"Comparative Glutathione S-Transferases (GSTs) Inhibition Assay in the Whole Extract of Fasciola hepatica and Sheep Liver Tissue by Hexachlorophene" [PDF]
Recent research highlights the importance of GSTs in the establishment of chronic helminth infections. GSTs have the potential to protect the parasite against the host immune response.
A Farahnak +1 more
doaj +1 more source
Exploring Metabolic Disruption and Redox Modulation by Senna Leaf Extracts Induces Mortality in the Zoonotic Parasite <i>Hymenolepis diminuta</i>. [PDF]
Senna leaf extracts exhibit strong anthelmintic effects against the zoonotic cestode Hymenolepis diminuta, inducing profound morphological and biochemical alteration. This study investigated the underlying mechanisms, focusing on glycolytic disruption and reactive nitrogen species (RNS) generation. Live H.
Roy S, Lyndem LM.
europepmc +2 more sources
Randomized, Double-Blind, Placebo-Controlled Study on Decolonization Procedures for Methicillin-Resistant Staphylococcus aureus (MRSA) among HIV-Infected Adults. [PDF]
HIV-infected persons have increased risk of MRSA colonization and skin and soft-tissue infections (SSTI). However, no large clinical trial has examined the utility of decolonization procedures in reducing MRSA colonization or infection among community ...
Amy Weintrob +10 more
doaj +1 more source
Introduction: We previously reported that transplantation of hepatic cell sheets from human bone marrow-derived mesenchymal stem cells (BM-MSCs) with hexachlorophene, a Wnt/β-catenin signaling inhibitor, ameliorated acute liver injury.
Noriko Itaba +8 more
doaj +1 more source
Role of hydrogen bonding in conformational energies of hexachlorophene and its derivatives - A theoretical study [PDF]
Conformational space around two dihedral angles (viz., θ and φ) in hexachlorophene (HCP), dimethylhexachlorophene (DMHCP) and diphenylhexachlorophene (DPHCP), has been scanned at the AM1 level and further the minima optimized at DFT(B3LYP)/6-31G(d) level.
Padmanabhan, Kalpana ; Sri Sarada College for Women Salem-16 +2 more
core +3 more sources
Aβ accumulation plays a central role in the pathogenesis of Alzheimer's disease (AD). Recent studies suggest that the process of Aβ nucleated polymerization is essential for Aβ fibril formation, pathology spreading and toxicity. Therefore, targeting this
Simona Eleuteri +10 more
doaj +1 more source
Antiviral Drugs Against Severe Fever With Thrombocytopenia Syndrome Virus Infection
Severe fever with thrombocytopenia syndrome (SFTS) is an emerging tick-borne infectious disease caused by SFTS virus (SFTSV), which is a novel bunyavirus.
Mutsuyo Takayama-Ito, Masayuki Saijo
doaj +1 more source
Recurring Methicillin-resistant Staphylococcus aureus Infections in a Football Team
An outbreak of community-associated methicillin-resistant Staphylococcus aureus (MRSA) skin and soft tissue infection (SSTI) occurred in a college football team from August to September 2003.
Dao M. Nguyen +2 more
doaj +1 more source
Randomized Trial Of A Hexachlorophene Preparation And P-300 Bacteriostatic Soaps [PDF]
Twenty-six patients undergoing chemotherapy for acute leukemia on a protected environment-prophylactic antibiotic program were randomly assigned to bathe with either P-300 or a 3% hexachlorophene preparation.
Ebersole, Rhoda +2 more
core +1 more source
Hexachlorophene Toxicosis in a Litter of Doberman Pinschers
A litter of 5-week-old Doberman Pinschers with pustular dermatitis was treated dermally with a hexachlorophene-containing emulsion. Shortly after a second treatment, all of the puppies developed neurologic signs consisting of muscle tremors, ataxia, and
Robert H. Poppenga +5 more
core +1 more source

