Results 1 to 10 of about 1,606 (180)

Binding of adenovirus species C hexon to prothrombin and the influence of hexon on vector properties in vitro and in vivo.

open access: yesPLoS Pathogens, 2022
The majority of adenovirus (Ad) vectors are based on human Ad type 5, which is a member of Ad species C. Species C also includes the closely-related types 1, 2, 6, 57 and 89.
Jie Tian   +5 more
doaj   +3 more sources

Requirement of Cellular Protein CCT7 for the Replication of Fowl Adenovirus Serotype 4 (FAdV-4) in Leghorn Male Hepatocellular Cells Via Interaction with the Viral Hexon Protein

open access: yesViruses, 2019
Fowl adenovirus serotype 4 (FAdV-4) causes hepatitis-hydropericardium syndrome (HHS), leading to severe economic losses in the poultry industry. Although the pathogenesis of FAdV-4 infection has caused much attention, the underlying molecular mechanisms ...
Junfeng Gao   +2 more
exaly   +3 more sources

A recent perspective on fiber and hexon genes proteins analyses of fowl adenovirus towards virus infectivity - A review [PDF]

open access: yesOpen Veterinary Journal, 2021
Fowl adenovirus (FAdV) is a double-stranded DNA virus with a non-enveloped structure comprising three major proteins known as hexon, penton, and fiber.
Norfitriah Mohamed Sohaimi   +1 more
doaj   +1 more source

The Role of Hexon Amino Acid 188 Varies in Fowl Adenovirus Serotype 4 Strains with Different Virulence

open access: yesMicrobiology Spectrum, 2022
Hepatitis-hydropericardium syndrome (HHS) induced by fowl adenovirus serotype 4 (FAdV-4) has caused huge economic losses to poultry industries. The key genes responsible for different virulence of FAdV-4 strains are not fully elucidated. Previous studies
Baiyu Wang   +7 more
doaj   +1 more source

Identification of a novel immunological epitope on Hexon of fowl adenovirus serotype 4

open access: yesAMB Express, 2021
Fowl adenovirus serotype 4 (FAdV-4), the causative agent of hepatitis-hydropericardium syndrome (HHS), distributed widely in the poultry farms in China. Hexon is one of the major capsid proteins associated with viral species or serotypes.
Jingyi Liu   +4 more
doaj   +1 more source

Immunological Study of Reconstructed Common Ancestral Sequence of Adenovirus Hexon Protein

open access: yesFrontiers in Microbiology, 2021
Aim: To reconstruct the ancestral sequence of human adenoviral hexon protein by combining sequence variations and structural information. And to provide a candidate hexon protein for developing new adenoviral vector capable of escaping the pre-existing ...
Yingchen Wang   +12 more
doaj   +1 more source

Identification of Recombinant Chimpanzee Adenovirus C68 Degradation Products Detected by AEX-HPLC

open access: yesFrontiers in Bioengineering and Biotechnology, 2022
Physicochemical tests represent important tools for the analytical control strategy of biotherapeutics. For adenoviral modalities, anion-exchange high performance liquid chromatography (AEX-HPLC) represents an important methodology, as it is able to ...
Thomas W. Powers   +6 more
doaj   +1 more source

Genetic diversity of fowl adenovirus serotype 8b isolated from cases of inclusion body hepatitis in commercial broiler chickens

open access: yesJournal of the Indonesian Tropical Animal Agriculture, 2022
Inclusion body hepatitis (IBH) is a devastating disease of chickens caused by Fowl adenovirus (FAdV) and molecular studies of hexon gene is important for classification of FAdV isolates, epidemiology of IBH infection and development of effective control ...
N. M. Sohaimi   +2 more
doaj   +1 more source

Molecular characterization and phylogenetic analysis of fowl adenovirus serotype-4 from Guangdong Province, China [PDF]

open access: yesVeterinary World, 2020
Aim: Our aim in this study was to isolate potentially novel strains of fowl adenovirus serotype-4 (FAdV-4) that is currently circulating in broiler chicken flocks in Guangdong Province, China, and to compare nucleotide and amino acid (AA) sequences of ...
Fu Yuming   +12 more
doaj   +1 more source

High Rates of Detection and Molecular Characterization of Porcine Adenovirus Serotype 5 (Porcine mastadenovirus C) from Diarrheic Pigs

open access: yesPathogens, 2022
Since the first report on isolation of porcine adenovirus serotype 5 (PAdV-5, species Porcine mastadenovirus C (PAdV-C)) from pigs with respiratory illness in Japan in 1987, PAdV-5 have been detected in a few fecal samples from healthy pigs and in some ...
Kerry Gainor   +5 more
doaj   +1 more source

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