Results 11 to 20 of about 1,606 (180)
Unveiling the role of hexon-associated host proteins in fowl adenovirus serotype 4 replication [PDF]
Frontiers in Veterinary ScienceFowl adenovirus serotype 4 (FAdV-4), a member of the family Adenoviridae and the genus Aviadenovirus, is responsible for a significant number of emerging diseases that cause substantial economic losses in the poultry industry worldwide. The hexon protein
Xiaojun Zhang +4 more
doaj +2 more sources
Microbiology Indonesia, 2023 Adenovirus type 5 (Ad5) is one of the vaccine vectors, including the COVID-19 vaccine. Pre-existing immunity to Ad5 may suppress the immunogenicity and efficacy of adenovirus vectored vaccine. The neutralizing antibodies are directed specifically toward
Afina Firdaus Syuaib +2 more
doaj +2 more sources
Structure-based high-throughput epitope analysis of hexon proteins in B and C species human adenoviruses (HAdVs). [PDF]
PLoS ONE, 2012 Human adenoviruses (HAdVs) are the etiologic agent of many human infectious diseases. The existence of at least 54 different serotypes of HAdVs has resulted in difficulties in clinical diagnosis.
Xiao-Hui Yuan +11 more
doaj +2 more sources
Modification of Ad5 hexon hypervariable regions circumvents pre-existing Ad5 neutralizing antibodies and induces protective immune responses. [PDF]
PLoS ONE, 2012 The development of an effective malaria vaccine is a high global health priority. Vaccine vectors based on adenovirus type 5 are capable of generating robust and protective T cell and antibody responses in animal models and are currently being evaluated ...
Joseph T Bruder +11 more
doaj +3 more sources
Protection against enterovirus 71 with neutralizing epitope incorporation within adenovirus type 3 hexon. [PDF]
PLoS ONE, 2012 Enterovirus 71 (EV71) is responsible for hand, foot and mouth disease with high mortality among children. Various neutralizing B cell epitopes of EV71 have been identified as potential vaccine candidates. Capsid-incorporation of antigens into adenovirus (
Xingui Tian +7 more
doaj +2 more sources
Poultry ScienceSince 2015, hepatitis-hydropericardium syndrome (HHS) induced by the infection of highly pathogenic serotype 4 fowl adenovirus (HP-FAdV-4) has caused severe economic losses to the poultry industry.
Ye Tang +13 more
doaj +2 more sources
Hydropathic characteristics of adenovirus hexons [PDF]
Archives of Virology, 1997 The complete nucleotide sequence and the predicted amino acid sequence of the adenovirus type 7 hexon gene were determined. The hydropathy of the hexon proteins from human adenovirus types 2, 3, 4, 5, 7, 12, 16, 40, 41, and 48, bovine adenovirus type 3, murine adenovirus type 1, and avian adenovirus types 1 and 10 was analysed.
Li, Q.-G., Lindman, K., Wadell, G.
openaire +2 more sources
Recombinant hexon protein as a new bovine adenovirus type 3 subunit vaccine candidate
Journal of Veterinary Research, 2023 Bovine adenovirus (BAdV) type 3 causes respiratory and gastroenteric diseases of varying severity in cattle, particularly newborn calves. Trials have been conducted of a vaccination against the diseases caused by BAdV using both modified live-virus and ...
Gundegmaa Uudamsaikhan +5 more
doaj +1 more source
Optical Properties of the Hexon of Adenovirus [PDF]
European Journal of Biochemistry, 1972 The ultraviolet absorbance, circular dichroism (CD) and optical rotatory dispersion of the hexons of adenovirus type 2 have been measured and analyzed in terms of secondary structural features. A curve‐fitting method for the CD spectra from 190 nm to 240 nm indicates 170%‐α‐helical, 26%β, and 56%, “random” conformations; the classical parameter b0 ...
L A, Day +3 more
openaire +2 more sources
Hexon peptides of type 2, 3, and 5 adenoviruses and their relationship to hexon structure [PDF]
Journal of Virology, 1975 Peptides of hexons from type 2 and 5 (subgroup III) and type 3 (subgroup I) adenoviruses were produced by treatment with cyanogen bromide and were separated by isoelectric focusing in polyacrylamide gels containing 8 M urea. Peptides with identical isoelectric points, but from different hexon types, were considered to have structural similarities ...
M F, Stinski, H S, Ginsberg
openaire +2 more sources