ABSTRACT We present the first x‐ray crystallographic structural evidence of an archaeal DNA ligase showing the AMP covalent adduct together with further cofactor hydrolysis, capturing a transient intermediary in the first step of the ligation reaction, triggered by the pyrophosphate hydrolysis.
A. X. Quintana‐Armas +3 more
wiley +1 more source
Model-guided chemical environment and metabolic network design to couple pathways with cell fitness. [PDF]
Kakko von Koch N +7 more
europepmc +1 more source
Heterologous High Level Expression, Purification, and Enzymological Properties of Recombinant Rat Cobalamin-dependent Methionine Synthase [PDF]
Kazuhiro Yamada +3 more
openalex +1 more source
This article reports the first genome sequence of a UK Alternaria brassicae isolate. Dual RNA‐sequencing profiling of A. brassicae‐infected Brassica juncea leaves identified differentially expressed genes involved in pathogenicity and host response pathways in moderately resistant Sej‐2 (2) and moderately susceptible Pusa Jaikisan cultivars.
Kevin M. King +6 more
wiley +1 more source
Optimized multi-epitope neoantigen human cytomegalovirus vaccine based on adenovirus vectors elicits potent antiviral immunity. [PDF]
Jiang S +12 more
europepmc +1 more source
PEARL: Protein Eluting Alginate with Recombinant Lactobacilli
Probiotic lactobacilli meet engineered living materials: This study introduces PEARL (protein eluting alginate with recombinant lactobacilli), an innovative engineered living material combining Lactiplantibacillus plantarum and alginate beads for controlled protein release.
Varun Sai Tadimarri +7 more
wiley +1 more source
Heterologous biosynthetic crosstalk with the native mansouramycin cluster in <i>Streptomyces albus</i> Del14 reveals unexpected metabolites. [PDF]
Stierhof M +8 more
europepmc +1 more source
Congregation for the Doctrine of the Faith: Instruction on Respect for Human Life in Its Origin and on the Dignity of Procreation: Replies to Certain Questions of the Day, Vatican City 1987 [PDF]
Bovone, Alberto, Ratzinger, Joseph
core +1 more source

