Hexachlorophene as a topically applied chemical for prophylaxis against Schistosoma mansoni infections in mice [PDF]
Revista do Instituto de Medicina Tropical de São Paulo, 1985 Treatment of mouse tail skins with hexachlorophene (1.25% w/v) in absolute methanol or 70% isopropanol suppressed Schistosoma mansoni infections by more than 95% even when the application was performed up to three days prior to exposure to cercarial ...
Marie M. Grenan +5 more
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Predictive Studies Suggest that the Risk for the Selection of Antibiotic Resistance by Biocides Is Likely Low in Stenotrophomonas maltophilia. [PDF]
PLoS ONE, 2015 Biocides are used without restriction for several purposes. As a consequence, large amounts of biocides are released without any control in the environment, a situation that can challenge the microbial population dynamics, including selection of ...
María Blanca Sánchez +5 more
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Determination of hexachlorophene residue in fruits and vegetables by ultra-high performance liquid chromatography-tandem mass spectrometry. [PDF]
PLoS ONEA modified QuEChERS (Quick, Easy, Cheap, Effective, Rugged and Safe) -LC-MS/MS method was developed for the determination of hexachlorophene in fruits and vegetables.
Yuan Ma +8 more
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Ivermectin Identified Using a High-Throughput Screening System Exhibits Anti-Clonorchis sinensis Activity in Rats [PDF]
AntibioticsBackground: Clonorchiasis, caused by the parasite Clonorchis sinensis, remains a public health concern in East Asian countries. Methods: In this study, high-throughput screening was used to analyze 320 compounds for potential inhibitory activity against ...
Soon-Ok Lee +7 more
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Hexachlorophene is a potent KCNQ1/KCNE1 potassium channel activator which rescues LQTs mutants. [PDF]
PLoS ONE, 2012 The voltage-gated KCNQ1 potassium channel is expressed in cardiac tissues, and coassembly of KCNQ1 with an auxiliary KCNE1 subunit mediates a slowly activating current that accelerates the repolarization of action potential in cardiomyocytes.
Yueming Zheng +6 more
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Screening of an FDA-Approved Drug Library with a Two-Tier System Identifies an Entry Inhibitor of Severe Fever with Thrombocytopenia Syndrome Virus [PDF]
Viruses, 2019 Severe fever with thrombocytopenia syndrome virus (SFTSV) is an emerging tick-borne bunyavirus that causes severe disease in humans with case-fatality rates of up to 30%. There are currently very limited treatment options for SFTSV infection.
Shuofeng Yuan +15 more
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Applied Sciences, 2022 Staphylococcus aureus is a common contaminant in artisanal raw-milk cheeses. Tolerance of S. aureus to biocides is a threat to disinfection in the cheese production environment, while antibiotic resistance and enterotoxin production are additional health
Josisleine Recalde Allaion +4 more
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VIEW Journal of European Television History and Culture, 2020 The Morhange talc affair was mediatised by television from 1972. The health scandal brought to light issues of consumerism and cosmetic products in France, after baby talcum powder was accidentally contaminated with hexachlorophene. This article presents
Coulomb, Benjamin
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Journal of Global Antimicrobial Resistance, 2020 Objectives: The incidence of severe filamentous fungal infections has increased over the past decade. Some of these filamentous fungi are resistant to available antifungals; it is thus urgent to find new compounds that are active against such life ...
Hanane Yousfi +4 more
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"INHIBITION ASSAY STUDY OF PURIFIED GLUTATHIONE S-TRANSFERASE FROM FASCIOLA HEPATICA AND SHEEP LIVER TISSUE BY HEXACHLOROPHENE" [PDF]
Acta Medica Iranica, 2004 Glutathione S-transferases (GSTs) are widespread in Fasciola. hepatica parasite and sheep liver tissue. Study of GSTs inhibition assays in F. hepatica and sheep liver tissue are a priority of chemotherapeutic targets in parasitic liver diseases including
A. Farahnak PM. Brophy
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