Results 51 to 60 of about 2,766 (141)

TRANSPOSITION OF GREAT ARTERIES: NEW INSIGHTS INTO THE PATHOGENESIS

Frontiers in Pediatrics, 2013
Transposition of great arteries (TGA) is one of the most common and severe congenital heart diseases (CHD). It is also one of the most mysterious CHD because it has no precedent in phylogenetic and ontogenetic development, it does not represent an ...
Marta eUnolt, Carolina ePutotto, Lucia Martina Silvestri, Dario eMarino, Alessia eScarabotti, Valerio eMassaccesi, Angela eCaiaro, Paolo eVersacci, Bruno eMarino, Bruno eMarino   +9 more
doaj   +1 more source

A novel DNAH11 variant segregating in a sibship with heterotaxy and implications for genetic counseling

Molecular Genetics & Genomic Medicine, 2020
Background Isomerism or heterotaxy syndrome is the loss of normal asymmetry of the internal thoraco‐abdominal organs in the left‐right axis and is associated with cardiovascular malformations.
Amirpouyan Namavarian, Anas Eid, Elaine Suk‐Ying Goh, Varsha Thakur   +3 more
doaj   +1 more source

Malposition of a Port Catheter in the Azygos Vein: Endovascular Repositioning Using a Long Loop Snare Technique

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Port catheters provide a reliable, long‐term venous access option in children for repeated administration of medications or parenteral nutrition. A cardiac catheterization procedure was performed in a 7‐year‐old girl in whom lateral chest radiography revealed posterior deviation suggestive of azygos vein malposition.
Axel Rentzsch, Annabelle Wagner, Jochen Pfeifer, Hashim Abdul‐Khaliq   +3 more
wiley   +1 more source

Malrotation and volvulus associated with heterotaxy syndrome

Journal of Indian Association of Pediatric Surgeons, 2012
A 2-year-old boy with heterotaxy syndrome with associated polysplenia, ventricular septal defect, and malrotation of gut with volvulus is presented. There was delay in diagnosis due to the unusual plain abdominal radiography findings.
Santosh K Mahalik, Sanat Khanna, Prema Menon   +2 more
doaj   +1 more source

A Systematic Review on Disease‐Modifying Therapies in Parkinsonian Disorders

Clinical Pharmacology &Therapeutics, EarlyView.
Parkinsonian disorders, including Parkinson's disease, Lewy body dementia, multiple system atrophy, and progressive supranuclear palsy, are progressive neurodegenerative conditions with no treatment options to slow disease progression. This systematic review provides an overview of evidence of disease‐modifying therapies that have been evaluated in ...
Pepijn P.N.M. Eijsvogel, Lars M.G. Smits, Philip H.C. Kremer, Geert Jan Groeneveld   +3 more
wiley   +1 more source

A breviloquent description about the challenges involved and the management strategies for the complex cardiac abnormality — Ivemark syndrome

Journal of Rare Diseases
Ivemark syndrome, a classification of heterotaxy syndrome, is an extremely uncommon congenital condition. An aberrant configuration of the thoracoabdominal organs across the body’s left–right axis is known as heterotaxy, and it is always linked to either
Pooja C., Sankari A., Sashtipriyaa R., Mariyam Susan Joji, Sarumathy S.   +4 more
doaj   +1 more source

Secretopathies emerge as a new class of neurocristopathies

Developmental Dynamics, EarlyView.
Abstract Neural crest cells are a transient embryonic population of cells that give rise to a wide range of structures, including craniofacial cartilage and bone, peripheral neurons and glia, as well as components of the cardiac outflow tract, among others.
Amanda Teixeira, Cassandra Millet‐Boureima, Joshua A. Moore, Loydie A. Jerome‐Majewska   +3 more
wiley   +1 more source

The effects of sodium–glucose cotransporter 2 inhibitors on the ‘forgotten’ right ventricle

ESC Heart Failure, Volume 12, Issue 2, Page 1045-1058, April 2025.
Abstract With the progress in diagnosis, treatment and imaging techniques, there is a growing recognition that impaired right ventricular (RV) function profoundly affects the prognosis of patients with heart failure (HF), irrespective of their left ventricular ejection fraction (LVEF).
Liangzhen Qu, Xueting Duan, Han Chen
wiley   +1 more source

Transcriptomic signatures reveal systemic adaptations and immune modulation in response to training and competitive racing in horses

Equine Veterinary Journal, EarlyView.
Abstract Background The molecular mechanisms underlying adaptation to physical exertion and racing stress in horses remain incompletely understood. Peripheral blood transcriptomics offers a minimally invasive method to monitor systemic responses to exercise and identify biomarkers of adaptation or overload. Objectives To evaluate transcriptomic changes
Izabela Dąbrowska, Jowita Grzędzicka‐Agko, Paula Kiełbik, Michał Trela, Olga Witkowska‐Piłaszewicz   +4 more
wiley   +1 more source

A Han-Chinese Fetus With Heterotaxy Syndrome Caused by Novel Compound Heterozygous Mutations in PKD1L1: A Case Report

Clinical and Experimental Obstetrics & Gynecology
Background: Heterotaxy syndrome is characterized by abnormal organ arrangement across the left-right (L-R) axis, often leading to complex congenital heart defects (CHDs).
Xinyuan Teng, Jiayao Zhao, Jiayu Shen, Jin Yao, Liangfang Tang, Jingwei Xu, Yi Chen, Liquan Wang   +7 more
doaj   +1 more source