Results 91 to 100 of about 6,261 (210)
Hfq variant with altered RNA binding functions [PDF]
Nucleic Acids Research, 2006 The interaction between Hfq and RNA is central to multiple regulatory processes. Using site-directed mutagenesis, we have found a missense mutation in Hfq (V43R) which strongly affects2 the RNA binding capacity of the Hfq protein and its ability to stimulate poly(A) tail elongation by poly(A)-polymerase in vitro.
Ziolkowska, K. +6 more
openaire +3 more sources
Epigallocatechin Gallate Remodelling of Hfq Amyloid-Like Region Affects Escherichia coli Survival
Pathogens, 2018 Hfq is a pleiotropic regulator that has key roles in the control of genetic expression. The protein noticeably regulates translation efficiency and RNA decay in Gram-negative bacteria, due to the Hfq-mediated interaction between small regulatory ...
David Partouche +7 more
doaj +1 more source
Mechanisms and Pathological Significance of Liquid–Liquid Phase Separation in Bacteria
The FASEB Journal, Volume 39, Issue 18, 30 September 2025.LLPS in bacterial infections. In biological systems, the molecular mechanisms underlying LLPS are primarily driven by multivalent protein–protein interactions, protein‐nucleic acid interactions, and intramolecular interactions mediated by IDR. Through LLPS, proteins form condensates that function as ‘microfactories,’ playing crucial roles in regulating
Yanxiao Zhao +5 more
wiley +1 more source
Fluorescence Reporters for Hfq Oligomerization and RNA Annealing [PDF]
, 2014 Fluorescence spectroscopy is a sensitive technique for detecting protein-protein, protein-RNA, and RNA-RNA interactions, requiring only nanomolar concentrations of labeled components. Fluorescence anisotropy provides information about the assembly of multi-subunit proteins, while molecular beacons provide a sensitive and quantitative reporter for base ...
Subrata, Panja, Sarah A, Woodson
openaire +2 more sources
Comprehensive Reviews in Food Science and Food Safety, Volume 24, Issue 5, September 2025.ABSTRACT Listeria monocytogenes is a foodborne pathogen that poses significant challenges to food safety and public health due to its ability to adapt to harsh environments, particularly those found in food processing facilities. This review explores the global transcriptional responses of L.
Nagendran Rajalingam, Sam Van Haute
wiley +1 more source
Frontiers in Microbiology, 2019 To successfully infect plant hosts, the collective regulation of virulence factors in a bacterial pathogen is crucial. Hfq is an RNA chaperone protein that facilitates the small RNA (sRNA) regulation of global gene expression at the post-transcriptional ...
Gi Yoon Shin +7 more
doaj +1 more source
Distinctive Regulation of Carbapenem Susceptibility in Pseudomonas aeruginosa by Hfq
Frontiers in Microbiology, 2020 Carbapenems are often the antibiotics of choice to combat life threatening infections caused by the opportunistic human pathogen Pseudomonas aeruginosa. The outer membrane porins OprD and OpdP serve as entry ports for carbapenems.
Elisabeth Sonnleitner +4 more
doaj +1 more source
Functional characterisation of Hfq and identification of Hfq-dependent sRNAs in Pantoea ananatis [PDF]
, 2020 Thesis (PhD)--University of Pretoria, 2020.The trans-encoded small RNAs (sRNAs) are novel gene expression regulators in bacteria. In response to external stimuli, sRNAs rapidly modulate the expression of genes at the post-transcriptional level to allow ...
core
Microbial Biotechnology, Volume 18, Issue 9, September 2025.Investigation of outer membrane vesicles from Acinetobacter baumannii for potential biotechnological applications. ABSTRACT Outer membrane vesicles (OMVs) are extracellular nanostructures released from Gram‐negative bacteria. Acinetobacter baumannii OMVs (AbOMVs) have been extensively studied and can thus be used as a model for understanding multiple ...
Beatriz Cano‐Castaño +5 more
wiley +1 more source
BMC Microbiology, 2010 Background The bacterial Hfq protein is able to interact with diverse RNA molecules, including regulatory small non-coding RNAs (sRNAs), and thus it is recognized as a global post-transcriptional regulator of gene expression. Loss of Hfq has an extensive
Jiménez-Zurdo José I +7 more
doaj +1 more source