Results 111 to 120 of about 6,621 (215)

Hfq Is Necessary for Regulation by the Untranslated RNA DsrA [PDF]

Journal of Bacteriology, 2001
ABSTRACTDsrA is an 85-nucleotide, untranslated RNA that has multiple regulatory activities at 30°C. These activities include the translational regulation of RpoS and H-NS, global transcriptional regulators inEscherichia coli. Hfq is anE. coliprotein necessary for the in vitro and in vivo replication of the RNA phage Qβ.
D D, Sledjeski, C, Whitman, A, Zhang
openaire   +2 more sources

Quantitative proteomic analysis of the Hfq-regulon in Sinorhizobium meliloti 2011. [PDF]

PLoS ONE, 2012
Riboregulation stands for RNA-based control of gene expression. In bacteria, small non-coding RNAs (sRNAs) are a major class of riboregulatory elements, most of which act at the post-transcriptional level by base-pairing target mRNA genes.
Patricio Sobrero, Jan-Philip Schlüter, Ulrike Lanner, Andreas Schlosser, Anke Becker, Claudio Valverde   +5 more
doaj   +1 more source

The FsrA‐Mediated Iron‐Sparing Response Regulates the Biosynthesis of the Epipeptide EPE in Bacillus subtilis

Molecular Microbiology, Volume 125, Issue 2, Page 108-122, February 2026.
Under iron‐limited conditions, FsrA base‐pairs with the intergenic region between epeX and epeE, enhancing epeE translation and triggering EPE production. Toxin‐mediated cell lysis releases nutrients, including iron, which can be taken up by surviving cells.
Sarah Miercke, Rabea Ghandour, Kai Papenfort, Thorsten Mascher   +3 more
wiley   +1 more source

Hfq proximity and orientation controls RNA annealing [PDF]

Nucleic Acids Research, 2012
Regulation of bacterial gene networks by small non-coding RNAs (sRNAs) requires base pairing with messenger RNA (mRNA) targets, which is facilitated by Hfq protein. Hfq is recruited to sRNAs and mRNAs through U-rich- and A-rich-binding sites, respectively, but their distance from the sRNA-mRNA complementary region varies widely among different genes ...
Panja, Subrata, Woodson, Sarah A.
openaire   +2 more sources

Epigallocatechin Gallate Remodelling of Hfq Amyloid-Like Region Affects Escherichia coli Survival

Pathogens, 2018
Hfq is a pleiotropic regulator that has key roles in the control of genetic expression. The protein noticeably regulates translation efficiency and RNA decay in Gram-negative bacteria, due to the Hfq-mediated interaction between small regulatory ...
David Partouche, Florian Turbant, Omar El Hamoui, Camille Campidelli, Marianne Bombled, Sylvain Trépout, Frank Wien, Véronique Arluison   +7 more
doaj   +1 more source

Virulence Regulation and Lifestyle Transitions: The Role of c‐di‐GMP and Two‐Component Systems in Erwinia amylovora and Their Evolutionary Context Within Enterobacterales

Molecular Plant Pathology, Volume 27, Issue 2, February 2026.
Erwinia amylovora infects apple blossoms by activating the T3SS, then spreads systemically via amylovoran‐mediated biofilms. Transitions between motile and sessile states are regulated by key two‐component systems and c‐di‐GMP. This review summarises infection biology, virulence factors, regulatory networks and evolutionary insights underlying fire ...
Dhirendra Niroula, Kalyani Bhandari, George W. Sundin, Janak R. Joshi   +3 more
wiley   +1 more source

Hfq variant with altered RNA binding functions [PDF]

Nucleic Acids Research, 2006
The interaction between Hfq and RNA is central to multiple regulatory processes. Using site-directed mutagenesis, we have found a missense mutation in Hfq (V43R) which strongly affects2 the RNA binding capacity of the Hfq protein and its ability to stimulate poly(A) tail elongation by poly(A)-polymerase in vitro.
Ziolkowska, K., Ph, Derreumaux, Folichon, M., Pellegrini, O., Ph, Regnier, Boni, I., Hajnsdorf, E.   +6 more
openaire   +3 more sources

Dual‐Pathway Defense: Ultramicro‐Pulverised Powder of Polygonum chinense L. and Atractylodes rhizome (PAUP) Rescues Broilers From E. coli‐Triggered Liver Injury Through Modulation of Oxidative Stress and Inflammation

Food Science &Nutrition, Volume 14, Issue 1, January 2026.
Reduced Antibiotic residues and resistance concerns: Offers a potential natural alternative to antibiotics for combating E. coli infections in poultry. Provided safer poultry food products: By enhancing liver function, restoring weight gain, and improving feed efficiency, PAUP supports the production of healthier chickens, ultimately contributing to ...
Jia‐Ci Cai, Yan‐Na Guo, Shao‐Shan Liang, Yan Liu, Fu‐Qiang Huang, Qi‐Peng Lv, Lan‐Yi Zhang, Yi Qin, Xiao‐Jing Chen, Yu‐Xin Liang, Yong‐Ming He, Lu‐Ping Tang   +11 more
wiley   +1 more source

Fluorescence Reporters for Hfq Oligomerization and RNA Annealing [PDF]

, 2014
Fluorescence spectroscopy is a sensitive technique for detecting protein-protein, protein-RNA, and RNA-RNA interactions, requiring only nanomolar concentrations of labeled components. Fluorescence anisotropy provides information about the assembly of multi-subunit proteins, while molecular beacons provide a sensitive and quantitative reporter for base ...
Subrata, Panja, Sarah A, Woodson
openaire   +2 more sources

Deletion of the small RNA chaperone protein Hfq down regulates genes related to virulence and confers protection against wild-type Brucella challenge in mice

Frontiers in Microbiology, 2016
Brucellosis is one of the most common zoonotic epidemics worldwide. Brucella, the etiological pathogen of brucellosis, has unique virulence characteristics, including the ability to survive within the host cell.
Shuangshuang eLei, Zhijun eZhong, Yuehua eKe, Mingjuan eYang, Xiaoyang eXu, Hang eRen, Chang eAn, Jiuyun eYuan, Jiuxuan eYu, Jie eXu, Yanchun eShi, Yefeng eQiu, Yufei eWang, Guangneng ePeng, Zeliang eChen, Zeliang eChen   +15 more
doaj   +1 more source