The introduction outlines the review scope. Microbial cell factories as living drugs cover host–gut microbiota, bacteria, yeast, and other microbial systems, with comparative host advantages. Engineering strategies include synthetic circuits, quorum sensing, and memory.
Cemile Elif Özçelik +3 more
wiley +1 more source
Going beyond size: exploring the metabolic burden in <i>Pseudomonas putida</i> during heterologous protein production. [PDF]
Beentjes M +4 more
europepmc +1 more source
Asymmetric Reduction of Unactivated Alkenes
Unactivated alkenes rank among the most inert functional groups in synthesis and their selective reduction remains challenging. This Review charts the evolution from classical metal‐catalyzed hydrogenation to radical hydrogen atom transfer (HAT) and emerging biocatalytic concepts, highlighting how complementary mechanistic strategies, including the ...
Nico D. Fessner +3 more
wiley +1 more source
Developing an <i>E. coli</i> heterologous expression system for characterizing a marine debrominase from <i>Roseobacter</i> sp. [PDF]
Li X +7 more
europepmc +1 more source
An L (polymerase) deficient rabies virus defective interfering particle RNA is replicated and transcribed by heterologous helper virus proteins [PDF]
Conzelmann, Karl-Klaus +2 more
core
Chemical Ligation of Backbone N‐hydroxylated Peptides
Peptide backbone N‐hydroxylation enables sequence‐agnostic fragment ligation via hydroxamate O‐acyl capture and O→N acyl transfer in water. Broad tolerance of sterically demanding nucleophilic residues is observed, and reductive N─O cleavage restores the native amide bond.
Natalia Cano‐Sampaio +1 more
wiley +1 more source
Heterologous expression of <i>Vibrio natriegens</i> transporters enhances the growth of <i>Escherichia coli</i> and <i>Bacillus subtilis</i> on glutamate. [PDF]
Han F +7 more
europepmc +1 more source
This review highlights biocatalytic prenylation as a versatile strategy for tailoring the functional properties of peptides and proteins. By comparing branched isoprenoids with linear lipids, we illustrate how specific prenyl architectures modulate the behaviors of lipidated proteins within membrane environments.
Daisuke Fujinami +2 more
wiley +1 more source
Dissecting host stress responses for predictable heterologous gene expression in E. coli. [PDF]
Rode C +8 more
europepmc +1 more source

