Results 71 to 80 of about 7,225 (221)

Genome-wide transcriptional profiling of appressorium development by the rice blast fungus Magnaporthe oryzae. [PDF]

, 2012
addresses: College of Life and Environmental Sciences, University of Exeter, Exeter, United Kingdom.notes: PMCID: PMC3276559The rice blast fungus Magnaporthe oryzae is one of the most significant pathogens affecting global food security.
A Conesa, A Djamei, A Gupta, AH Osmani, Angus L. Dawe, Apratim Chakrabarti, B Langmead, Barbara J. Howlett, C Trapnell, C Trapnell, C Veneault-Fourrey, CB Sun, CL Holt, CS Harwood, D Parker, DA Guertin, Darren M. Soanes, DG Saunders, DG Saunders, DM Soanes, E Szewczyk, E Thines, FG Chumley, GK Bhambra, H Leung, H Matsumura, HK Lamb, HU Bohnert, JC de Jong, JC Marioni, JM Crawford, JR Xu, K Adachi, Konrad H. Paszkiewicz, LX Xiang, M Brock, M Gowda, M Hasslacher, M Ramos-Pamplona, M Urban, MA Lubkowitz, MJ Kershaw, MJ Kershaw, Nicholas J. Talbot, NJ Talbot, NJ Talbot, NM Donofrio, P Mazur, PGS Skamnioti, RA Dean, RA Musrati, RA Wilson, RA Wilson, RF Geever, S Anders, S Kim, S Ohtaki, SL Tucker, SM Mathioni, X Zhao, Y Oh, YW Asmann, Z Wang, ZX Liu W, ZY Wang, ZY Wang   +65 more
core   +5 more sources

Identification of β‐galactosidases along the secretory pathway of Nicotiana benthamiana that collectively hamper engineering of galactose‐extended glycans on recombinant glycoproteins

Plant Biotechnology Journal, Volume 24, Issue 1, Page 224-238, January 2026.
Summary Glycosylation is an important aspect for many biopharmaceuticals, including vaccines against parasitic helminths. Plants, especially Nicotiana benthamiana, have proven to be excellent production hosts for biopharmaceuticals with tailor‐made glycosylation.
Alex van der Kaaij, Myrna J. M. Bunte, Lisa Nijhof, Sanaz Mokhtari, Hein Overmars, Arjen Schots, Ruud H. P. Wilbers, Pieter Nibbering   +7 more
wiley   +1 more source

GM2-Gangliosidosis (Sandhoff and Tay Sachs disease): Diagnosis and Neuroimaging Findings (An Iranian Pediatric Case Series) [PDF]

, 2014
How to Cite This Article: Karimzadeh P, Jafari N, Nejad Biglari H, Jabbeh Dari S, Ahmad Abadi F, Alaee MR, Nemati H, Saket S,Tonekaboni SH, Taghdiri MM, Ghofrani M. GM2-Gangliosidosis (Sandhoff and Tay Sachs disease): Diagnosis and Neuroimaging Findings (
AHMAD ABADI, Farzad, ALAEE, Mohammad-Reza, GHOFRANI, Mohammad, JABBEH DARI, Sayena, JAFARI, Narjes, KARIMZADEH, Parvaneh, NEJAD BIGLARI, Habibeh, NEMATI, Hamid, SAKET, Sasan, TAGHDIRI, Mohammad-Mahdi, TONEKABONI, Seyed Hassan   +10 more
core   +2 more sources

N-acetyl-β-D-hexosaminidases mediate the generation of paucimannosidic proteins via a putative noncanonical truncation pathway in human neutrophils.

