Results 91 to 100 of about 299,280 (207)

Lp(a) levels in Greek patients with heterozygous familial hypercholesterolemia

, 1996
We undertook the present study to evaluate the lipid profile in 82 (51 male, 31 female) Greek individuals with heterozygous familial hypercholesterolemia (FH), aged 13-61 years from 22 families.
Elisaf, M. S., Siamopoulos, K. C., Bairaktari, H.   +2 more
core  

Aortic stiffness in young patients with heterozygous familial hypercholesterolemia

American Heart Journal, 1998
Dyslipidemia is a primary risk factor for the development of atherosclerosis. Aortic distensibility is an important determinant of left ventricular function and coronary blood flow whose possible alterations in patients with dyslipidemia have not been fully investigated.To assess the effect of dyslipidemia on the elastic properties of the aorta, we ...
Pitsavos, C, Toutouzas, K, Dernellis, J, Skoumas, J, Skoumbourdis, E, Stefanadis, C, Toutouzas, P   +6 more
openaire   +3 more sources

Familial heterozygous hypercholesterolemia: a clinical case

, 2016
Резюме. У статті наведено клінічний випадок сімейної гетерозиготної гіперхолестеринемії з розвитком у пацієнтки гострого інфаркту міокарда з подальшим проведенням аортокоронарного шунтування.
М'якінькова, Людмила Олександрівна, Катеренчук, Іван Петрович, Вакуленко, Костянтин Євгенійович, Katerenchuk, I. P., Shabliy, L. M., Vakulenko, K. Ye., Шаблій, Людмила Миколаївна, Miakinkova, L. O.   +7 more
core  

A 4-year trial of simvastatin in the treatment of patients with heterozygous familial hypercholesterolemia [PDF]

A study was conducted to determine the clinical efficacy and tolerability of simvastatin, an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase in seven patients with heterozygous familial hypercholesterolemia (FH) (defined as primary ...
00019960, 70167, 稲津, 明広, 小泉, 順二, Inazu, Akihiro, 70168, Kajinami, Kouji, Mabuchi, Hiroshi, Koizumi, Junji, 80293348, 梶波, 康二, 68650, 馬渕, 宏, Kitatani, Masako, 73409, 73408, 20161846   +16 more
core   +1 more source

Familial hypercholesterolemia [PDF]

, 2006
Familial hypercholesterolemia is a hereditary disease characterized with the increase of LDL- cholesterol level in plasma as a result of mutational defect of LDL receptor gene. The disease presents in two forms as homozygous and heterozygous.
Güzelmansur, İsmail, İncecik, Faruk, Akçalı, Cenk, Sangün, Özlem   +3 more
core  

Assessing the Impact of Inclisiran on LDL-C and PCSK9 Reduction in Hypercholesterolemic Patients: A Meta-analysis of Cardiovascular Metabolic Prevention

International Journal of the Cardiovascular Academy
Hypercholesterolemia, a major contributor to atherosclerotic cardiovascular disease, remains inadequately controlled despite widespread statin use, particularly in patients with familial hypercholesterolemia or statin intolerance.
Agung Cendekia Putra Nusantara, Ariella Diandihati Rapsanjani, Ikhwan Handirosiyanto, Tara Mandiricha, Aisyah Silvia Gaffar   +4 more
doaj   +1 more source

Efficacy and safety of alirocumab in patients with hypercholesterolemia not adequately controlled with non-statin lipid-lowering therapy or the lowest strength of statin: ODYSSEY NIPPON study design and rationale

Lipids in Health and Disease, 2017
Background Statins are generally well-tolerated and serious side effects are infrequent, but some patients experience adverse events and reduce their statin dose or discontinue treatment altogether. Alirocumab is a highly specific, fully human monoclonal
Tamio Teramoto, Akira Kondo, Arihiro Kiyosue, Mariko Harada-Shiba, Yasushi Ishigaki, Kimimasa Tobita, Yumiko Kawabata, Asuka Ozaki, Marie T. Baccara-Dinet, Masataka Sata   +9 more
doaj   +1 more source

Portuguese Familial Hypercholesterolemia Study: presentation of the study and preliminary results [PDF]

, 2006
Familial hypercholesterolemia (FH) is an autosomal dominant genetic disorder caused, in the majority of cases, by a partial or total lack of functional low density lipoprotein receptors (LDLR).
Rato, Q., Bourbon, M., Investigadores do Estudo Português de Hipercolesterolemia Familiar   +2 more
core   +1 more source

Characteristic cardiovascular manifestation in homozygous and heterozygous familial hypercholesterolemia [PDF]

, 1999
Background The aortic valve dysfunction of patients with homozygous familial hypercholesterolemia (FH) suggests that hypercholesterolemia affects not only coronary arteries, but also the aortic valve.
Yutani, Chikao, Miyatake, Kunio, Tsushima, Motoo, Yamamura, Taku, Beppu, Shintarou, Yamamoto, Akira, Kawaguchi, Akito, Shintarou Beppu, Taku Yamamura, Motoo Tsushima, Akira Yamamoto, Kunio Miyatake, Akito Kawaguchi, Chikao Yutani   +13 more
core   +1 more source

CASCADE GENETIC SCREENING IN DIAGNOSTICS OF HETEROZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA: CLINICAL CASE

Российский кардиологический журнал, 2017
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E. V. Shakhtshneider, D. E. Ivanoshchuk, K. V. Makarenkova, P. S. Orlov, O. V. Timoshchenko, S. S. Bazhan, Yu. P. Nikitin, M. I. Voevoda   +7 more
doaj   +1 more source