Results 121 to 130 of about 284,051 (203)

Characterization of Polyvascular Disease in Heterozygous Familial Hypercholesterolemia: Its Association With Circulating Lipoprotein(a) Levels. [PDF]

J Am Heart Assoc, 2022
Funabashi S, Kataoka Y, Hori M, Ogura M, Doi T, Noguchi T, Harada-Shiba M.   +6 more
europepmc   +1 more source

Statins for children with familial hypercholesterolemia

, 2017
Background: Familial hypercholesterolemia is one of the most common inherited metabolic diseases and is an autosomal dominant disorder meaning heterozygotes, or carriers, are affected. Those who are homozygous have severe disease.
Vuorio, A., Humphries, S.E., Kovanen, P.T., Drogari, E., Tonstad, S., Wiegman, A., Kuoppala, J., Ramaswami, U.   +7 more
core   +1 more source

PCSK9 Inhibitors Reduce Oxidative Stress Biomarkers in Heterozygous Familial Hypercholesterolemia. [PDF]

J Cell Mol Med
Woźniak-Szczepocka A, Pawlos A, Gorzelak-Pabiś P, Broncel M, Bukowska B, Woźniak E.   +5 more
europepmc   +1 more source

CO18 | Relationship between gut permeability and PCSK9 in heterozygous familial hypercholesterolemia

Bleeding, Thrombosis and Vascular Biology
Background: Gut dysbiosis is a major determinant of low-grade endotoxaemia via dysfunction of the intestinal barrier scaffold, which is a prerequisite for Lipopolysaccharide (LPS) translocation into the systemic circulation.
doaj   +1 more source

Non-Responder to Inclisiran and Evolocumab-A Female Patient with Heterozygous Familial Hypercholesterolemia and Statin Intolerance. [PDF]

Diseases
Muszyński P, Chlabicz M, Kruszyńska J, Wilk-Śledziewska K, Kazberuk P, Musiałowska D, Groth M, Dudzińska K.   +7 more
europepmc   +1 more source

Consequences of Late Diagnosis and Insufficient Cholesterol Treatment in Women With Heterozygous Familial Hypercholesterolemia. [PDF]

JACC Case Rep
Santos RD.
europepmc   +1 more source

Estimated Yield of Screening for Heterozygous Familial Hypercholesterolemia With and Without Genetic Testing in US Adults. [PDF]

J Am Heart Assoc, 2022
Bellows BK, Khera AV, Zhang Y, Ruiz-Negrón N, Stoddard HM, Wong JB, Kazi DS, de Ferranti SD, Moran AE.   +8 more
europepmc   +1 more source

Case Report: Compound heterozygous familial hypercholesterolemia in a pediatric patient with multiple cutaneous xanthomas. [PDF]

Front Pediatr
Yang Q, Jiang L, Wei X, Lv X, Zhao Y, Liu G.   +5 more
europepmc   +1 more source

Comparison of Clinical Characterization and Therapeutic Strategies between Homozygous Familial Hypercholesterolemia and Heterozygous Familial Hypercholesterolemia. [PDF]

J Atheroscler Thromb
Shishikura D, Harada-Shiba M, Michikura M, Sakaguchi K, Kusumoto H, Fujioka S, Fujisaka T, Kanzaki Y, Morita H.   +8 more
europepmc   +1 more source

Triple Assessments of Atherosclerosis in Patients With Heterozygous Familial Hypercholesterolemia. [PDF]

JACC Asia
Tada H, Kojima N, Yamagami K, Nomura A, Nohara A, Usui S, Sakata K, Kawashiri MA, Takamura M.   +8 more
europepmc   +1 more source