Results 131 to 140 of about 8,141 (357)

Robotic Materials With Bioinspired Microstructures for High Sensitivity and Fast Actuation

Advanced Science, EarlyView.
In the review paper, design rationale and approaches for bioinspired sensors and actuators in robotics applications are presented. These bioinspired microstructure strategies implemented in both can improve the performance in several ways. Also, recent ideas and innovations that embed robotic materials with logic and computation with it are part of the
Sakshi Sakshi, Rohit Pratyush Behera, Hongyu Zhou, Yifan Wang, Hortense Le Ferrand   +4 more
wiley   +1 more source

Mitochondrial Dysfunction in Congenital Heart Disease

Journal of Cardiovascular Development and Disease
Mitochondria play a crucial role in multiple cellular processes such as energy metabolism, generation of reactive oxygen species, excitation–contraction coupling, cell survival and death.
Julie Pires Da Silva, Mariana Casa de Vito, Carissa Miyano, Carmen C. Sucharov   +3 more
doaj   +1 more source

Characterization of Anatomical and Cardiac Abnormalities in Heterotaxy Syndrome: A Retrospective Study

Pakistan Heart Journal
Objectives: Heterotaxy Syndrome is a rare and complex congenital condition characterized by abnormal arrangement of thoraco-abdominal organs and associated congenital heart disease.
Parveen Akhtar, Kiran Hanif, Abdul Sattar, Fahad Khan, Naveed Ullah Khan, N. Jamal, Khurram Zafar, Naela Ashraf, Safwan Abdul Rahim, Najma Patel   +9 more
semanticscholar   +1 more source

Single‐Nucleus Multi‐Omics Reveals Hypoxia‐Driven Angiogenic Programs and Their Epigenetic Control in Sinonasal Squamous Cell Carcinoma

Advanced Science, EarlyView.
Single‐nucleus multi‐omics profiling of sinonasal squamous cell carcinoma unveils a hypoxia‐driven angiogenic axis. A specific hypoxic tumor subpopulation orchestrates endothelial tip cell differentiation via epigenetically regulated ADM and VEGFA secretion.
Chaelin You, Jaewoo Park, Jung Yeon Jang, Junho Noh, Jaehyun Lee, Geunho Kwon, Myeong Sang Yu, Yoo‐Sam Chung, Seung‐Jun Lee, Keunsoo Kang, Jihwan Park, Ji Heui Kim, Kyuho Kang   +12 more
wiley   +1 more source

PIERCE1 is critical for specification of left-right asymmetry in mice. [PDF]

The specification of left-right asymmetry of the visceral organs is precisely regulated. The earliest breakage of left-right symmetry occurs as the result of leftward flow generated by asymmetric beating of nodal cilia, which eventually induces ...
Baek, IJ, Gho, YS, Kim, YH, Lee, HW, Lee, YJ, Oh, SP, Sung, YH   +6 more
core   +1 more source

Allelic Variation in Maize Malate Dehydrogenase 7 Shapes Promoter Methylation and Banded Leaf and Sheath Blight Resistance

Advanced Science, EarlyView.
In this study maize chloroplastic malate dehydrogenase7 (ZmMDH7), is identified as a Rhizoctonia solani resistance gene in maize. ZmMDH7 is regulated by transcription factor ZmWRKY44 via pathogens challenge to elevate mitochondrial ROS and SA signaling pathway.
Luyang Wei, Junbin Chen, Chuang Liu, DanDan Liu, Meida Du, Shengfeng He, Wenyu Cheng, Vijai Bhadauria, You‐Liang Peng, Wangsheng Zhu   +9 more
wiley   +1 more source

High-field MR imaging in pediatric congenital heart disease: Initial results [PDF]

, 2014
BackgroundComprehensive assessment of pediatric congenital heart disease (CHD) at any field strength mandates evaluation of both vascular and dynamic cardiac anatomy for which diagnostic quality contrast-enhanced magnetic resonance angiography (CEMRA ...
Gary Satou, Ihab Ayad, J. Paul Finn, John M. Moriarty, Kim-Lien Nguyen, Kiyarash Mohajer, M. Ines Boechat, Pierangelo Renella, Sarah N. Khan, Swati Patel   +9 more
core   +1 more source

Impact of Cardiac Position, Morphology and Operative Technique on Long-Term Fontan Outcomes in Heterotaxy

medRxiv
Objectives: Heterotaxy is characterized by complex venous connections and cardiac position requiring individualized strategies for Fontan. This study aimed to assess 25-year outcomes of heterotaxy patients undergone Fontan operation, with particular ...
MD PhD Sachiko Kadowaki, Zeynep, Chun-Po, Steve Fan, P.Stat, Yasmin Zahiri BSc, Kok, MSc Hooi Yap MD, MD PhD Teerapong Tocharoenchok, MD PhD Weidan Chen, M. F. Anne I. Dipchand, MD PhD Osami Honjo, MD PhD David J. Barron   +12 more
semanticscholar   +1 more source

Targeting WEE1 in ARID1A/TP53 Concurrent Mutant Colorectal Cancer by Exploiting R‐Loop Accumulation and DNA Repair Deficiencies

Advanced Science, EarlyView.
ARID1A, a SWI/SNF complex component, is frequently mutated in colorectal cancer (CRC). CRC with ARID1A/TP53 concurrent mutations shows marked sensitivity to WEE1 inhibition. ARID1A loss induces R‐loop‐mediated replication stress, impairs ATF3 transcription, and amplifies WEE1i‐induced DNA damage, suggesting a promising therapeutic vulnerability ...
Chi Zhang, Yanjing Zhu, Luoyan Ai, Jingyuan Wang, Shan Yu, Yichen Wang, Xiaojing Xu, Mengling Liu, Yiyi Yu, Mengxuan Zhu, Yutong Liu, Zhenghang Xu, Haojie Zhou, Huishan Li, Qihong Huang, Qing Liu, Ke Peng, Tianshu Liu   +17 more
wiley   +1 more source

Multicenter Validation of the Vasoactive-Ventilation-Renal Score as a Predictor of Prolonged Mechanical Ventilation After Neonatal Cardiac Surgery [PDF]

, 2018
Objectives: We sought to validate the Vasoactive-Ventilation-Renal score, a novel disease severity index, as a predictor of outcome in a multicenter cohort of neonates who underwent cardiac surgery. Design: Retrospective chart review.
Cashen, Katherine, Costello, John M., Gowda, Keshava Murty Narayana, Grimaldi, Lisa M., Mastropietro, Christopher W., Moser, Elizabeth A. S., Piggott, Kurt D., Wilhelm, Michael   +7 more
core   +1 more source