Glycobiology, 2021
Julian Ugonotti, R. Kawahara, Ian Loke, Yuqi Zhu, S. Chatterjee, Harry C. Tjondro, Zeynep Sumer-Bayraktar, S. Neelamegham, M. Thaysen‐Andersen   +8 more
semanticscholar   +1 more source

Proteomic analysis links truncated tau to lysosome motility, autophagy, and endo‐lysosomal dysfunction

Alzheimer's &Dementia, Volume 21, Issue 12, December 2025.
Abstract INTRODUCTION Tauopathies involve progressive accumulation of abnormal tau species that disrupt the autophagy‐lysosomal pathway (ALP), critical for degrading intracellular macromolecules and aggregates, leading to toxicity and cell death. This study examines how overexpression of the N‐terminally truncated Tau35 protein affects proteolytic ...
Despoina Goniotaki, Maximilian Hausherr, Steven Lynham, Ayushin Ale, George Chennell, Stefania Marcotti, Katrin Marcus, Wendy Noble, Diane P. Hanger, Graham Fraser, Deepak P. Srivastava   +10 more
wiley   +1 more source

A Case Report of Sandhoff Disease [PDF]

, 2010
Sandhoff disease is a rare and severe lysosomal storage disorder representing 7% of GM2 gangliosidoses. Bilateral thalamic involvement has been suggested as a diagnostic marker of Sandhoff disease.
A Yüksel, A. Hanine, B Wilken, CJ Hendriksz, H. Boumdin, JP Lowe, K Hittmair, LG Gutierrez-Solana, M. Mahi, MC Nassogne, O. Agader, R. Abilkacem, R. Saouab, S. Chaouir, T Autti, T. Amil, W Kölfen   +16 more
core   +2 more sources

Serous Cavity Mast Cells Depend on the ROQUIN Paralogs

European Journal of Immunology, Volume 55, Issue 12, December 2025.
The RNA‐binding ROQUIN paralogs are critical immune regulators. We demonstrate that mast cell‐specific deficiency for ROQUIN‐1 and ROQUIN‐2 in mice leads to loss of mast cells in serous cavities. ROQUIN‐1 and 2 ablation does not affect mast cell degranulation or proinflammatory cytokine secretion, although they regulate many mRNAs directly or ...
Klaus Heger, Ali Masjedi, Assa Yeroslaviz, Theodor Zeng, Seren Baygün, Angela Vicente‐Luque, Chia‐I. Lien, Lena Osswald, Dieter Saur, Daniel Kovacs, Marc Schmidt‐Supprian   +10 more
wiley   +1 more source

Comparative Genomics and Virulence Mechanisms to Identify Genes Related to Mucin O‐Glycan Degradation and Pathogenicity in a Potentially Multidrug‐Resistant Clostridium tertium Strain

MicrobiologyOpen, Volume 14, Issue 6, December 2025.
The comparative genomic analysis provides information about how C. tertium HGMC01 strain cause disease through mucin glycan degradation, colonization, multidrug resistance, and modulation of immune responses. Moreover, this analysis data suggest that this strain interacts with host cells by degrading mucin in the gut, potentially through recognition or
Seonghun Kim, Ji Young Kang, Jung‐Sook Lee   +2 more
wiley   +1 more source

Familial X-linked cardiomyopathy (Danon disease): diagnostic confirmation by mutation analysis of the LAMP2 gene [PDF]

, 2018
A boy presented at age 2.5 years with mild left ventricular hypertrophy and mild myopathy. Hypertrophic cardiomyopathy progressed relentlessly, leading to death at age 16 years shortly before planned heart transplantation.
Ballhausen, Diana, Balmer, Christian, Bauersfeld, Urs, Boltshauser, Eugen, Bosshard, Nils, Steinmann, Beat, Superti-Furga, Andrea   +6 more
core  

Ruthenibacterium lactatiformans gen. nov., sp.nov., an anaerobic, lactate-producing member of the family Ruminococcaceae isolated from human faeces [PDF]

, 2016
Two novel strains of Gram-stain-negative, rod-shaped, obligately anaerobic, non-spore-forming, non-motile bacteria were isolated from the faeces of healthy human subjects.
Bozhenko, Vladimir K., Chaplin, Andrei V., Efimov, Boris A., Kafarskaia, Lyudmila I., Shcherbakova, Victoria A., Shkoporov, Andrei N., Suzina, Natalia E.   +6 more
core   +1 more source