Bacterial small noncoding RNAs (sRNAs) play posttranscriptional regulatory roles in cellular responses to changing environmental cues and in adaptation to harsh conditions. Generally, the RNA-binding protein Hfq helps sRNAs associate with target mRNAs to
Kotaro Chihara +6 more
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An upstream Hfq binding site in the fhlA mRNA leader region facilitates the OxyS-fhlA interaction.
BackgroundTo survive, bacteria must be able to adapt to environmental stresses. Small regulatory RNAs have been implicated as intermediates in a variety of stress-response pathways allowing dynamic gene regulation. The RNA binding protein Hfq facilitates
Nilshad N Salim, Andrew L Feig
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New aspects of RNA-Based Regulation by Hfq and its partner sRNAs
Hfq, an RNA chaperone, promotes the pairing of small RNAs (sRNAs) to target mRNAs, mediating post-transcriptional regulation of mRNA stability and translation. This regulation contributes to bacterial adaptation during stress and pathogenesis.
K. Kavita +2 more
semanticscholar +1 more source
To adapt to stresses encountered in stationary phase, Gram-negative bacteria utilize the alternative sigma factor RpoS. However, some species lack RpoS; thus, it is unclear how stationary-phase adaptation is regulated in these organisms.
Dharanesh Gangaiah +13 more
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Dual Role of Small Noncoding RNA and Hfq in Bacterial DNA Compaction: A New Perspective on Nucleoid Architecture. [PDF]
Mistygacz G +6 more
europepmc +1 more source
Polyphosphate modulates the stress-responsive formation of functional RNA-protein condensates in bacteria and mammalian cells. [PDF]
Guan J +9 more
europepmc +1 more source
Hfq-dependent artificial regulatory small RNAs for targeted gene expression control in the nitrogen-fixing <i>Pseudomonas stutzeri</i> A1501. [PDF]
Han Y +7 more
europepmc +1 more source
<sup>19</sup>F NMR Strategy for Probing Site-specific RNA Dynamics in Large RNA-protein Complexes: Application to the Hfq RNA Chaperone. [PDF]
White EN +5 more
europepmc +1 more source
Glutathione impacts Hfq condensation in nitrogen-starved <i>Escherichia coli</i>. [PDF]
Ellis HR +4 more
europepmc +1 more source
Study on the impact of Hfq regulation on spoilage odor formation by <i>Pantoea agglomerans</i> inoculated onto chilled chicken meat. [PDF]
Wang X +11 more
europepmc +1 more source

