Results 91 to 100 of about 10,886 (208)
Mechanisms and Pathological Significance of Liquid–Liquid Phase Separation in Bacteria
The FASEB Journal, Volume 39, Issue 18, 30 September 2025.LLPS in bacterial infections. In biological systems, the molecular mechanisms underlying LLPS are primarily driven by multivalent protein–protein interactions, protein‐nucleic acid interactions, and intramolecular interactions mediated by IDR. Through LLPS, proteins form condensates that function as ‘microfactories,’ playing crucial roles in regulating
Yanxiao Zhao +5 more
wiley +1 more source
Hfq and Hfq-dependent small RNAs are major contributors to multicellular development inSalmonella entericaserovar Typhimurium [PDF]
RNA Biology, 2012 The RNA chaperone Hfq and its associated small RNAs (sRNAs) regulate a variety of phenotypes in bacteria. In this work, we show that Hfq is a master regulator of biofilm formation in Salmonella enterica serovar Typhimurium. Hfq and two Hfq-dependent sRNAs (ArcZ and SdsR) are required for rdar morphotype expression in S. typhimurium.
Claudia, Monteiro +7 more
openaire +2 more sources
Interconnection of post-transcriptional regulation: The RNA-binding protein Hfq is a novel target of the Lon protease in Pseudomonas aeruginosa [PDF]
, 2015 Besides being a major opportunistic human pathogen, Pseudomonas aeruginosa can be found in a wide range of environments. This versatility is linked to complex regulation, which is achieved through the action of transcriptional regulators, and post ...
Bains, Manjeet +7 more
core +1 more source
Comprehensive Reviews in Food Science and Food Safety, Volume 24, Issue 5, September 2025.ABSTRACT Listeria monocytogenes is a foodborne pathogen that poses significant challenges to food safety and public health due to its ability to adapt to harsh environments, particularly those found in food processing facilities. This review explores the global transcriptional responses of L.
Nagendran Rajalingam, Sam Van Haute
wiley +1 more source
The RNA Chaperone Hfq Is Involved in Colony Morphology, Nutrient Utilization and Oxidative and Envelope Stress Response in Vibrio alginolyticus. [PDF]
PLoS ONE, 2016 Hfq is a global regulator that is involved in environmental adaptation of bacteria and in pathogenicity. To gain insight into the role of Hfq in Vibrio alginolyticus, an hfq deletion mutant was constructed in V.
Yiqin Deng +6 more
doaj +1 more source
Microbial Biotechnology, Volume 18, Issue 9, September 2025.Investigation of outer membrane vesicles from Acinetobacter baumannii for potential biotechnological applications. ABSTRACT Outer membrane vesicles (OMVs) are extracellular nanostructures released from Gram‐negative bacteria. Acinetobacter baumannii OMVs (AbOMVs) have been extensively studied and can thus be used as a model for understanding multiple ...
Beatriz Cano‐Castaño +5 more
wiley +1 more source
Frontiers in Microbiology, 2019 To successfully infect plant hosts, the collective regulation of virulence factors in a bacterial pathogen is crucial. Hfq is an RNA chaperone protein that facilitates the small RNA (sRNA) regulation of global gene expression at the post-transcriptional ...
Gi Yoon Shin +7 more
doaj +1 more source
FEBS Letters, Volume 599, Issue 16, Page 2318-2333, August 2025.This work presents the characterization of MvoDUF2193, a Methanococcus voltae (Mvo) protein from the domain of unknown function (DUF) 2193 family. We demonstrate that MvoDUF2193 binds a single [4Fe–4S] cluster per subunit and that cluster occupancy regulates the transition from an apo tetramer to a [4Fe–4S] monomeric form. This structural transition is
Emily M. Dieter +8 more
wiley +1 more source
Frontiers in Microbiology, 2016 Brucellosis is one of the most common zoonotic epidemics worldwide. Brucella, the etiological pathogen of brucellosis, has unique virulence characteristics, including the ability to survive within the host cell.
Shuangshuang eLei +15 more
doaj +1 more source
iMeta, Volume 4, Issue 4, August 2025.In this study, we found evidence of phage‐mediated horizontal transfer of virulence genes in Salmonella enterica in global habitats from a molecular evolutionary perspective. Notably, csrA, a global regulator in Salmonella enterica, curbed horizontal gene transfer by inhibiting the cyclization and release of prophage.
Tianjing She +9 more
wiley +1 more source