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Expression of Heterologous Genes
1991With the advent of recombinant DNA technology in the mid-1970s a number of shrewd academics quickly realized the commercial potential of these tools in producing proteins of high commercial value, which, until that time, had proven both difficult and expensive to isolate in quantities sufficient for clinical trials.
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Sarcoglycan heterologous expression.
2004Mutations in sarcoglycans (SGs) cause autosomal-recessive limb-girdle muscular dystrophy. SGs exist as a complex of four transmembrane proteins (a, b, c, and d). We have recently shown that a-SG is an ecto-ATPase, i.e. an enzyme able to hydrolyze extracellular ATP.
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Heterologous Expression Systems for Lipases: A Review
2012The production of heterologous lipases is one of the most promising strategies to increase the productivity of the bioprocesses and to reduce costs, with the final objective that more industrial lipase applications could be implemented. In this chapter, an overview of the most common microbial expression systems for the overproduction of microbial ...
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