Results 41 to 50 of about 810 (162)

Control of poorly immunogenic tumors with systemic STING agonist‐loaded liposomes targeting cross‐presenting dendritic cells

Clinical &Translational Immunology, Volume 15, Issue 6, 2026.
WH‐peptide‐functionalised liposomes encapsulating STING or RIG‐I agonists target intra‐tumoral Clec9A+ cDC1 and pDC, triggering release of type 1 IFN, presentation of CD4 and CD8 endogenous tumor epitopes, expansion of CTL with help from CD4 T cells in spleen, and tumor cell killing.
Bijun Zeng, Meghna Talekar, Thais Aragao‐Horoiwa, Amy Cameron, Guangzu Zhao, Yulia Zybina, Wendy Blumenschein, Karyn van de Mark, Wittaya Suwakulsiri, Gretchen A Baltus, Riccardo Dolcetti, Ranjeny Thomas   +11 more
wiley   +1 more source

Molecular epidemiology of human Adenovirus among patients with Keratoconjunctivitis

Zanco Journal of Pure and Applied Sciences, 2019
Various Human Adenoviruses (HAdV) serotypes are reported to be accompanied with keratoconjunctivitis infections. Seventy-three conjunctival swabs were obtained from (39 male and 34 female) who presented to the ophthalmic unite in the hospital of Erbil ...
Sazan Qadir Maulud
doaj   +1 more source

Integrating oncolytic adenoviruses into combination cancer therapy: Mechanisms, advances and clinical outlook

Clinical and Translational Medicine, Volume 16, Issue 5, May 2026.
Oncolytic adenoviruses synergise with chemotherapy, radiotherapy and immunotherapy to enhance anti‐tumour efficacy. Chemotherapy and radiotherapy increase tumour susceptibility and antigen release through DNA damage, while immunotherapy restores T‐cell activity.
Vlad Iova, Gilda Mihaela Iova, Mihail Silviu Tudosie, Ioana Scrobota, Catalin Gabriel Smarandache   +4 more
wiley   +1 more source

Phylogenetic tree based on nucleotide sequence of hexon gene of FAdV field isolates and sequences from gene bank.

, 2019
Phylogenetic tree based on nucleotide sequence of hexon gene of FAdV field isolates and sequences from gene bank.
Khalil Zro (8208792), Mohammed Mouahid (4891021), Samira Abghour (8208789), Jaouad Berrada (8208801), Faouzi Kichou (4891027), Meriam Tarta (8208798), Fatima Tahiri (8208795)   +6 more
core   +1 more source

Oncolytic Therapy: Delivery System and New Therapeutic Strategies for Cancer

MedComm, Volume 7, Issue 4, April 2026.
This review summarizes recent advances in nanoparticle‐ and cell‐mediated OVs delivery strategies that improve biodistribution and tumor targeting while limiting immune clearance. It also examines combination approaches that enhance therapeutic efficacy through tumor microenvironment modulation or immune activation, thereby overcoming immunosuppression
Sikan Jin, Yi Zhang, Ziling Zhou, Yaqi Zhang, Ting Yu, Rui Xu, Lin Xu, Jidong Zhang, Longze Zhang, Shan Yang, Xianyao Wang   +10 more
wiley   +1 more source

An image cytometric technique is a concise method to detect adenoviruses and host cell proteins and to monitor the infection and cellular responses induced

Virology Journal, 2017
Background Genetically modified adenoviruses (Ad) with preferential replications in tumor cells have been examined for a possible clinical applicability as an anti-cancer agent. A simple method to detect viral and cellular proteins is valuable to monitor
Takao Morinaga, Thảo Thi Thanh Nguyễn, Boya Zhong, Michiko Hanazono, Masato Shingyoji, Ikuo Sekine, Yuji Tada, Koichiro Tatsumi, Hideaki Shimada, Kenzo Hiroshima, Masatoshi Tagawa   +10 more
doaj   +1 more source

Detection and identification of avian adenovirus in broiler chickens suspected of inclusion body hepatitis in Khuzestan, Iran during 2015-2016 [PDF]

The Iranian Journal of Veterinary Science and Technology, 2017
Avian adenoviruses (AAV) are known as a very diverse group of pathogens causing a variety of clinical symptoms or being totally asymptomatic in poultry flocks.
Parisasadat Tabib Ghafari, Zahra Boroomand, Anahita Rezaie, Mansoor Mayahi, Sara Eftekharian   +4 more
doaj   +1 more source

Comparative Sequence Analysis, Pathogenicity and Immunogenicity of Attenuated Fowl Adenovirus Isolates as Experimental Vaccines against Inclusion Body Hepatitis of Commercial Broiler Chickens

Vaccine Research, 2021
Introduction: Fowl adenoviruses (FAdV) cause inclusion body hepatitis (IBH) in chickens and new vaccination strategies against IBH are needed as an effective control measure in the poultry industry. Methods: The attenuated FAdV isolates from from chicken
NORFITRIAH MOHAMED SOHAIMI, Mohd Hair-Bejo   +1 more
doaj   +1 more source

Synergistic antiviral activity against human adenovirus through combination of itraconazole and brincidofovir

British Journal of Pharmacology, Volume 183, Issue 7, Page 1578-1601, April 2026.
Background and Purpose Human adenovirus (HAdV) causes respiratory or gastrointestinal tract infections depending on the virus subtype. While HAdV infections are generally self‐limiting in immunocompetent people, they can result in significant morbidity and mortality in immunocompromised adults and children.
Mohamed Zamzamy, Sophie Post, Wing Hang Ip, Elin Hahlin, Sebastian Kühn, Andrea Pirosu, Christian Conze, Martin Baumdick, Hamburg Intestinal Study Group, Madeleine J. Bunders, Britta F. Zecher, Angelique Hoelzemer, Stephan Linder, Niklas Arnberg, Thomas Dobner, Marcus Altfeld, Sebastian Schloer   +16 more
wiley   +1 more source

Comparative Sequence Analysis of the Hexon Gene in the Entire Spectrum of Human Adenovirus Serotypes: Phylogenetic, Taxonomic, and Clinical Implications [PDF]

Journal of Virology, 2005
ABSTRACT The adenovirus (AdV) hexon constitutes the major virus capsid protein. The epitopes located on the hexon protein are targets of neutralizing antibodies in vivo, serve in the recognition by cytotoxic T cells, and provide the basis for the classification of adenoviruses into the 51 serotypes known to date.
K, Ebner, W, Pinsker, T, Lion
openaire   +3 more sources