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The majority of adenovirus (Ad) vectors are based on human Ad type 5, which is a member of Ad species C. Species C also includes the closely-related types 1, 2, 6, 57 and 89.
Jie Tian +5 more
doaj +3 more sources
Fowl adenovirus serotype 4 (FAdV-4) causes hepatitis-hydropericardium syndrome (HHS), leading to severe economic losses in the poultry industry. Although the pathogenesis of FAdV-4 infection has caused much attention, the underlying molecular mechanisms ...
Junfeng Gao +2 more
exaly +3 more sources
A recent perspective on fiber and hexon genes proteins analyses of fowl adenovirus towards virus infectivity - A review [PDF]
Fowl adenovirus (FAdV) is a double-stranded DNA virus with a non-enveloped structure comprising three major proteins known as hexon, penton, and fiber.
Norfitriah Mohamed Sohaimi +1 more
doaj +1 more source
Hepatitis-hydropericardium syndrome (HHS) induced by fowl adenovirus serotype 4 (FAdV-4) has caused huge economic losses to poultry industries. The key genes responsible for different virulence of FAdV-4 strains are not fully elucidated. Previous studies
Baiyu Wang +7 more
doaj +1 more source
Identification of a novel immunological epitope on Hexon of fowl adenovirus serotype 4
Fowl adenovirus serotype 4 (FAdV-4), the causative agent of hepatitis-hydropericardium syndrome (HHS), distributed widely in the poultry farms in China. Hexon is one of the major capsid proteins associated with viral species or serotypes.
Jingyi Liu +4 more
doaj +1 more source
Immunological Study of Reconstructed Common Ancestral Sequence of Adenovirus Hexon Protein
Aim: To reconstruct the ancestral sequence of human adenoviral hexon protein by combining sequence variations and structural information. And to provide a candidate hexon protein for developing new adenoviral vector capable of escaping the pre-existing ...
Yingchen Wang +12 more
doaj +1 more source
Identification of Recombinant Chimpanzee Adenovirus C68 Degradation Products Detected by AEX-HPLC
Physicochemical tests represent important tools for the analytical control strategy of biotherapeutics. For adenoviral modalities, anion-exchange high performance liquid chromatography (AEX-HPLC) represents an important methodology, as it is able to ...
Thomas W. Powers +6 more
doaj +1 more source
Inclusion body hepatitis (IBH) is a devastating disease of chickens caused by Fowl adenovirus (FAdV) and molecular studies of hexon gene is important for classification of FAdV isolates, epidemiology of IBH infection and development of effective control ...
N. M. Sohaimi +2 more
doaj +1 more source
Molecular characterization and phylogenetic analysis of fowl adenovirus serotype-4 from Guangdong Province, China [PDF]
Aim: Our aim in this study was to isolate potentially novel strains of fowl adenovirus serotype-4 (FAdV-4) that is currently circulating in broiler chicken flocks in Guangdong Province, China, and to compare nucleotide and amino acid (AA) sequences of ...
Fu Yuming +12 more
doaj +1 more source
Since the first report on isolation of porcine adenovirus serotype 5 (PAdV-5, species Porcine mastadenovirus C (PAdV-C)) from pigs with respiratory illness in Japan in 1987, PAdV-5 have been detected in a few fecal samples from healthy pigs and in some ...
Kerry Gainor +5 more
doaj +1 more source

