Results 101 to 110 of about 10,886 (208)

Distinctive Regulation of Carbapenem Susceptibility in Pseudomonas aeruginosa by Hfq

Frontiers in Microbiology, 2020
Carbapenems are often the antibiotics of choice to combat life threatening infections caused by the opportunistic human pathogen Pseudomonas aeruginosa. The outer membrane porins OprD and OpdP serve as entry ports for carbapenems.
Elisabeth Sonnleitner, Petra Pusic, Michael T. Wolfinger, Michael T. Wolfinger, Udo Bläsi   +4 more
doaj   +1 more source

Conserved mycobacterial sRNA B11 regulates lipooligosaccharide synthesis at posttranscriptional level in Mycobacterium marinum

mLife, Volume 4, Issue 4, Page 447-460, August 2025.
Abstract Extractable glycolipids of mycobacteria, such as lipooligosaccharides (LOSs), play crucial roles in responding to environmental stress and modulating the host immune response. Although the biosynthesis of LOS is likely regulated at multiple levels to ensure proper composition of the cell wall, the key regulators remain unknown.
Chuan Wang, Cheng Bei, Yufeng Fan, Qingyun Liu, Yue Ding, Howard E. Takiff, Qian Gao   +6 more
wiley   +1 more source

Epigallocatechin Gallate Remodelling of Hfq Amyloid-Like Region Affects Escherichia coli Survival

Pathogens, 2018
Hfq is a pleiotropic regulator that has key roles in the control of genetic expression. The protein noticeably regulates translation efficiency and RNA decay in Gram-negative bacteria, due to the Hfq-mediated interaction between small regulatory ...
David Partouche, Florian Turbant, Omar El Hamoui, Camille Campidelli, Marianne Bombled, Sylvain Trépout, Frank Wien, Véronique Arluison   +7 more
doaj   +1 more source

Microfluidic Devices for Manufacture of Therapeutic Extracellular Vesicles: Advances and Opportunities

Journal of Extracellular Vesicles, Volume 14, Issue 7, July 2025.
ABSTRACT Extracellular vesicles (EVs) are emerging as promising candidates in therapeutic applications due to their unique ability to mediate intercellular communication and deliver biological cargo. With increasing interest in EV‐based therapies, the development of scalable, cost‐effective and regulatory‐compliant production methods is critical ...
Amin Hassanzadeh‐Barforoushi, Xenia Sango, Ella L. Johnston, David Haylock, Yuling Wang   +4 more
wiley   +1 more source

Extracellular Vesicles From Xylella fastidiosa Carry sRNAs and Genomic Islands, Suggesting Roles in Recipient Cells

Journal of Extracellular Vesicles, Volume 14, Issue 6, June 2025.
ABSTRACT Xylella fastidiosa (Xf) is a Gram‐negative bacterial plant pathogen responsible for severe diseases in a variety of economically important crops. A critical aspect of its virulence is the production of extracellular vesicles (EVs). In this study, we discovered that DNA‐binding proteins and nonribosomal RNA‐binding proteins are abundant in the ...
Alessa Ruf, Patrick Blumenkamp, Christina Ludwig, Anne Lippegaus, Andreas Brachmann, Andreas Klingl, Alexander Goesmann, Karina Brinkrolf, Kai Papenfort, Silke Robatzek   +9 more
wiley   +1 more source

Fluorescence Reporters for Hfq Oligomerization and RNA Annealing [PDF]

, 2014
Fluorescence spectroscopy is a sensitive technique for detecting protein-protein, protein-RNA, and RNA-RNA interactions, requiring only nanomolar concentrations of labeled components. Fluorescence anisotropy provides information about the assembly of multi-subunit proteins, while molecular beacons provide a sensitive and quantitative reporter for base ...
Subrata, Panja, Sarah A, Woodson
openaire   +2 more sources

Conditional Hfq Association with Small Noncoding RNAs in Pseudomonas aeruginosa Revealed through Comparative UV Cross-Linking Immunoprecipitation Followed by High-Throughput Sequencing

mSystems, 2019
Bacterial small noncoding RNAs (sRNAs) play posttranscriptional regulatory roles in cellular responses to changing environmental cues and in adaptation to harsh conditions. Generally, the RNA-binding protein Hfq helps sRNAs associate with target mRNAs to
Kotaro Chihara, Thorsten Bischler, Lars Barquist, Vivian A. Monzon, Naohiro Noda, Jörg Vogel, Satoshi Tsuneda   +6 more
doaj   +1 more source

Discovery of high-frequency quasi-periodic oscillations in the black-hole candidate IGR J17091-3624

, 2012
We report the discovery of 8.5 sigma high-frequency quasi-periodic oscillations (HFQPOs) at 66 Hz in the RXTE data of the black hole candidate IGR J17091-3624, a system whose X-ray properties are very similar to those of microquasar GRS 1915+105.
Altamirano, Diego, Belloni, Tomaso
core   +1 more source

The RNA chaperone Hfq has a multifaceted role in Edwardsiella ictaluri

Frontiers in Cellular and Infection Microbiology
Edwardsiella ictaluri is a Gram-negative, facultative intracellular bacterium that causes enteric septicemia in catfish (ESC). The RNA chaperone Hfq (host factor for phage Qβ replication) facilitates gene regulation via small RNAs (sRNAs) in various ...
Ali Akgul, Safak Kalindamar, Adef O. Kordon, Hossam Abdelhamed, Iman Ibrahim, Hasan C. Tekedar, Attila Karsi   +6 more
doaj   +1 more source

The Sinorhizobium meliloti RNA chaperone Hfq influences central carbon metabolism and the symbiotic interaction with alfalfa

BMC Microbiology, 2010
Background The bacterial Hfq protein is able to interact with diverse RNA molecules, including regulatory small non-coding RNAs (sRNAs), and thus it is recognized as a global post-transcriptional regulator of gene expression. Loss of Hfq has an extensive
Jiménez-Zurdo José I, Toro Nicolás, Rivilla Rafael, Lloret Javier, Jofré Edgardo, Peregrina Alexandra, Oruezabal Roke I, Torres-Quesada Omar   +7 more
doaj   +1 more source