Results 201 to 210 of about 145,939 (263)

Engineering Streptomyces coelicolor for heterologous expression of the thiopeptide GE2270A-A cautionary tale. [PDF]

J Ind Microbiol Biotechnol
Del Carratore F, Hanko EKR, Schmidt K, Bilyk O, Ye Huang S, Iorio M, Pérez-Bonilla M, Pérez-Redondo R, Rudden M, Severi E, Tocchetti A, Sosio M, Johnson EJ, Kirkwood T, Whittall DR, Manousaki A, Genilloud O, Rodríguez-García A, Thomas GH, Donadio S, Breitling R, Takano E.   +21 more
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Heterologous Expression and Characterization of Cellouronate (β-1,4-Glucuronan) Lyase from a Human Intestinal Bacterium <i>Bacteroides luhongzhouii</i>. [PDF]

J Appl Glycosci (1999)
Tanaka Y, Matsumura K, Ariga M, Konno N, Ogata M, Habu N.   +5 more
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Heterologous Expression of Recombinant Ginseng Tetradecapeptide in <i>Saccharomyces cerevisiae</i> and Evaluation of Its Biological Activity. [PDF]

Foods
Qi Y, Ma P, Wang P, Zhu C.
europepmc   +1 more source

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Errors of heterologous protein expression

Current Opinion in Biotechnology, 1996
Missense substitutions and processivity errors in the translation of heterologous proteins are expected to occur at higher frequencies than the corresponding errors of normal translation. The resulting error-containing products may overload chaperone systems.
C, Kurland, J, Gallant
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Heterologous Expression and Purification of GPCRs

2022
G protein-coupled receptors (GPCRs) are involved in a variety of human physiological processes and are attractive targets for treating various diseases. Yet, despite the importance as therapeutic targets, only 97 unique GPCR structures have been determined to date.
Xiaoting, Li, Ling, Shen, Junlin, Liu, Xiaoyan, Liu, Zhi-Jie, Liu, Tian, Hua   +5 more
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Expression of heterologous proteins in Aspergillus

Journal of Biotechnology, 1991
Filamentous fungi, in particular those of the genus Aspergillus have been well exploited for their ability to produce high levels of extracellular proteins in an inexpensive manner. Since many human proteins with the potential to be used therapeutically are secreted and require post-translational modification for biological activity, eukaryotic ...
M, Devchand, D I, Gwynne
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Heterologous protein expression in filamentous fungi

Trends in Biotechnology, 2005
Filamentous fungi are commonly used in the fermentation industry for the large-scale production of proteins--mainly industrial enzymes. Recent advances in fungal genomics and related experimental technologies such as gene arrays and proteomics are rapidly changing the approaches to the development and use of filamentous fungi as hosts for the ...
K M Helena, Nevalainen, Valentino S J, Te'o, Peter L, Bergquist   +2 more
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Codon bias and heterologous protein expression

Trends in Biotechnology, 2004
The expression of functional proteins in heterologous hosts is a cornerstone of modern biotechnology. Unfortunately, proteins are often difficult to express outside their original context. They might contain codons that are rarely used in the desired host, come from organisms that use non-canonical code or contain expression-limiting regulatory ...
Claes, Gustafsson, Sridhar, Govindarajan, Jeremy, Minshull   +2 more
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Heterologous biopharmaceutical protein expression in Streptomyces

Trends in Biotechnology, 1997
The commercial production of human proteins in recombinant microorganisms for therapeutic use is well established. Systems have been developed to exploit the natural ability of certain bacteria to secrete properly folded, bioactive proteins into the extracellular medium.
C, Binnie, J D, Cossar, D I, Stewart
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Heterologous gene expression in Bacteroides fragilis

Plasmid, 1992
Bacteroides fragilis and other gastrointestinal tract Bacteroides are unusual gram-negative eubacteria in that genes from other gram-negative eubacteria are not expressed when introduced into these organisms. To analyze gene expression in Bacteroides, expression vector and promoter probe (detection) vector systems were developed.
C J, Smith, M B, Rogers, M L, McKee
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