Results 101 to 110 of about 6,261 (210)

Interplay between the catabolite repression control protein Crc, Hfq and RNA in Hfq-dependent translational regulation in Pseudomonas aeruginosa

, 2017
In Pseudomonas aeruginosa the RNA chaperone Hfq and the catabolite repression control protein (Crc) act as post-transcriptional regulators during carbon catabolite repression (CCR).
Pei, Xue-Yuan (Department of Biochemistry, University of Cambridge), Abdou, Laetitia (Department of Fundamental Microbiology, University of Lausanne), Urlaub, Henning (Biophysical Mass Spectrometry Group, Max Planck Institute for Biophysical Chemistry), Campagne, Sébastien (Institute of Molecular Biology and Biophysics, ETH Zürich), Luisi, Ben F (Department of Biochemistry, University of Cambridge), Prindl, Konstantin (Department of Microbiology, Immunobiology and Genetics, Centre for Molecular Biology, University of Vienna), Sonnleitner, Elisabeth (Department of Microbiology, Immunobiology and Genetics, Centre for Molecular Biology, University of Vienna), Forlani, Giada (Department of Microbiology, Immunobiology and Genetics, Centre for Molecular Biology, University of Vienna), Resch, Armin (Department of Microbiology, Immunobiology and Genetics, Centre for Molecular Biology, University of Vienna), Wulf, Alexander (Biophysical Mass Spectrometry Group, Max Planck Institute for Biophysical Chemistry), Wolfinger, Michael T (Department of Theoretical Chemistry, Faculty of Chemistry, University of Vienna), Bläsi, Udo (Department of Microbiology, Immunobiology and Genetics, Centre for Molecular Biology, University of Vienna), Allain, Frederic H -T (Institute of Molecular Biology and Biophysics, ETH Zürich)   +12 more
core   +1 more source

Archaeal protein containing domain of unknown function 2193 undergoes oligomeric reconfiguration upon iron–sulfur cluster binding

FEBS Letters, Volume 599, Issue 16, Page 2318-2333, August 2025.
This work presents the characterization of MvoDUF2193, a Methanococcus voltae (Mvo) protein from the domain of unknown function (DUF) 2193 family. We demonstrate that MvoDUF2193 binds a single [4Fe–4S] cluster per subunit and that cluster occupancy regulates the transition from an apo tetramer to a [4Fe–4S] monomeric form. This structural transition is
Emily M. Dieter, James Larson, Monika Tokmina‐Lukaszewska, Jin Xiong, Jared Green, Yisong Guo, William E. Broderick, Brian Bothner, Joan B. Broderick   +8 more
wiley   +1 more source

Staphylococcus aureus staphyloxanthin expression is not controlled by Hfq

, 2019
Objective The golden color of Staphylococcus aureus is due to the synthesis of carotenoid pigments. In Gram-negative bacteria, Hfq is a global posttranscriptional regulator, but its function in S. aureus remains obscure. The absence of Hfq in S.
Bohn, Chantal, Liu, Wenfeng, Boudry, Pierre, Bouloc, Philippe   +3 more
core   +1 more source

Table_4_Functional Characterization of a Global Virulence Regulator Hfq and Identification of Hfq-Dependent sRNAs in the Plant Pathogen Pantoea ananatis.XLSX

, 2019
To successfully infect plant hosts, the collective regulation of virulence factors in a bacterial pathogen is crucial. Hfq is an RNA chaperone protein that facilitates the small RNA (sRNA) regulation of global gene expression at the post-transcriptional ...
Teresa A. Coutinho (7369301), Divine Y. Shyntum (7369298), Gi Yoon Shin (7369295), Jeffrey K. Schachterle (5755484), George W. Sundin (7252556), Lucy N. Moleleki (3636247)   +5 more
core   +1 more source

Impact of Hfq on the intrinsic drug resistance of Salmonella enterica serovar Typhimurium

Frontiers in Microbiology, 2012
Salmonella enterica is an important enteric pathogen, and its various serovars cause both systemic and intestinal diseases in humans and domestic animals.
Mitsuko eHayashi-Nishino, Aiko eFukushima, Kunihiko eNishino   +2 more
doaj   +1 more source

Image_7_Functional Characterization of a Global Virulence Regulator Hfq and Identification of Hfq-Dependent sRNAs in the Plant Pathogen Pantoea ananatis.TIF

, 2019
To successfully infect plant hosts, the collective regulation of virulence factors in a bacterial pathogen is crucial. Hfq is an RNA chaperone protein that facilitates the small RNA (sRNA) regulation of global gene expression at the post-transcriptional ...
Teresa A. Coutinho (7369301), Divine Y. Shyntum (7369298), Gi Yoon Shin (7369295), Jeffrey K. Schachterle (5755484), George W. Sundin (7252556), Lucy N. Moleleki (3636247)   +5 more
core   +1 more source

An improved method for surface immobilisation of RNA: application to small Non-Coding RNA - mRNA pairing [PDF]

, 2013
Characterisation of RNA and its intermolecular interactions is increasing in importance as the inventory of known RNA functions continues to expand. RNA-RNA interactions are central to post-transcriptional gene regulation mechanisms in bacteria, and the ...
Darren M. Gowers (485354), Jack O Phillips, Anastasia J Callaghan, Vincent, H., Andrew R. Pickford (485355), Adam J Roberts, Louise E. Butt (485353), Stone, Carlanne, Charlotte E. Mardle (485352), Henderson, Charlotte, Adam J. Roberts (485350), Pickford, Andy, Carlanne M Stone, Roberts, Adam J., Butt, Louise, Charlotte A Henderson, Louise E Butt, Anastasia J. Callaghan (485356), Helen A Vincent, Charlotte E Mardle, Callaghan, Anastasia, Carlanne M. Stone (485351), Phillips, Jack, Jack O. Phillips (485348), Charlotte A. Henderson (485349), Gowers, Darren, Mardle, C., Andrew R Pickford, Helen A. Vincent (485347), Darren M Gowers   +29 more
core   +1 more source

Hfq [PDF]

Molecular Cell, 2002
Møller, Thorleif, Franch, Thomas, Højrup, Peter, Keene, Douglas R, Bächinger, Hans Peter, Brennan, Richard G, Valentin-Hansen, Poul   +6 more
openaire   +1 more source

The RNA chaperone Hfq has a multifaceted role in Edwardsiella ictaluri

Frontiers in Cellular and Infection Microbiology
Edwardsiella ictaluri is a Gram-negative, facultative intracellular bacterium that causes enteric septicemia in catfish (ESC). The RNA chaperone Hfq (host factor for phage Qβ replication) facilitates gene regulation via small RNAs (sRNAs) in various ...
Ali Akgul, Safak Kalindamar, Adef O. Kordon, Hossam Abdelhamed, Iman Ibrahim, Hasan C. Tekedar, Attila Karsi   +6 more
doaj   +1 more source

Conditional Hfq Association with Small Noncoding RNAs in Pseudomonas aeruginosa Revealed through Comparative UV Cross-Linking Immunoprecipitation Followed by High-Throughput Sequencing

mSystems, 2019
Bacterial small noncoding RNAs (sRNAs) play posttranscriptional regulatory roles in cellular responses to changing environmental cues and in adaptation to harsh conditions. Generally, the RNA-binding protein Hfq helps sRNAs associate with target mRNAs to
Kotaro Chihara, Thorsten Bischler, Lars Barquist, Vivian A. Monzon, Naohiro Noda, Jörg Vogel, Satoshi Tsuneda   +6 more
doaj   +1 more source