Results 111 to 120 of about 299,280 (207)

Heterozygous familial hypercholesterolemia: the first challenge for anti-PCSK9 monoclonal antibodies

, 2016
Heterozygous familial hypercholesterolemia (HeFH) is characterized by a prevalence of 1/200 (higher than 1/500 as previously estimated): based on this updated prevalence, in Italy there are about 250-300 000 subjects with HeFH.
ZAMBON, ALBERTO
core   +1 more source

Uncovering a Windsock Aneurysm of the Interventricular Septum: An Incidental Structural Abnormality

Methodist DeBakey Cardiovascular Journal
We present a case of a 75-year-old female with a history of idiopathic small fiber neuropathy, essential hypertension, and heterozygous familial hypercholesterolemia who was evaluated for exertional dyspnea and fatigue.
Saliha Erdem, Kazim Baser
doaj   +1 more source

Aorta of young and middle-aged heterozygous familial hypercholesterolemia patients shows no functional or morphological impairment assessed by MRI

, 2008
Sami Soljanlahti1, Taina Autti1, Alpo F Vuorio2, Pekka Keto1, Hannu Turtola3, Kirsi Lauerma11Helsinki Medical Imaging Center, Helsinki University Central Hospital, Helsinki, Finland; 2Division of Internal Medicine, Department of Medicine, University of ...
Alpo F Vuorio, Pekka Keto, Sami Soljanlahti, Hannu Turtola, Taina Autti, Kirsi Lauerma   +5 more
core  

Another Use for Polygenic Risk Scores: Improving Risk Prediction for Heterozygous Familial Hypercholesterolemia. [PDF]

JACC Adv, 2023
Palmisano BT, Knowles JW.
europepmc   +1 more source

Familial Hypercholesterolemia in Pediatric Patients

, 2020
Familial hypercholesterolemia is one of the most common severe genetic conditions in the pediatric population. When left untreated, familial hypercholesterolemia could lead to cardiovascular events and, in some cases, death. This article will explore the
Ichull, Joseph A, Jr
core   +1 more source

Coronary Artery and Carotid Artery Plaques in Patients With Heterozygous Familial Hypercholesterolemia. [PDF]

JACC Adv, 2023
Tada H, Nohara A, Usui S, Sakata K, Hayashi K, Fujino N, Kawashiri MA, Takamura M.   +7 more
europepmc   +1 more source

Evaluation of Genome in Early Familial Coronary Artery Disease: A Case Report

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2019
Background and Objectives: Coronary artery diseases (CAD) are the most common cause of death in Iran and worldwide. Myocardial infarction (MI) is a complex multifactorial and the most severe type of CAD.
Mohammad Javad Ghorbani, Nematollah Razmi, Seyed Mohammad Bagher Tabei, Mohammad Javad Zibaeenezhad, Hamid Reza Goodarzi   +4 more
doaj  

Polygenic Background Modifies Risk of Coronary Artery Disease Among Individuals With Heterozygous Familial Hypercholesterolemia. [PDF]

JACC Adv, 2023
Reeskamp LF, Shim I, Dron JS, Ibrahim S, Tromp TR, Fahed AC, Patel AP, Hutten BA, Stroes ESG, Hovingh GK, Khera AV.   +10 more
europepmc   +1 more source

Plasma lipoprotein(a) levels and LDL-cholesterol lowering response to statin therapy in patients with heterozygous familial hypercholesterolemia

, 2006
Familial hypercholesterolemia (FH) is characterised by elevated plasma LDL-cholesterol levels and premature ischemic heart disease. Statin therapy is mandatory in order to prevent atherosclerosis in patients with heterozygous FH.
Cariolou, M., Elisaf, M. S., Saougos, V., Miltiadous, G.   +3 more
core  

Effect of causative genetic variants on atherosclerotic cardiovascular disease in heterozygous familial hypercholesterolemia patients. [PDF]

Front Cardiovasc Med, 2023
Matta A, Rabès JP, Taraszkiewicz D, Carrié D, Roncalli J, Ferrières J.   +5 more
europepmc   +1 more source