Results 221 to 230 of about 81,851 (305)

Prosocial helping behaviors attenuate accelerated cognitive decline driven by APOE ε4

Alzheimer's &Dementia, Volume 22, Issue 9, September 2026.
Abstract INTRODUCTION The apolipoprotein E (APOE) ε4 allele accelerates cognitive decline through multiple biological pathways—including neuroinflammatory, vascular, and stress‐regulatory mechanisms—yet few modifiable behaviors counter this genetic vulnerability.
Sae Hwang Han, Jessica Danielle Faul
wiley   +1 more source

Pleistocene Legacies in the Contemporary Population Genetic Structure of an Acid-Specialised Crayfish, the Threatened Sand Yabby <i>Cherax robustus</i>. [PDF]

Ecol Evol
Smith G, Ventura T, Yule CM.
europepmc   +1 more source

Seascape Genomics Uncovers Weak Signs of Local Adaptation Despite Bottleneck Events, High Inbreeding and Low Heterozygosity in the Vulnerable Smooth Hammerhead Shark (Sphyrna zygaena)

Aquatic Conservation: Marine and Freshwater Ecosystems, Volume 36, Issue 9, September 2026.
ABSTRACT The smooth hammerhead shark (Sphyrna zygaena) is a highly migratory pelagic predator classified as Vulnerable due to overexploitation and rapid climate change. However, its genomic diversity, connectivity patterns and demographic history remain poorly understood.
Bruno Lopes da Silva Ferrette, Rui Coelho, Rodrigo Rodrigues Domingues, Diego Peres Alonso, Paulo Eduardo Martins Ribolla, Claudio Oliveira, Fernando Fernandes Mendonça   +6 more
wiley   +1 more source

Lecanemab and amyloid-related imaging abnormalities: Real-world data from a single center experience. [PDF]

Alzheimers Dement (Amst)
Wallace A, Zhou O, Hoang MN, Porter G, Padilla C, Marshall C.   +5 more
europepmc   +1 more source

Tissue Damage in Rheumatoid Arthritis Is Genetically Linked to Low Peptidylglycine Alpha‐Amidating Monooxygenase Activity in Synovial Fibroblasts

Arthritis &Rheumatology, Volume 78, Issue 9, Page 1837-1849, September 2026.
Objective Both susceptibility to, and severity of, rheumatoid arthritis (RA) is associated with the rs26232 C allele. Our primary aim was to identify the biologic mechanism underlying this association. Methods Expression of surrounding genes was compared among rs26232 genotypes.
Kevin J. Sheridan, Emma R. Dorris, Maria Inês Pimenta, Jemma Falkov, Matthew Fisher, Sam Pledger, Hector Devey, Munitta Muthana, Denis C. Shields, Richard E. Mains, Betty A. Eipper, Christopher D. Buckley, Anthony G. Wilson   +12 more
wiley   +1 more source

APOE ε4-associated hippocampal atrophy trajectories across the Alzheimer's disease continuum: a systematic review, meta-analysis, and longitudinal validation. [PDF]

Front Aging Neurosci
Cai M, Lei H, Zhang Y, Zou J, Cao W, Wang Y, Wei K.   +6 more
europepmc   +1 more source

UGT1A1 genotype testing for irinotecan: A guideline developed by the UK Centre of Excellence in Regulatory Science and Innovation in Pharmacogenomics (CERSI‐PGx)

British Journal of Clinical Pharmacology, Volume 92, Issue 9, Page 2986-3001, September 2026.
Abstract Irinotecan, a topoisomerase I inhibitor, is available as both non‐pegylated and pegylated formulations. The non‐pegylated formulation is licensed for use in advanced colorectal cancer either in combination with other agents or as monotherapy.
Dharmisha Chauhan, Cinzia Dello Russo, Jack Thompson, Dyfrig A. Hughes, Katherine Payne, Maria Tsakiroglou, Paul Ross, Rena Chauhan, Simon Jenkinson, Jessica Keen, Sophie Harding, Eleanor Lau, Michael Braun, Roshan Agarwal, Richard Adams, Elisabeth Rolf, Farah Al‐Sheikhli, Sarah Mitchell, Ruth Hammond, Rosie Roberts, Lorna Cairns, Shirley Heggarty, Janet Graham, Justin Mencel, Munir Pirmohamed   +24 more
wiley   +1 more source

Semi-connected structure and asymmetric gene flow of <i>Nypa fruticans</i> Wurmb. across the Philippine archipelago. [PDF]

Front Plant Sci
Suhardi RM, Mantiquilla JA, Palangasinghe PC, Shih HC, Muthusamy A, Shiao MS, Chiang YC.   +6 more
europepmc   +1 more source

The Small but Versatile Cyclin‐Dependent Kinase Subunit CKS

BioEssays, Volume 48, Issue 9, September 2026.
The cyclin‐dependent kinase subunit, CKS, is required for anaphase onset during both meiosis I and II in Caenorhabditis elegans oocytes. One model for how CKS promotes meiosis II anaphase onset involves phosphorylation of a Cullin 2 E3 ligase by CDK/CKS/CYB‐3, followed by the CKS anion pocket binding to the phosphorylated E3, recruiting CDK/CKS/CYB‐1 ...
Jie Yang, Bruce Bowerman
wiley   +1 more source

Genetic Analysis of a Family With Hereditary Factor V Deficiency Induced by Compound Heterozygous Variants (IVS24+3A>T and p.Asp2222Gly). [PDF]

Haemophilia
Huang B, Zhang Y, Zhang L, Wang L, Su K.
europepmc   +1 more source