Results 61 to 70 of about 434,960 (396)

Durability of immune response against omicron BA.2 and BA.4/5 and T cell responses after boosting with mRNA and adenoviral vector-based vaccines following heterologous CoronaVac/ChAdOx-1nCov-19 vaccination

open access: yesHuman Vaccines & Immunotherapeutics, 2023
Heterologous vaccination with inactivated vaccine followed by adenoviral vector-based vaccine has shown superiority in enhancing immune response compared to homologous primary series.
Nungruthai Suntronwong   +6 more
doaj   +1 more source

Strain- and dose-dependent reduction of Toxoplasma gondii burden in pigs is associated with interferon-gamma production by CD8+ lymphocytes in a heterologous challenge model [PDF]

open access: yes, 2017
Toxoplasma gondii is a worldwide prevalent parasite of humans and animals. The global infection burden exceeds yearly one million disability-adjusted life years (DALY's) in infected individuals. Therefore, effective preventive measures should be taken to
Bert Devriendt   +6 more
core   +2 more sources

Pass-back chain extension expands multimodular assembly line biosynthesis. [PDF]

open access: yes, 2020
Modular nonribosomal peptide synthetase (NRPS) and polyketide synthase (PKS) enzymatic assembly lines are large and dynamic protein machines that generally effect a linear sequence of catalytic cycles.
Huan, Tao   +5 more
core  

The importance of booster vaccination in the context of Omicron wave

open access: yesFrontiers in Immunology, 2022
Omicron (B.1.1.529) was first detected in a sample collected in Botswana on November 11, 2021, and has rapidly replaced Delta as the dominant global variant given the robust transmissibility.
Zichun Wei   +5 more
doaj   +1 more source

Improved photosynthetic capacity and photosystem I oxidation via heterologous metabolism engineering in cyanobacteria

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2021
Significance Cyanobacteria have been increasingly explored as a biotechnological platform, although their economic feasibility relies in part on the capacity to maximize their photosynthetic, solar-to-biomass energy conversion efficiency.
María Santos-Merino   +6 more
semanticscholar   +1 more source

Heterologous saRNA Prime, DNA Dual-Antigen Boost SARS-CoV-2 Vaccination Elicits Robust Cellular Immunogenicity and Cross-Variant Neutralizing Antibodies

open access: yesFrontiers in Immunology, 2022
We assessed if immune responses are enhanced in CD-1 mice by heterologous vaccination with two different nucleic acid-based COVID-19 vaccines: a next-generation human adenovirus serotype 5 (hAd5)-vectored dual-antigen spike (S) and nucleocapsid (N ...
Adrian Rice   +17 more
doaj   +1 more source

A sigma factor toolbox for orthogonal gene expression in Escherichia coli [PDF]

open access: yes, 2018
Synthetic genetic sensors and circuits enable programmable control over timing and conditions of gene expression and, as a result, are increasingly incorporated into the control of complex and multi-gene pathways.
Bervoets, Indra   +6 more
core   +4 more sources

Homologous and heterologous desensitization of guanylyl cyclase-B signaling in GH3 somatolactotropes [PDF]

open access: yes, 2013
The guanylyl cyclases, GC-A and GC-B, are selective receptors for atrial and C-type natriuretic peptides (ANP and CNP, respectively). In the anterior pituitary, CNP and GC-B are major regulators of cGMP production in gonadotropes and yet mouse models of ...
A Faivre-Bauman   +65 more
core   +3 more sources

Adenosarcoma de alto grado de endocérvix y cavidad endometrial con componente heterólogo de rabdomiosarcoma. Reporte de caso y revisión de la literatura

open access: yesRevista Colombiana de Obstetricia y Ginecología, 2019
Objetivo: presentar el caso de una paciente con diagnóstico de adenosarcoma de alto grado de endocérvix y de cavidad endometrial, con componente heterólogo, y hacer una revisión de la literatura con especial atención al diagnóstico y manejo terape ...
Zoraida Frías-Sánchez   +5 more
doaj   +1 more source

The type of adjuvant in whole inactivated influenza a virus vaccines impacts vaccine-associated enhanced respiratory disease [PDF]

open access: yes, 2018
Influenza A virus (IAV) causes a disease burden in the swine industry in the US and is a challenge to prevent due to substantial genetic and antigenic diversity of IAV that circulate in pig populations.
Gauger, P C   +7 more
core   +1 more source

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