGAS‐STING‐Targeted Nanovaccines in Combination With Nutrient Modulation

open access: yesExploration, EarlyView.
The engineered bacteria (2'3'‐cGAMP@E.coli) is designed to synthesize intracellular 2'3'‐cGAMP, enabling the assembly of personalized nanovaccines (nECTs) through a bioconjugation with autologous tumor antigens, circumventing elaborate chemical production processes. The therapeutic impact of nECTs is significantly amplified when combined with a fasting‐
Wenping Huang   +7 more
wiley   +1 more source

Development of clinical immunity to Plasmodium vivax following repeat controlled human malaria infection. [PDF]

open access: yesNat Commun
Hou MM   +38 more
europepmc   +1 more source

Switching Cathodic/Anodic Electrochemiluminescence of Ru(bpy)32+ Precisely via Homogeneous Nickel Nanoparticles Crystal Facets Sites Modulated ORR/OER

open access: yesExploration, EarlyView.
Mechanistic Illustration of the facet modulated Ru(bpy)32+ cathodic/anodic ECL system. O2 molecules undergo ORR at the cathode, while H2O molecules undergo OER at the anode on different catalyst facets. Ni/NG‐1 exhibits high OER but low ORR activity, generating radicals that react with Ru(bpy)32+ to enhance cathodic ECL. In contrast, Ni/NG‐2 shows high
Zixin Deng   +16 more
wiley   +1 more source

Single-round infectious rotaviruses with deletions of VP7 or VP4 genes, based on SA11 and WC3 strain backbones, and their potential use as viral vectors. [PDF]

open access: yesPLoS Pathog
Kotaki T   +12 more
europepmc   +1 more source

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