Results 51 to 60 of about 1,606 (180)

Repurpose an FDA‐Approved Antibody Using DARPin‐Scaffolded Bridge Protein

Chemistry–Methods, Volume 6, Issue 5, May 2026.
The cell line and scalable upstream/downstream process development needed for every new monoclonal antibody are both highly expensive and time‐consuming, significantly increasing the cost of new antibody therapeutics. By contrast, the production of many synthetic binders can be accomplished rapidly and with lower production costs.
Michael Woolley, Joshua D. Bryant, Samuel Vrana, Karuppiah Chockalingam, Zhilei Chen   +4 more
wiley   +1 more source

Country based distribution HAdV-3 hexon variants.

, 2018
Country based distribution HAdV-3 hexon variants.
Tahmina Monwar (5029466), Leela Anthony (5029460), Ezazul Haque (5029463), Arun Kumar Adhikary (5029472), Urmila Banik (5029469)   +4 more
core   +1 more source

Integrating oncolytic adenoviruses into combination cancer therapy: Mechanisms, advances and clinical outlook

Clinical and Translational Medicine, Volume 16, Issue 5, May 2026.
Oncolytic adenoviruses synergise with chemotherapy, radiotherapy and immunotherapy to enhance anti‐tumour efficacy. Chemotherapy and radiotherapy increase tumour susceptibility and antigen release through DNA damage, while immunotherapy restores T‐cell activity.
Vlad Iova, Gilda Mihaela Iova, Mihail Silviu Tudosie, Ioana Scrobota, Catalin Gabriel Smarandache   +4 more
wiley   +1 more source

Diagnosis Confirmation of Inclusion Bodies Hepatitis on Broiler Chicken using Polymerase Chain Reaction Method

Jurnal Medik Veteriner, 2022
This study aimed to diagnose cases of Inclusion Bodies Hepatitis (IBH) in broiler chickens. A total of 6 chickens were collected from farms in Banten and Jember.
Jola Rahmahani, Maha Kirana, Fedik Abdul Rantam, Suwarno Suwarno   +3 more
doaj   +1 more source

HAdV-3 genome and hexon gene hypervariable regions.

, 2018
The HAdV-3 GB strain genome is 35345 bp long (GenBank ID: AY599834). The hexon protein is a 945–amino acid (AA) polypeptide encoded by 2835 nucleotides that extends from 18,420 to 21,254 bp in the HAdV-3 genome.
Tahmina Monwar (5029466), Leela Anthony (5029460), Ezazul Haque (5029463), Arun Kumar Adhikary (5029472), Urmila Banik (5029469)   +4 more
core   +1 more source

Systems approach to design multi-epitopic peptide vaccine candidate against fowl adenovirus structural proteins for Gallus gallus domesticus

Frontiers in Cellular and Infection Microbiology
IntroductionFowl adenovirus (FAdV) is a significant pathogen in poultry, causing various diseases such as hepatitis-hydropericardium, inclusion body hepatitis, and gizzard erosion.
Susithra Priyadarhni Mugunthan, Divyadharshini Venkatesan, Chandramohan Govindasamy, Dhivya Selvaraj, Mani Chandra Harish   +4 more
doaj   +1 more source

Insights into Adenovirus Uncoating from Interactions with Integrins and Mediators of Host Immunity

Viruses, 2016
Human adenoviruses are large (150 MDa) nonenveloped double-stranded DNA (dsDNA) viruses that cause acute respiratory, gastrointestinal and ocular infections.
Glen R. Nemerow, Phoebe L. Stewart
doaj   +1 more source

Molecular characterization of aviadenovirus serotypes and pathogenicity of the identified adenovirus in broiler chickens

Poultry Science, 2022
: Inclusion body hepatitis (IBH) is an economically significant viral disease that primarily affects broiler chickens. At least 12 different aviadenovirus serotypes are responsible for causing IBH.
Mohamed Lebdah, Dalal S. Alshaya, Areej S. Jalal, Mohamed R. Mousa, Mohamed M. Radwan, Mahmoud Samir, Amany Adel, Najah M. Albaqami, Mohamed T. El-Saadony, Khaled A. El-Tarabily, Yara F.H. El basrey   +10 more
doaj   +1 more source

Oncolytic Therapy: Delivery System and New Therapeutic Strategies for Cancer

MedComm, Volume 7, Issue 4, April 2026.
This review summarizes recent advances in nanoparticle‐ and cell‐mediated OVs delivery strategies that improve biodistribution and tumor targeting while limiting immune clearance. It also examines combination approaches that enhance therapeutic efficacy through tumor microenvironment modulation or immune activation, thereby overcoming immunosuppression
Sikan Jin, Yi Zhang, Ziling Zhou, Yaqi Zhang, Ting Yu, Rui Xu, Lin Xu, Jidong Zhang, Longze Zhang, Shan Yang, Xianyao Wang   +10 more
wiley   +1 more source

Evidence of molecular evolution driven by recombination events influencing tropism in a novel human adenovirus that causes epidemic keratoconjunctivitis. [PDF]

PLoS ONE, 2009
In 2005, a human adenovirus strain (formerly known as HAdV-D22/H8 but renamed here HAdV-D53) was isolated from an outbreak of epidemic keratoconjunctititis (EKC), a disease that is usually caused by HAdV-D8, -D19, or -D37, not HAdV-D22.
Michael P Walsh, Ashish Chintakuntlawar, Christopher M Robinson, Ijad Madisch, Balázs Harrach, Nolan R Hudson, David Schnurr, Albert Heim, James Chodosh, Donald Seto, Morris S Jones   +10 more
doaj   +1 more source